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Information on SUBCLASS 4.15.1
Subclass Accession number: 8457
Subclass: 4.15.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 23

Average sequence ID (%) : 16.2 +/- 16.0
Average RMSD (Å) : 0.670 +/- 0.269

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XXGXhpXh
(φψ)-conformation: aagababb
Pattern: xxxx[acilmvy]xx[DGN]x[acfilvy][adekrst]x[ailmvy]xx
Conservation:-0.534-1.090-0.590-0.5650.547-0.518-0.3773.259-0.317-0.1930.279-0.4150.3430.0200.151
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aa6_*_3861aa6   -386400LPHRAAHGEVRAAYIHHHHHHTTS--EEEEaaaaaaavababbbx
1aj6_*_341aj6   -4761AIDEALAGHCKEIIVHHHHHHTTS--EEEEaaaaaaavababbbb
1b93_A_701b93   A7488VGALISEGKIDVLIFHHHHHHTT---EEEEaaaaaaavababbbb
1cdo_A_3551cdo   A358372AIDLMKHGKCIRTVLHHHHHHTT--SEEEEaaaaaaalababbbx
1db3_A_1961db3   A203217AIANIAQGLESCLYLHHHHHHTTS---EEEaaaaaaavababbbb
1dc1_A_2861dc1   A292306IWDQLQSGSLTNSANHHHHHHHTSS-EEEEaaaaaaavababbbx
1dci_A_2331dci   A233246ADEALDSGLVSRVF.HHHHHHHTSSSEEE.aaaaaaavababbb.
1ddg_A_4991ddg   A502516WQRYVKEGVLTRIDLHHHHHHTTS--EEEEaaaaaaavaxabbbb
1dii_A_2581dii   A265279LRPLRMSNTIPNSVVHHHHHHTTSS-S-EEaaaaaaavabaxxxx
1ek6_A_2081ek6   A211225YVSQVAIGRREALNVHHHHHHHTSSS-EEEaaaaaaavababxbx
1fs0_G_1471fs0   G156170MLQAYDEGRLDKLYIHHHHHHTTS-S-EEEaaaaaaavababbbb
1gqn_A_941gqn   A101115NRAAIDSGLVDMIDLHHHHHHHS--SEEEEaaaaaaavababbxb
1gtk_A_1521gtk   A155169RLSKLDNGEYDAIILHHHHHHTTS-SEEEEaaaaaaavababbbb
1gtk_A_631gtk   A6680LEVALLENRADIAVHHHHHHHTTS-SEEEEaaaaaaavababbbb
1inp_*_2911inp   -294308KSLCVILGLADIYIFHHHHHHHTS-SEEEEaaaaaaavababbbb
1jp4_A_2211jp4   A224238KIIQLIEGKASAYVFHHHHHHTTS-SEEEEaaaaaaavababbbb
1ka1_A_2661ka1   A267281KYCLLALGLADVYLRHHHHHHHTS-SEEEEaaaaaaavababxbb
1o98_A_3761o98   A383397LLKEIEADKYDAIILHHHHHHTT--SEEEEaaaaaaalababbbb
1pix_A_5291pix   A529541PKVCAELGLVDEI..HHHHHHHTSSSEE..aaaaaaavababx..
1ptm_A_931ptm   A104118ACDGCLNGEFAALITHHHHHHHTS-SEEEEaaaaaaavababbbb
1tyf_A_1761tyf   A176188APEAVEYGLVDSI..HHHHHHHTS-SEE..aaaaaaagababx..
1udb_*_2001udb   -203217YIAQVAVGRRDSLAIHHHHHHHTSSS-EEEaaaaaaagababxxx
2nap_A_3972nap   A400414LFEALGRGDVKCMIIHHHHHHHTSS-EEEEaaaaaaavababbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aa6_*_3861aa6   *     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE M - 401
1aj6_*_341aj6   *     NOVNOVOBIOCIN V - 43
1aj6_*_341aj6   *     NOVNOVOBIOCIN D - 45
1aj6_*_341aj6   *     NOVNOVOBIOCIN N - 46
1aj6_*_341aj6   *     NOVNOVOBIOCIN A - 47
1aj6_*_341aj6   *     NOVNOVOBIOCIN D - 49
1aj6_*_341aj6   *     NOVNOVOBIOCIN E - 50
1b93_A_701b93   A     FMTFORMIC ACID D - 71
1b93_A_701b93   A     FMTFORMIC ACID F - 88
1cdo_A_3551cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 362
1cdo_A_3551cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 365
1cdo_A_3551cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE C - 367
1cdo_A_3551cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 368
1cdo_A_3551cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 369
1cdo_A_3551cdo   A     ZNZINC ION R - 369
1dci_A_2331dci   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED L - 237
1dci_A_2331dci   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED D - 238
1dci_A_2331dci   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED S - 239
1dci_A_2331dci   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED G - 240
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE L - 208
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE M - 209
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Y - 211
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE L - 223
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE N - 224
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE V - 225
1ek6_A_2081ek6   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE F - 226
1gtk_A_631gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID S - 81
1gtk_A_1521gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID V - 152
1gtk_A_1521gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID R - 155
1gtk_A_1521gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID I - 168
1gtk_A_1521gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID L - 169
1gtk_A_1521gtk   A     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID A - 170
1jp4_A_2211jp4   A     MGMAGNESIUM ION A - 221
1jp4_A_2211jp4   A     AMPADENOSINE MONOPHOSPHATE A - 221
1jp4_A_2211jp4   A     AMPADENOSINE MONOPHOSPHATE K - 224
1jp4_A_2211jp4   A     AMPADENOSINE MONOPHOSPHATE Y - 236
1jp4_A_2211jp4   A     AMPADENOSINE MONOPHOSPHATE F - 238
1ka1_A_2661ka1   A     A3PADENOSINE-3'-5'-DIPHOSPHATE K - 267
1ka1_A_2661ka1   A     A3PADENOSINE-3'-5'-DIPHOSPHATE Y - 279
1ka1_A_2661ka1   A     A3PADENOSINE-3'-5'-DIPHOSPHATE R - 281
1o98_A_3761o98   A     MNMANGANESE (II) ION N - 398
1ptm_A_931ptm   A     PO4PHOSPHATE ION T - 118
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE L - 200
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE M - 201
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE Y - 203
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE L - 215
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE A - 216
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE I - 217
1udb_*_2001udb   *     UFGURIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GALACTOSE F - 218
2nap_A_3972nap   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE I - 414
2nap_A_3972nap   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE C - 415
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gtk_A_1521gtk   A AC1DPM BINDING SITE FOR CHAIN AA - 170

Clusters included in this Subclass
CLUSTER: HE.3.94
CLUSTER: HE.4.116
CLUSTER: HE.4.119
CLUSTER: HE.5.28
CLUSTER: HE.6.62