ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 16.2.1

Subclass Accession number: 9254
Subclass: 16.2.1

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 5

Average sequence ID (%) : 20.5 +/- 17.9
Average RMSD (Å) : 1.200 +/- 0.485

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	pXpphpGXhhhXhGhXhphX
(φψ)-conformation:	aappaagpbbabpgpppbaa

Pattern:	[AILT]	x	[EQRSW]	[WY]	[IL]	[acly]	[EHRS]	[cers]	[KMQ]	[nqrs]	x	[DES]	[GN]	[GST]	[FILW]	[agl]	[glm]	x	[APV]	[EG]	[GKLM]	[ep]	[APSV]	[DH]	[GLV]	[dgr]	[STY]	[AST]	[FIWY]	[CEW]	[AGV]	[AILY]	[ASV]	[ASV]	[AL]	[ckv]	[ILY]
Conservation:	-0.290	-1.339	-0.677	3.070	1.346	-1.087	-0.134	-1.276	0.665	-0.803	-0.670	1.183	1.964	0.390	-0.023	-0.895	-1.026	-1.181	0.373	1.339	-1.085	-0.424	-0.423	1.288	-0.809	-1.036	-0.168	0.728	0.676	0.353	-0.122	-0.387	0.226	0.047	0.629	-0.806	0.383

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1dce_B_212	1dce	B	215	251	LGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKI	HHHHHHTTB-TTS-B-SSTT----HHHHHHHHHHHHH	aaaaaaaaxxaavxbbabpvbxwbaaaaaaaaaaaaa
1ld8_B_674	1ld8	B	677	713	LLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASL	HHHHHHHHB-TTS-BBSSTT--B-HHHHHHHHHHHHH	aaaaaaaaxxaavxbxabpvbxbbaaaaaaaaaaaaa
1ld8_B_725	1ld8	B	725	761	TAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVI	HHHHHHHHB-TTSSB-SSTTS---HHHHHHHHHHHHH	aaaaaaaaxbaagxbbabpgxpxbaaaaaaaaaaaaa
1n4p_B_193	1n4p	B	196	232	AISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCL	HHHHHHHTB-TTSSBBSSTTS-B-HHHHHHHHHHHHH	aaaaaaaaxxaavxbbabpgxxxbaaaaaaaaaaaaa
2sqc_A_58	2sqc	A	64	100	IRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKY	HHHHHHHHS-TTS---SSTT----HHHHHHHHHHHHH	aaaaaaaaxxaavbbbabxvxxpbaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dce_B_212	1dce	B	ZNZINC ION	D - 238
1dce_B_212	1dce	B	ZNZINC ION	V - 239
1dce_B_212	1dce	B	ZNZINC ION	C - 240
1dce_B_212	1dce	B	ZNZINC ION	Y - 241
1dce_B_212	1dce	B	ZNZINC ION	W - 244
1ld8_B_674	1ld8	B	FPPFARNESYL DIPHOSPHATE	M - 693
1ld8_B_674	1ld8	B	FPPFARNESYL DIPHOSPHATE	R - 702
1ld8_B_674	1ld8	B	U49(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1, 6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE	R - 702
1ld8_B_674	1ld8	B	FPPFARNESYL DIPHOSPHATE	Y - 705
1ld8_B_674	1ld8	B	FPPFARNESYL DIPHOSPHATE	C - 706
1ld8_B_725	1ld8	B	SUCSUCROSE	A - 730
1ld8_B_725	1ld8	B	SUCSUCROSE	R - 731
1ld8_B_725	1ld8	B	SUCSUCROSE	C - 732
1ld8_B_725	1ld8	B	SUCSUCROSE	Q - 733
1ld8_B_725	1ld8	B	SUCSUCROSE	N - 734
1ld8_B_725	1ld8	B	SUCSUCROSE	W - 735
1ld8_B_725	1ld8	B	SUCSUCROSE	E - 736
1ld8_B_725	1ld8	B	SUCSUCROSE	G - 737
1ld8_B_725	1ld8	B	SUCSUCROSE	G - 738
1ld8_B_725	1ld8	B	FPPFARNESYL DIPHOSPHATE	H - 748
1ld8_B_725	1ld8	B	U49(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1, 6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE	H - 748
1ld8_B_725	1ld8	B	FPPFARNESYL DIPHOSPHATE	G - 749
1ld8_B_725	1ld8	B	FPPFARNESYL DIPHOSPHATE	G - 750
1ld8_B_725	1ld8	B	FPPFARNESYL DIPHOSPHATE	Y - 751
1ld8_B_725	1ld8	B	U49(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1, 6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE	Y - 751
1ld8_B_725	1ld8	B	FPPFARNESYL DIPHOSPHATE	C - 754
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	Q - 212
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	H - 219
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	G - 220
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	G - 221
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	S - 222
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	F - 224
1n4p_B_193	1n4p	B	GRGGERANYLGERANYL DIPHOSPHATE	C - 225

Clusters included in this Subclass

CLUSTER: HH.17.0