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| Information on SUBCLASS 2.2.12 |
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Subclass Accession number: 4573
Subclass: 2.2.12 
Type: HH alpha-alpha DB: ArchDB95 Image coordinates: 
 Consensus coordinates:
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Number of loops: 4 Average sequence ID (%) : 29.6 +/- 31.5 Average RMSD (Å) : 0.600 +/- 0.141 Consensus geometry
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| Consensus Sequence: | XXpXXX |
| (φψ)-conformation: | aalpaa |
| Pattern: | [s] | [gy] | [AIW] | x | [hl] | [AFL] | x | [AIL] | x | [l] | [KR] | [DW] | [EF] | [DV] | [ags] | [GIV] | [PR] | [ALP] |
| Conservation: | 0.264 | -1.042 | -0.980 | 0.077 | -0.760 | -0.579 | -0.455 | 0.031 | 0.219 | -0.005 | 2.775 | 0.932 | 0.138 | 0.409 | -1.005 | -0.742 | 1.613 | -0.890 |
| Loops included in this Subclass |
| Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
| 1c3d_*_233 | 1c3d | - | 241 | 258 | SYALLALLQLKDFDFVPP | HHHHHHHHHTT-TTTHHH | aaaaaaaaaalxaaaaaa |
| 1hs6_A_532 | 1hs6 | A | 536 | 553 | FRWLRLCIQSKWEDAIPL | HHHHHHHHHTT-TTHHHH | aaaaaaaaaavxaaaaaa |
| 1msw_D_541 | 1msw | D | 541 | 558 | SGIQHFSAMLRDEVGGRA | HHHHHHHHHHT-TTHHHH | aaaaaaaaaalxaaaaaa |
| 1qqf_A_1226 | 1qqf | A | 1234 | 1251 | SYALLALLLLKDFDSVPP | HHHHHHHHHTT-TTSHHH | aaaaaaaaaalxaaaaaa |
| PDB ligands within a cut-off distance of 6 Å in this subclass |
| Loop | PDB | Chain | Ligands | Residue |
| 1hs6_A_532 | 1hs6 | A | IMDIMIDAZOLE | R - 537 |
| Clusters included in this Subclass |
| CLUSTER: HH.5.179 |
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