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Information on SUBCLASS 6.1.1
Subclass Accession number: 43
Subclass: 6.1.1
Type: EH beta-alpha
DB: ArchDB-KI
 Number of loops: 26

Average sequence ID (%) : 50.5 +/- 3.3
Average RMSD (Å) : 0.75 +/- 0.76

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: hXGhXGXGKX
(φψ)-conformation: bbepplagaa
Pattern: {AFILMVY}[ILMV]x[G][AGILPV]{DPS}{AG}x[G][K]x[TY]x{ACGL}
Conservation:-0.5810.207-0.9151.832-0.940-0.611-0.160-0.7271.8321.380-0.4220.482-0.691-0.684
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ak2_*_181ak2   -2033VLLGPPGAGKGTQAEEE--TTSSHHHHHbbbbxxvagaaaaa
1ake_A_21ake   A417ILLGAPGAGKGTQAEEEESTTSSHHHHHbbbeppvagaaaaa
1aky_*_61aky   -821VLIGPPGAGKGTQAEEE--TTSSHHHHHbbbbxpvagaaaaa
1ank_A_31ank   A417ILLGAPGAGKGTQAEEEE-TTSSHHHHHbxbexxvagaaaaa
1cke_A_71cke   A922TIDGPSGAGKGTLCEEE--TTSSHHHHHbbbexxvagaaaaa
1dek_A_21dek   A518FLSGVKRSGKDTTAEEE--TTSSHHHHHbxbexplagaaaaa
1dvr_A_61dvr   A821VLIGPPGAGKGTQAEEE--TTSSHHHHHbbbepxvagaaaaa
1gky_*_41gky   -518VISGPSGTGKSTLLEEE--TTSSHHHHHxbbexxgavaaaaa
1kim_A_481kim   A5366YIDGPHGMGKTTTTEE-S-SSSSHHHHHbxbexxvagaaaaa
1nks_A_21nks   A518IVTGIPGVGKSTVLEEEE-TTS-HHHHHbxbbxpvavaaaaa
1qf9_A_71qf9   A1023FVLGGPGSGKGTQCEEEESTTSSHHHHHxbbexpvagaaaaa
1qhi_A_481qhi   A5366YIDGPHGMGKTTTTEE-SSTTSSHHHHHbxbexxvagaaaaa
1shk_A_51shk   A619FMVGARGCGKTTVGEEE--TTS-HHHHHxbbexpvavaaaaa
1uke_*_71uke   -1023FVLGGPGSGKGTQCEEE-STTSSHHHHHxbbexxvagaaaaa
1uky_*_171uky   -2033FVLGGPGAGKGTQCEEE-STTSSHHHHHxbbexxvagaaaaa
1ukz_*_171ukz   -2033FVLGGPGAGKGTQCEEE-STTSSHHHHHxbbexxvagaaaaa
1vtk_*_481vtk   -5366YIDGPHGMGKTTTTEE-SSSSSSHHHHHbxbepxvagaaaaa
1zak_A_81zak   A922MISGAPASGKGTQCEEEESTTSSHHHHHbbbexpvagaaaaa
1zip_*_21zip   -417VLMGLPGAGKGTQAEEE-STTSSHHHHHbbbbxpvagaaaaa
2ak3_A_72ak3   A922AIMGAPGSGKGTVSEEE--TTSSHHHHHbbbeppvavaaaaa
2cmk_A_72cmk   A922TIDGPSGAGKGTLCEEE--TTSSHHHHHbbbexxvagaaaaa
2eck_A_32eck   A417ILLGAPGAGKGTQAEEEE-TTSSHHHHHbbbbpxvavaaaaa
2ki5_A_482ki5   A5366YIDGPHGMGKTTTTEE-SSSSSSHHHHHxxbexxvagaaaaa
3adk_*_103adk   -1225FVVGGPGSGKGTQCEEEE-TTSSHHHHHxbbbxxvavaaaaa
3bif_A_393bif   A4255VMVGLPARGKTYISEEE--TTSSHHHHHbxbexxvavaaaaa
3tmk_A_73tmk   A922LIEGLDRTGKTTQCEEEE-SSSSHHHHHbbbexxlavaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 7
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 8
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 9
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 10
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 11
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 12
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 13
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 15
1ake_A_21ake   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 16
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 11
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 12
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 13
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1aky_*_61aky   *     IMDIMIDAZOLE G - 14
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 15
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 16
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 17
1aky_*_61aky   *     IMDIMIDAZOLE K - 17
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 18
1aky_*_61aky   *     IMDIMIDAZOLE G - 18
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 19
1aky_*_61aky   *     IMDIMIDAZOLE T - 19
1aky_*_61aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 20
1aky_*_61aky   *     IMDIMIDAZOLE A - 21
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 7
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 8
1ank_A_31ank   A     AMPADENOSINE MONOPHOSPHATE P - 9
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER P - 9
1ank_A_31ank   A     AMPADENOSINE MONOPHOSPHATE G - 10
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 10
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 11
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 12
1ank_A_31ank   A     AMPADENOSINE MONOPHOSPHATE K - 13
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 13
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER G - 14
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 15
1ank_A_31ank   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Q - 16
1dek_A_21dek   A     DGP2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE K - 10
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER G - 11
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER P - 12
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER P - 13
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER G - 14
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER A - 15
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER G - 16
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER K - 17
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER G - 18
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER T - 19
1dvr_A_61dvr   A     ATFPHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER Q - 20
1gky_*_41gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE G - 8
1gky_*_41gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE S - 10
1gky_*_41gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE K - 14
1kim_A_481kim   A     THMTHYMIDINE H - 58
1kim_A_481kim   A     THMTHYMIDINE K - 62
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 13
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 13
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 14
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 14
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION P - 15
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE P - 15
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE P - 15
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 16
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 16
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE G - 16
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION S - 17
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE S - 17
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 18
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION K - 19
1qf9_A_71qf9   A     MGMAGNESIUM ION K - 19
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE K - 19
1qf9_A_71qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE K - 19
1qf9_A_71qf9   A     ALFTETRAFLUOROALUMINATE ION G - 20
1qf9_A_71qf9   A     MGMAGNESIUM ION G - 20
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 20
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE T - 21
1qf9_A_71qf9   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 22
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE G - 13
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE G - 14
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE P - 15
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE G - 16
1uke_*_71uke   *     MGMAGNESIUM ION G - 16
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE S - 17
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE G - 18
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE K - 19
1uke_*_71uke   *     MGMAGNESIUM ION K - 19
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE G - 20
1uke_*_71uke   *     MGMAGNESIUM ION G - 20
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE T - 21
1uke_*_71uke   *     MGMAGNESIUM ION T - 21
1uke_*_71uke   *     UP5P1-(ADENOSINE-5'-P5-(URIDINE-5')PENTAPHOSPHATE Q - 22
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE G - 23
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE G - 24
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE P - 25
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE G - 26
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE A - 27
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE G - 28
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE K - 29
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE G - 30
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE T - 31
1uky_*_171uky   *     ADPADENOSINE-5'-DIPHOSPHATE Q - 32
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE G - 23
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE G - 24
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE P - 25
1ukz_*_171ukz   *     AMPADENOSINE MONOPHOSPHATE P - 25
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE G - 26
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE A - 27
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE G - 28
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE K - 29
1ukz_*_171ukz   *     AMPADENOSINE MONOPHOSPHATE K - 29
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE G - 30
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE T - 31
1ukz_*_171ukz   *     ADPADENOSINE-5'-DIPHOSPHATE Q - 32
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE G - 56
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE P - 57
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE P - 57
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE H - 58
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE H - 58
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE G - 59
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE G - 59
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE M - 60
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE M - 60
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE G - 61
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE K - 62
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE K - 62
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE T - 63
1vtk_*_481vtk   *     TMPTHYMIDINE-5'-PHOSPHATE T - 63
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE T - 64
1vtk_*_481vtk   *     ADPADENOSINE-5'-DIPHOSPHATE T - 65
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 12
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 13
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 14
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 15
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE S - 16
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 17
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 18
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 19
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 20
1zak_A_81zak   A     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 21
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 7
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 8
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE P - 9
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 10
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE A - 11
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 12
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 13
1zip_*_21zip   *     MNMANGANESE (II) ION K - 13
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 14
1zip_*_21zip   *     MNMANGANESE (II) ION G - 14
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 15
1zip_*_21zip   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 16
2ak3_A_72ak3   A     AMPADENOSINE MONOPHOSPHATE K - 18
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE G - 7
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE A - 8
2eck_A_32eck   A     AMPADENOSINE MONOPHOSPHATE P - 9
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE P - 9
2eck_A_32eck   A     AMPADENOSINE MONOPHOSPHATE G - 10
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE G - 10
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE A - 11
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE G - 12
2eck_A_32eck   A     AMPADENOSINE MONOPHOSPHATE K - 13
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE K - 13
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE G - 14
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE T - 15
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 16
2eck_A_32eck   A     ADPADENOSINE-5'-DIPHOSPHATE A - 17
2ki5_A_482ki5   A     AC29-HYROXYETHOXYMETHYLGUANINE H - 58
2ki5_A_482ki5   A     AC29-HYROXYETHOXYMETHYLGUANINE K - 62
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE G - 12
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE L - 13
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE D - 14
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE R - 15
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE T - 16
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE G - 17
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE K - 18
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE T - 19
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE T - 20
3tmk_A_73tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE Q - 21
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1shk_A_51shk   A POPA WALKER TYPE A MOTIF FORMS THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.G - 9
1shk_A_51shk   A POPA WALKER TYPE A MOTIF FORMS THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.G - 14
1shk_A_51shk   A POPA WALKER TYPE A MOTIF FORMS THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.K - 15
1shk_A_51shk   A POPA WALKER TYPE A MOTIF FORMS THE P-LOOP WHICH IS THE BINDING SITE FOR THE PHOSPHATES OF ATP.T - 16
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.G - 45
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.L - 46
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.P - 47
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.A - 48
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.R - 49
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.G - 50
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.K - 51
3bif_A_393bif   A S1WALKER-A MOTIF (GXXGXGKT), PART OF THE CLASSICAL MONONUCLEOTIDE BINDING MOTIF.T - 52
Bibliographic annotations
LoopPDBChainAnnotationResidue
1ake_A_21ake   RefC.W.MUELLER,G.E.SCHULZ. STRUCTURE OF THE COMPLEX BETWEEN ADENYLATE KINASE FROM ESCHERICHIA COLI AND THE INHIBITOR AP=5=A REFINED AT 1.9 ANGSTROMS RESOLUTION: A MODEL FOR A CATALYTIC TRANSITION STATE  J.MOL.BIOL. v.224;159,1992AP-LOOPK - 13
1dek_A_21dek   RefA.TEPLYAKOV,P.SEBASTIAO,G.OBMOLOVA,A.PERRAKIS,G.S.BRUSH,M.J.BESSMAN,K.S.WILSON. CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 DEOXYNUCLEOTIDE KINASE WITH ITS SUBSTRATES DGMP AND ATP  EMBO J. v.15;3487,1996ANMP BINDING RESIDUEK - 10
1kim_A_481kim   RefJ.N.CHAMPNESS,M.S.BENNETT,F.WIEN,R.VISSE,W.C.SUMMERS,P.HERDEWIJN,E.DECLERCQ,T.OSTROWSKI,R.L.JARVEST,M.R.SANDERSON. EXPLORATION OF THE ACTIVE SITE OF HERPES SIMPLEX VIRUS THYMIDINE KINASE BY X-RAY CRYSTALLOGRAPHY OF THE ENZYME IN COMPLEX WITH ITS SUBSTRATE, ANTIVIRAL DRUGS AND OTHER NUCLEOSIDE ANALOGUES  PROTEINS v.32;350,1998AINHIBITORY Mg ION BINDING RESIDUE D - 55
1nks_A_21nks   RefC.VONRHEIN,H.BOENISCH,G.SCHAEFER,G.E.SCHULZ. THE STRUCTURE OF A TRIMERIC ARCHAEAL ADENYLATE KINASE  J.MOL.BIOL. v.282;167,1998AP-ATP BINDING RESIDUES - 15
1nks_A_21nks   RefC.VONRHEIN,H.BOENISCH,G.SCHAEFER,G.E.SCHULZ. THE STRUCTURE OF A TRIMERIC ARCHAEAL ADENYLATE KINASE  J.MOL.BIOL. v.282;167,1998AP-ATP BINDING RESIDUET - 16
1qhi_A_481qhi   RefM.S.BENNETT,F.WIEN,J.N.CHAMPNESS,T.BATUWANGALA,T.RUTHERFORD,W.C.SUMMERS,H.SUN,G.WRIGHT,M.R.SANDERSON. STRUCTURE TO 1.9A RESOLUTION OF A COMPLEX WITH HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE OF A NOVEL NON-SUBSTRATE INHIBITOR: X-RAY CRYSTALLOGRAPHIC COMPARISON WITH BINDING OF ACICLOVIR  FEBS LETT. v.443;121,1999AINHIBITORY Mg ION BINDING RESIDUE D - 55
1shk_A_51shk   RefT.KRELL,J.E.COYLE,M.J.HORSBURGH,J.R.COGGINS,A.J.LAPTHORN. CRYSTALLIZATION AND PRELIMINARY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI  ACTA CRYSTALLOGR.,SECT.D v.53;612,1997AATP BINDING RESIDUEC - 13
1shk_A_51shk   RefT.KRELL,J.E.COYLE,M.J.HORSBURGH,J.R.COGGINS,A.J.LAPTHORN. CRYSTALLIZATION AND PRELIMINARY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI  ACTA CRYSTALLOGR.,SECT.D v.53;612,1997AMg ION BINDING RESIDUET - 16
2ki5_A_482ki5   RefM.S.BENNETT,F.WIEN,J.N.CHAMPNESS,T.BATUWANGALA,T.RUTHERFORD,W.C.SUMMERS,H.SUN,G.WRIGHT,M.R.SANDERSON. STRUCTURE TO 1.9A RESOLUTION OF A COMPLEX WITH HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE OF A NOVEL NON-SUBSTRATE INHIBITOR: X-RAY CRYSTALLOGRAPHIC COMPARISON WITH BINDING OF ACICLOVIR  FEBS LETT. v.443;121,1999AINHIBITORY Mg ION BINDING RESIDUE D - 55
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPG - 45
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPL - 46
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPP - 47
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPA - 48
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPA - 48
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPR - 49
3bif_A_393bif   RefM.H.YUEN,X.WANG,H.MIZUGUCHI,K.UYEDA,C.A.HASEMANN. A SWITCH IN THE KINASE DOMAIN OF RAT TESTIS 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE- 2,6-BISPHOSPHATASE  BIOCHEMISTRY v.38;12333,1999AP-LOOPG - 50
3tmk_A_73tmk   RefA.LAVIE,M.KONRAD,R.BRUNDIERS,R.S.GOODY,I.SCHLICHTING,J.REINSTEIN. CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR P1-(5'-ADENOSYL) P5-(5'-THYMIDYL) PENTAPHOSPHATE (TP5A) AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION  BIOCHEMISTRY v.37;3677,1998ACATALYTIC RESIDUER - 15
3tmk_A_73tmk   RefA.LAVIE,M.KONRAD,R.BRUNDIERS,R.S.GOODY,I.SCHLICHTING,J.REINSTEIN. CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR P1-(5'-ADENOSYL) P5-(5'-THYMIDYL) PENTAPHOSPHATE (TP5A) AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION  BIOCHEMISTRY v.37;3677,1998AMg ION BINDING RESIDUET - 16
3tmk_A_73tmk   RefA.LAVIE,M.KONRAD,R.BRUNDIERS,R.S.GOODY,I.SCHLICHTING,J.REINSTEIN. CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR P1-(5'-ADENOSYL) P5-(5'-THYMIDYL) PENTAPHOSPHATE (TP5A) AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION  BIOCHEMISTRY v.37;3677,1998AADENINE BINDING RESIDUEQ - 21

Clusters included in this Subclass
CLUSTER: EH.5.0
CLUSTER: EH.6.4