Information on SUBCLASS 11.8.1 |
Subclass Accession number: 3571
Subclass: 11.8.1 Type: EH beta-alpha DB: ArchDB95 Image coordinates: Consensus coordinates: Conserved Annotation EC : 1 (>75 %) 1.1 (>75 %) 1.1.1 (>75 %) 3 (>75 %) 4 (>75 %) GO : GO:0000107 (>75 %) GO:0016614 (>75 %) GO:0016615 (>75 %) GO:0016616 (>75 %) GO:0016757 (>75 %) GO:0016763 (>75 %) SCOP : 51366 (>75 %) 51367 (>75 %) 51734 (>75 %) 51735 (>75 %) 51848 (>75 %) |
Number of loops: 5 Average sequence ID (%) : 35.4 +/- 27.0 Average RMSD (Å) : 0.680 +/- 0.148 Consensus geometry
|
Consensus Sequence: | hhhhhXPpcPGXpRX |
(φψ)-conformation: | bbapbppppplppaa |
Pattern: | [MVWY] | [AV] | [ILV] | [ILV] | [AITV] | [AG] | [AG] | x | [PR] | [QR] | [GK] | [AP] | [G] | [EMQ] | [EST] | [R] | [akl] | [ADEQ] | [L] | [LV] | [DEGQ] | [aiv] | [NT] | [AGV] | [KNQR] | [IV] | [FLM] | [AKT] | [ade] | x | [AGM] | [KPR] | [AN] | [ILV] | [ADNSV] | [AEK] | [VY] |
Conservation: | -0.746 | -0.049 | 0.421 | 0.421 | -0.586 | 0.349 | 0.322 | -1.494 | 0.793 | 0.720 | -0.129 | 1.189 | 3.025 | -0.372 | -0.352 | 2.256 | -1.287 | -0.565 | 1.488 | 0.532 | -0.738 | -1.152 | 1.047 | -0.701 | -0.185 | 1.174 | 0.112 | -0.676 | -1.035 | -1.002 | -0.801 | -0.156 | -0.446 | 0.446 | -1.401 | -0.530 | 0.107 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a5z_*_93 | 1a5z | - | 93 | 129 | VVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKY | EEEE-------SS--HHHHHHHHHHHHHHHHHHHHHH | bbbbaxbbxpxxgpxaaaaaaaaaaaaaaaaaaaaaa |
1b8p_A_86 | 1b8p | A | 86 | 122 | VALLVGARPRGPGMERKDLLEANAQIFTVQGKAIDAV | EEEE-------TT--HHHHHHHHHHHHHHHHHHHHHH | bbbxaxbxxxxxvxxaaaaaaaaaaaaaaaaaaaaaa |
1iz9_A_83 | 1iz9 | A | 83 | 119 | YALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEV | EEEE-------TT--HHHHHHHHHHHHHHHHHHHHHH | bbbxaxbxxxbxvxxaaaaaaaaaaaaaaaaaaaaaa |
1lld_A_78 | 1lld | A | 78 | 114 | MVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKV | EEEE-------TT--HHHHHHHHHHHHHHHHHHHHHH | bbbxaxbxxxbxlxxaaaaaaaaaaaaaaaaaaaaaa |
7mdh_A_125 | 7mdh | A | 125 | 161 | WALLIGAKPRGPGMERAALLDINGQIFADQGKALNAV | EEEE-------TT--HHHHHHHHHHHHHHHHHHHHHH | bbxxapbxxpxxlbxaaaaaaaaaaaaaaaaaaaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | A - 97 |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | A - 98 |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | G - 99 |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | V - 100 |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | P - 101 |
1a5z_*_93 | 1a5z | * | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | L - 112 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | T - 82 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | A - 83 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | G - 84 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | P - 85 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | R - 86 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | Q - 87 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | I - 103 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | A - 106 |
1lld_A_78 | 1lld | A | NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE | I - 107 |
Clusters included in this Subclass |
CLUSTER: EH.10.12 |