ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.2.6

Subclass Accession number: 1004
Subclass: 1.2.6

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
SCOP : 52539 (>75 %) 52540 (>75 %) 53747 (>75 %) 53748 (>75 %) 53749 (>75 %)

Number of loops: 12

Average sequence ID (%) : 17.5 +/- 17.0
Average RMSD (Å) : 0.558 +/- 0.188

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 135-180

rho (°): 225-270

Consensus Sequence:	hXGpX
(φψ)-conformation:	bbeaa

Pattern:	[FILVY]	[AFGIKLV]	[ags]	x	[GS]	[drsty]	[egpqs]	[CGILVY]	x	x	x	x	[ekst]	x	[afgil]
Conservation:	0.941	-0.136	0.820	-0.654	3.131	-0.195	-0.424	-0.524	-0.634	-0.487	-0.530	-0.283	0.114	-0.710	-0.429

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1f0x_A_390	1f0x	A	394	408	LKMAGDGVGEAKSWL	EEE-TTHHHHHHHHH	xxbbeaaaaaaaaaa
1g0u_J_124	1g0u	J	124	138	YGAHGYSGFYTFSLL	EEE-TTHHHHHHHHH	bbbbeaaaaaaaaaa
1gpu_A_557	1gpu	A	559	573	LVATGSEVSLSVEAA	EEE-THHHHHHHHHH	bbbbeaaaaaaaaaa
1j5x_A_42	1j5x	A	45	59	FVGCGSSYNLALTIS	EEESTHHHHHHHHHH	bbbbeaaaaaaaaaa
1kek_A_271	1kek	A	273	287	IVSMGSSCETIEEVI	EEE-STHHHHHHHHH	xbbbeaaaaaaaaaa
1l8a_A_724	1l8a	A	728	742	LLGSGSILRHVREAA	EEE-GGGHHHHHHHH	bbbbeaaaaaaaaaa
1moq_*_294	1moq	-	297	311	ILACGTSYNSGMVSR	EEE-HHHHHHHHHHH	bbbbeaaaaaaaaaa
1ni4_B_207	1ni4	B	209	223	VVSHSRPVGHCLEAA	EEE-STHHHHHHHHH	bbbbeaaaaaaaaaa
1nri_A_71	1nri	A	73	87	YIGAGTSGRLGVLDA	EEESHHHHHHHHHHH	bbbbeaaaaaaaaaa
1o7q_A_129	1o7q	A	133	147	VFAVGRYIEHYLEEF	EEE-TTHHHHHHHHH	bbbbeaaaaaaaaaa
1ols_B_222	1ols	B	224	238	LVAWGTQVHVIREVA	EEE-TTHHHHHHHHH	bbbbeaaaaaaaaaa
1r1d_A_87	1r1d	A	89	103	VAGLSLGGVFSLKLG	EEE-THHHHHHHHHH	bbbbeaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	C - 48
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	S - 50
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	S - 51
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	L - 54
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	T - 57
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	I - 58
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	Y - 60
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	Y - 61
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	F - 62
1j5x_A_42	1j5x	A	MSESELENOMETHIONINE	V - 65
1moq_*_294	1moq	*	GLPGLUCOSAMINE 6-PHOSPHATE	C - 300
1moq_*_294	1moq	*	GLPGLUCOSAMINE 6-PHOSPHATE	G - 301
1moq_*_294	1moq	*	GLPGLUCOSAMINE 6-PHOSPHATE	T - 302
1moq_*_294	1moq	*	GLPGLUCOSAMINE 6-PHOSPHATE	S - 303
1moq_*_294	1moq	*	MPD2-METHYL-2,4-PENTANEDIOL	Y - 304
1moq_*_294	1moq	*	MPD2-METHYL-2,4-PENTANEDIOL	N - 305
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	T - 208
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	V - 210
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	S - 211
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	H - 212
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	S - 213
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	R - 214
1ni4_B_207	1ni4	B	MSESELENOMETHIONINE	V - 216
1nri_A_71	1nri	A	MSESELENOMETHIONINE	L - 71
1nri_A_71	1nri	A	MSESELENOMETHIONINE	I - 72
1nri_A_71	1nri	A	MSESELENOMETHIONINE	D - 86
1nri_A_71	1nri	A	MSESELENOMETHIONINE	C - 90
1nri_A_71	1nri	A	MSESELENOMETHIONINE	P - 92
1nri_A_71	1nri	A	MSESELENOMETHIONINE	T - 93
1nri_A_71	1nri	A	MSESELENOMETHIONINE	F - 94
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	V - 133
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	F - 134
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	A - 135
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	V - 136
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	G - 137
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	R - 138
1o7q_A_129	1o7q	A	MNMANGANESE (II) ION	Y - 139
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	Y - 139
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	I - 140
1o7q_A_129	1o7q	A	GOLGLYCEROL	E - 141
1o7q_A_129	1o7q	A	GOLGLYCEROL	H - 142
1o7q_A_129	1o7q	A	GOLGLYCEROL	Y - 143
1o7q_A_129	1o7q	A	UDPURIDINE-5'-DIPHOSPHATE	Y - 143
1o7q_A_129	1o7q	A	GOLGLYCEROL	E - 146
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	A - 90
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	G - 91
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	L - 92
1r1d_A_87	1r1d	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	L - 92
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	S - 93
1r1d_A_87	1r1d	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	S - 93
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	L - 94
1r1d_A_87	1r1d	A	EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	L - 94
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	G - 96
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	V - 97
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	L - 100
1r1d_A_87	1r1d	A	MSESELENOMETHIONINE	L - 102

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1o7q_A_129	1o7q	A	AC6UDP BINDING SITE FOR CHAIN A	F - 134
1o7q_A_129	1o7q	A	AC6UDP BINDING SITE FOR CHAIN A	A - 135
1o7q_A_129	1o7q	A	AC6UDP BINDING SITE FOR CHAIN A	Y - 139
1o7q_A_129	1o7q	A	AC1GOL BINDING SITE FOR CHAIN A	H - 142
1o7q_A_129	1o7q	A	AC1GOL BINDING SITE FOR CHAIN A	Y - 143
1o7q_A_129	1o7q	A	AC1GOL BINDING SITE FOR CHAIN A	E - 146

Clusters included in this Subclass