ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.1.1

Subclass Accession number: 5136
Subclass: 12.1.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 6

Average sequence ID (%) : 63.1 +/- 21.5
Average RMSD (Å) : 0.300 +/- 0.126

Consensus geometry

d (Å): 5

delta (°): 0-45

theta (°): 0-45

rho (°): 180-225

Consensus Sequence:	MhGXTNPApXhPGTIR
(φψ)-conformation:	aaepapaaapppgpaa

Pattern:	[av]	[v]	x	[ast]	[agns]	[r]	x	[im]	[ilm]	[g]	x	[t]	[dn]	[ps]	[al]	[adeq]	[as]	[akl]	[ep]	[g]	[st]	[i]	[r]	[gk]	[d]	[f]
Conservation:	-0.474	0.484	-1.351	-0.643	-0.961	1.013	-1.738	-0.009	-0.291	1.542	-1.451	1.013	0.361	0.001	-0.705	-0.961	-0.310	-1.230	0.028	1.542	-0.000	0.484	1.013	-0.437	1.542	1.542

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ehw_A_83	1ehw	A	83	108	VVRASRAMIGHTDSAEAAPGTIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaepaxaaaxxxgxaaaaa
1hlw_A_87	1hlw	A	87	112	VVASARLMIGVTNPLASAPGSIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaebaxaaaxxpgxaaaaa
1nhk_L_82	1nhk	L	82	107	AVLANRDIMGATNPAQAAEGTIRKDF	HHHHHHHHH--SSGGG--TTSHHHHH	aaaaaaaaaepaxaaaxxxvxaaaaa
1nsq_A_84	1nsq	A	84	109	VVKTGRQMLGATNPADSLPGTIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaexaxaaaxxpgxaaaaa
1nue_A_83	1nue	A	83	108	VVKTGRVMLGETNPADSKPGTIRGDF	HHHHHHHHH--SSGGG--TTSHHHHH	aaaaaaaaaexaxaaaxxpgxaaaaa
1ucn_A_83	1ucn	A	83	108	VVKTGRVMLGETNPADSKPGTIRGDF	HHHHHHHHH--SSGGGS-TTSHHHHH	aaaaaaaaaepaxaaaxxpgxaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1nhk_L_82	1nhk	L	CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	T - 93
1nhk_L_82	1nhk	L	CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	R - 104
1nsq_A_84	1nsq	A	PHSPHOSPHONO GROUP	R - 89
1nsq_A_84	1nsq	A	PHSPHOSPHONO GROUP	R - 106
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	R - 88
1nue_A_83	1nue	A	MGMAGNESIUM ION	R - 88
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	G - 92
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	E - 93
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	T - 94
1nue_A_83	1nue	A	GDPGUANOSINE-5'-DIPHOSPHATE	R - 105
1ucn_A_83	1ucn	A	PO4PHOSPHATE ION	R - 88
1ucn_A_83	1ucn	A	CACALCIUM ION	R - 88
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	R - 88
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	G - 92
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	E - 93
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	T - 94
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	N - 95
1ucn_A_83	1ucn	A	PO4PHOSPHATE ION	R - 105
1ucn_A_83	1ucn	A	ADPADENOSINE-5'-DIPHOSPHATE	R - 105

Clusters included in this Subclass