PDB: 2frv Compound: periplasmic hydrogenase Classification: OXIDOREDUCTASE Entry date in PDB: 1998-06-17 Resolution [Å]: 2.54 R-Factor: 0.202

CHAIN: A SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone    CHAIN: B SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: C SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone    CHAIN: D SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: E SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone    CHAIN: F SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: G SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone    CHAIN: H SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: I SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone    CHAIN: J SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: L SWISS-PROT/TREMBL: P12944    KEYWORD: 3D-structure    Metal-binding    Nickel    Oxidoreductase    Periplasmic    EC: 1.12.2.1 SCOP: e.18.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Nickel-iron hydrogenase, large subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase activity    nickel ion binding    electron transport    CHAIN: S SWISS-PROT/TREMBL: P12943    KEYWORD: 3D-structure    3Fe-4S    4Fe-4S    Iron-sulfur    Oxidoreductase    Periplasmic    Signal    EC: 1.12.2.1 SCOP: e.19.1.1 Multi-domain proteins (alpha and beta)    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Nickel-iron hydrogenase, small subunit    Desulfovibrio gigas GO:  ferredoxin hydrogenase complex    ferredoxin hydrogenase activity    iron ion binding    NADH dehydrogenase (ubiquinone) activity    electron transport    mitochondrial electron transport, NADH to ubiquinone

Image Source: PDB

Loops in ArchDB-EC clusters

2frv_A_228 - HH => SUBCLASS : 22.1.1

Loops not clustered in ArchDB

2frv_A_68 - AR
2frv_B_307 - AR
2frv_B_31 - EH
2frv_A_143 - EH
2frv_A_105 - EH
2frv_A_90 - EH
2frv_A_41 - EH
2frv_A_8 - EH
2frv_B_477 - EH
2frv_B_227 - EH
2frv_B_359 - EH
2frv_B_21 - HA
2frv_B_223 - HA
2frv_B_280 - HA
2frv_B_301 - HA
2frv_B_319 - HA
2frv_B_452 - HA
2frv_B_464 - HA
2frv_A_86 - HA
2frv_B_8 - HA
2frv_B_188 - HE
2frv_A_131 - HE
2frv_A_92 - HE
2frv_A_54 - HE
2frv_A_32 - HE
2frv_B_407 - HE
2frv_B_257 - HE
2frv_B_371 - HH
2frv_B_45 - HH
2frv_B_54 - HH
2frv_B_71 - HH
2frv_A_206 - HH
2frv_A_191 - HH
2frv_A_184 - HH
2frv_B_148 - HH
2frv_B_236 - HH
2frv_B_90 - HH
2frv_B_384 - HH
2frv_B_485 - HH
2frv_B_501 - HH
2frv_B_518 - HH
2frv_A_19 - HH
2frv_A_110 - HH
2frv_A_152 - HH
2frv_A_177 - HH
2frv_B_131 - HH

1e3d A - percentage of sequence identity: 65
1e3d B - percentage of sequence identity: 62
1e3d D - percentage of sequence identity: 62
1frf L - percentage of sequence identity: 65
1frf S - percentage of sequence identity: 68
1frv B - percentage of sequence identity: 99
1frv D - percentage of sequence identity: 99
1h2a L - percentage of sequence identity: 68
1h2r L - percentage of sequence identity: 68
1ubh L - percentage of sequence identity: 69
1ubj L - percentage of sequence identity: 69
1ubk L - percentage of sequence identity: 69
1ubk S - percentage of sequence identity: 67
1ubl L - percentage of sequence identity: 69
1ubl S - percentage of sequence identity: 67
1ubm L - percentage of sequence identity: 69
1ubo L - percentage of sequence identity: 69
1ubr L - percentage of sequence identity: 69
1ubt L - percentage of sequence identity: 69
1ubu L - percentage of sequence identity: 69
1wuh L - percentage of sequence identity: 69
1wui L - percentage of sequence identity: 69
1wuj L - percentage of sequence identity: 69
1wuk L - percentage of sequence identity: 69
1wul L - percentage of sequence identity: 69
1yq9 H - percentage of sequence identity: 99
1yq9 I - percentage of sequence identity: 99
1yqw Q - percentage of sequence identity: 65
1yqw R - percentage of sequence identity: 65
1yqw S - percentage of sequence identity: 65
1yrq H - percentage of sequence identity: 65
1yrq I - percentage of sequence identity: 65
1yrq J - percentage of sequence identity: 65
1yrq K - percentage of sequence identity: 65
1yrq M - percentage of sequence identity: 65
1yrq N - percentage of sequence identity: 65
2frv B - percentage of sequence identity: 100
2frv D - percentage of sequence identity: 100
2frv F - percentage of sequence identity: 100
2frv H - percentage of sequence identity: 100
2frv J - percentage of sequence identity: 100
2frv L - percentage of sequence identity: 100