PDB: 1j4a Compound: d-lactate dehydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 2002-05-29 Resolution [Å]: 1.90 R-Factor: 0.204

CHAIN: A SWISS-PROT/TREMBL: P26297    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.28 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis    CHAIN: B SWISS-PROT/TREMBL: P26297    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.28 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis    CHAIN: C SWISS-PROT/TREMBL: P26297    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.28 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis    CHAIN: D SWISS-PROT/TREMBL: P26297    KEYWORD: 3D-structure    NAD    Oxidoreductase    EC: 1.1.1.28 SCOP: c.2.1.4 Alpha and beta proteins (a/b)    NAD(P)-binding Rossmann-fold domains    NAD(P)-binding Rossmann-fold domains    Formate/glycerate dehydrogenases, NAD-domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus SCOP: c.23.12.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Formate/glycerate dehydrogenase catalytic domain-like    Formate/glycerate dehydrogenases, substrate-binding domain    D-lactate dehydrogenase    Lactobacillus helveticus GO:  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor    L-serine biosynthesis

Image Source: PDB

Loops in ArchDB95 clusters

1j4a_A_148 - EH => SUBCLASS : 3.5.1
1j4a_A_3 - EH => SUBCLASS : 3.6.5
1j4a_A_171 - EH => SUBCLASS : 4.4.1
1j4a_A_49 - EH => SUBCLASS : 5.31.1
1j4a_A_229 - EH => SUBCLASS : 8.17.1
1j4a_A_202 - EH => SUBCLASS : 13.3.1
1j4a_A_181 - HH => SUBCLASS : 6.52.1
1j4a_A_86 - HE => SUBCLASS : 2.1.3
1j4a_A_193 - HE => SUBCLASS : 2.2.1
1j4a_A_242 - HE => SUBCLASS : 2.4.1
1j4a_A_242 - HE => SUBCLASS : 2.4.4
1j4a_A_60 - HE => SUBCLASS : 3.1.1
1j4a_A_60 - HE => SUBCLASS : 3.3.1
1j4a_A_281 - HE => SUBCLASS : 3.6.1
1j4a_A_219 - HE => SUBCLASS : 5.4.1

Loops in ArchDB-EC clusters

1j4a_A_181 - HH => SUBCLASS : 6.20.1

Loops not clustered in ArchDB

1j4a_A_28 - AR
1j4a_A_28 - AR
1j4a_A_73 - EH
1j4a_A_292 - EH
1j4a_A_254 - EH
1j4a_A_95 - EH
1j4a_A_14 - HE
1j4a_A_156 - HE
1j4a_A_122 - HE
1j4a_A_104 - HH

1j49 A - percentage of sequence identity: 99
1j49 B - percentage of sequence identity: 99
1j4a A - percentage of sequence identity: 100
1j4a B - percentage of sequence identity: 100
1j4a C - percentage of sequence identity: 100
1j4a D - percentage of sequence identity: 100
2dld A - percentage of sequence identity: 84
2dld B - percentage of sequence identity: 84