ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 3.7.1

Subclass Accession number: 7275
Subclass: 3.7.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 20

Average sequence ID (%) : 19.9 +/- 18.2
Average RMSD (Å) : 0.505 +/- 0.219

Consensus geometry

d (Å): 11

delta (°): 0-45

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	hDhXpXX
(φψ)-conformation:	bbaabaa

Pattern:	[acfglvy]	x	x	[ACGLMV]	[DN]	[ILMPV]	[agrst]	[deknqrst]	x	[adegknqs]	[adegqs]	[AFILVW]	[adekqrst]	[akrst]	[acilmvwy]
Conservation:	-0.649	-1.002	-0.657	-0.122	3.123	1.177	-0.285	-0.193	-0.539	-0.312	-0.275	0.401	-0.398	0.026	-0.295

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1e6w_A_58	1e6w	A	60	74	FAPANVTSEKEVQAA	EEE--TT-HHHHHHH	bbpbxaaxaaaaaaa
1ek6_A_61	1ek6	A	62	76	FEEMDILDQGALQRL	EEE--TT-HHHHHHH	bbxbbaaxaaaaaaa
1fmc_A_62	1fmc	A	64	78	ACRCDITSEQELSAL	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1g0o_A_81	1g0o	A	83	97	CVKANVGVVEDIVRM	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1gc0_A_131	1gc0	A	132	146	LRHVDMADLQALEAA	EEEE-TT-HHHHHHH	bbxbxaabaaaaaaa
1geg_A_53	1geg	A	55	69	AVKVDVSDRDQVFAA	EEE--TTSHHHHHHH	xbxbbaabaaaaaaa
1h5q_A_63	1h5q	A	65	79	AYQCDVSNTDIVTKT	EEE--TT-HHHHHHH	xbxbxaaxaaaaaaa
1hdc_A_54	1hdc	A	56	70	YQHLDVTIEEDWQRV	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1i01_A_53	1i01	A	55	69	GLMLNVTDPASIESV	EEE--SS-HHHHHHH	bbxbbaaxaaaaaaa
1itw_A_484	1itw	A	485	499	VFWLDPARAHDAQVI	EEE--TTSHHHHHHH	bxxbxaaxaaaaaaa
1iy8_A_66	1iy8	A	68	82	TTVADVSDEAQVEAY	EEE--TTSHHHHHHH	bbxbxaabaaaaaaa
1jtv_A_59	1jtv	A	61	75	TLQLDVRDSKSVAAA	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1jw7_A_59	1jw7	A	60	74	VYELDVSKEEHFKSL	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1k2w_A_53	1k2w	A	55	69	AIALDVTDQASIDRC	EEE--TT-HHHHHHH	xbxbbaabaaaaaaa
1kew_A_52	1kew	A	54	68	FEHADICDSAEITRI	EEE--TT-HHHHHHH	bbxbbaaxaaaaaaa
1n7h_A_85	1n7h	A	87	101	LHYADLTDASSLRRW	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa
1nff_A_55	1nff	A	57	71	YVHLDVTQPAQWKAA	EEE--TT-HHHHHHH	bbxbxaabaaaaaaa
1oaa_*_63	1oaa	-	66	80	LAAADLGTEAGVQRL	EEE--TTSHHHHHHH	bbxbxaabaaaaaaa
1orr_A_53	1orr	A	54	68	FVHGDIRNKNDVTRL	EEE--TT-HHHHHHH	bbxbbaaxaaaaaaa
1qsg_A_60	1qsg	A	60	74	VLQCDVAEDASIDTM	EEE--TT-HHHHHHH	bbxbbaabaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1e6w_A_58	1e6w	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 63
1e6w_A_58	1e6w	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	N - 64
1e6w_A_58	1e6w	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 65
1e6w_A_58	1e6w	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 66
1ek6_A_61	1ek6	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	M - 65
1ek6_A_61	1ek6	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	D - 66
1ek6_A_61	1ek6	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	I - 67
1ek6_A_61	1ek6	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	L - 68
1fmc_A_62	1fmc	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	C - 67
1fmc_A_62	1fmc	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 68
1fmc_A_62	1fmc	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 69
1fmc_A_62	1fmc	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 70
1g0o_A_81	1g0o	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	A - 86
1g0o_A_81	1g0o	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	N - 87
1g0o_A_81	1g0o	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	V - 88
1g0o_A_81	1g0o	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 89
1geg_A_53	1geg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 58
1geg_A_53	1geg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 59
1geg_A_53	1geg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 60
1geg_A_53	1geg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	S - 61
1geg_A_53	1geg	A	GLCGLUCOSE	R - 63
1geg_A_53	1geg	A	GLCGLUCOSE	D - 64
1geg_A_53	1geg	A	GLCGLUCOSE	Q - 65
1geg_A_53	1geg	A	GLCGLUCOSE	F - 67
1geg_A_53	1geg	A	GLCGLUCOSE	A - 68
1h5q_A_63	1h5q	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	C - 68
1h5q_A_63	1h5q	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 69
1h5q_A_63	1h5q	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	V - 70
1h5q_A_63	1h5q	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	S - 71
1iy8_A_66	1iy8	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 71
1iy8_A_66	1iy8	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 72
1iy8_A_66	1iy8	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 73
1iy8_A_66	1iy8	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	S - 74
1jw7_A_59	1jw7	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	L - 63
1jw7_A_59	1jw7	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 64
1jw7_A_59	1jw7	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	S - 66
1kew_A_52	1kew	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 57
1kew_A_52	1kew	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 58
1kew_A_52	1kew	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 59
1kew_A_52	1kew	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	C - 60
1n7h_A_85	1n7h	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	A - 90
1n7h_A_85	1n7h	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 91
1n7h_A_85	1n7h	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	L - 92
1n7h_A_85	1n7h	A	NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	T - 93
1nff_A_55	1nff	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	L - 60
1nff_A_55	1nff	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	D - 61
1nff_A_55	1nff	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	V - 62
1nff_A_55	1nff	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 63
1oaa_*_63	1oaa	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	A - 69
1oaa_*_63	1oaa	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	D - 70
1oaa_*_63	1oaa	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	L - 71
1oaa_*_63	1oaa	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	G - 72
1oaa_*_63	1oaa	*	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	T - 73
1orr_A_53	1orr	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	G - 57
1orr_A_53	1orr	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	R - 60
1qsg_A_60	1qsg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	C - 63
1qsg_A_60	1qsg	A	GLCGLUCOSE	A - 66
1qsg_A_60	1qsg	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 66

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1e6w_A_58	1e6w	A	AC1NAD BINDING SITE FOR CHAIN A	A - 63
1e6w_A_58	1e6w	A	AC1NAD BINDING SITE FOR CHAIN A	N - 64
1h5q_A_63	1h5q	A	AC1NAP BINDING SITE FOR CHAIN A	C - 68
1h5q_A_63	1h5q	A	AC1NAP BINDING SITE FOR CHAIN A	D - 69

Clusters included in this Subclass

CLUSTER: EH.4.8