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Information on SUBCLASS 6.1.2
Subclass Accession number: 8633
Subclass: 6.1.2 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 17

Average sequence ID (%) : 23.7 +/- 23.3
Average RMSD (Å) : 0.747 +/- 0.177

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXGhXXXphX
(φψ)-conformation: aagppaaabb
Pattern: [egqrst]xx[afgilt]xxxx[GK][AFILV][dehpqs]x[adenq][DEKQR][ILV]x[AGILY]
Conservation:-0.481-0.419-0.769-0.884-0.746-0.466-1.1310.0252.7410.6190.180-0.2340.0450.9421.645-0.443-0.624
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aj0_*_1571aj0   -168184QIARCEQAGIAKEKLLLHHHHHHHTT--GGGEEEaaaaaaaagxpaaaxbb
1cqx_A_3711cqx   A377393QHDALKNLGIHEARIHYHHHHHHHTT--GGGEEEaaaaaaaavxxaaabbb
1eg7_A_10191eg7   A10191035VMELARGLGIQEDEVELHHHHHHTTT--GGGEEEaaaaaaaavxxaaabbx
1eye_A_1491eye   A160176SVADAVAAGVDPARLVLHHHHHHHTT--GGGEEEaaaaaaaagxxaaaxbx
1f3t_A_921f3t   A94110EIQRVRGIGVPPEKIIYHHHHHHHTT--GGGEEEaaaaaaaavxxaaabbx
1gv0_A_1441gv0   A152168RSFIAMELGVSMQDVTAHHHHHHHHT--GGGEEEaaaaaaaavbxaaaxbb
1gv1_A_1211gv1   A125141THVAWVRSGLPKERVIGHHHHHHHHT--GGGEEEaaaaaaaavxxaaabbb
1hye_A_1251hye   A129145TYKALVDSKFERNQVFGHHHHHHHH---TTSEEEaaaaaaaavxxaaabbb
1hyh_A_1451hyh   A149165TALFQHVTGFPAHKVIGHHHHHHHH---GGGEEEaaaaaaaavxwaaabbb
1i0z_A_1401i0z   A144160TYVTWKLSGLPKHRVIGHHHHHHHH---GGGEEEaaaaaaaavxxaaabbx
1itx_A_3141itx   A317333GAQGHLDAGVPAAKLVLHHHHHHHHT--GGGEEEaaaaaaaagxxaaabbx
1ldg_*_1421ldg   -146162VQLLHQHSGVPKNKIIGHHHHHHHH---GGGEEEaaaaaaaavxxaaabbb
1ldn_A_1401ldn   A144160TYATWKFSGLPHERVIGHHHHHHHHT--GGGEEEaaaaaaaavxxaaabxb
1lld_A_1271lld   A131147THVAQKLTGLPENQIFGHHHHHHHHT--TTSEEEaaaaaaaavxwaaabbb
1ur5_A_1221ur5   A126142TYLAAEVSGFPKERVIGHHHHHHHH---GGGEEEaaaaaaaavxxaaabbb
4pro_C_1374pro   C140156GVDFVALSGADSAQVRIHHHHHHHTT--GGGEEEaaaaaaaalxpaaabbx
9ldt_A_1429ldt   A146162TYVAWKISGFPKNRVIGHHHHHHHH---TTSEEEaaaaaaaavxwaaabbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aj0_*_1571aj0   *     PH22-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE D - 185
1cqx_A_3711cqx   A     DGG1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL I - 371
1cqx_A_3711cqx   A     DGG1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL M - 374
1cqx_A_3711cqx   A     DGG1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL R - 375
1cqx_A_3711cqx   A     DGG1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL Y - 393
1eye_A_1491eye   A     PMMPTERIN-6-YL-METHYL-MONOPHOSPHATE D - 177
1gv0_A_1441gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 146
1gv0_A_1441gv0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 150
1hye_A_1251hye   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 125
1hyh_A_1451hyh   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 145
1i0z_A_1401i0z   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE V - 140
1ldg_*_1421ldg   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 142
1ldg_*_1421ldg   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 162
1ldn_A_1401ldn   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 140
1lld_A_1271lld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 127
1ur5_A_1221ur5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 122
1ur5_A_1221ur5   A     CDCADMIUM ION L - 122
1ur5_A_1221ur5   A     CDCADMIUM ION D - 123
1ur5_A_1221ur5   A     CDCADMIUM ION A - 124
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gv0_A_1441gv0   A NAANAD BINDING SITE FOR CHAIN AL - 146
1ur5_A_1221ur5   A AC9CL BINDING SITE FOR CHAIN AD - 123
1ur5_A_1221ur5   A AC9CL BINDING SITE FOR CHAIN AA - 124

Clusters included in this Subclass
CLUSTER: HE.5.51
CLUSTER: HE.6.13
CLUSTER: HE.7.3
CLUSTER: HE.8.85