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| Information on SUBCLASS 18.1.1 |
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Subclass Accession number: 9259
Subclass: 18.1.1 
Type: HH alpha-alpha DB: ArchDB-EC Image coordinates: 
 Consensus coordinates:
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Number of loops: 4 Average sequence ID (%) : 69.9 +/- 7.7 Average RMSD (Å) : 0.225 +/- 0.050 Consensus geometry
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| Consensus Sequence: | RHFGAEYXchppcYXcpGVDQL |
| (φψ)-conformation: | aapgpppabaappaplbeppaa |
| Pattern: | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
| Conservation: | 1.199 | 0.766 | 0.766 | 0.332 | 2.935 | 0.332 | 1.633 | 0.766 | 0.766 | -0.102 | 0.332 | 1.199 | -1.644 | -0.295 | -0.633 | -1.307 | -1.114 | -0.292 | 1.199 | -1.693 | -0.508 | -0.517 | 0.766 | -0.102 | 0.766 | 0.332 | -0.102 | -1.259 | -0.580 | -0.314 | -0.102 | -0.921 | -1.548 | -0.102 | -0.301 | -0.650 |
| Loops included in this Subclass |
| Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
| 1f28_A_113 | 1f28 | A | 113 | 148 | YGFQWRHFGAEYIDCKTNYIGQGVDQLANIIQKIRT | HHHHHHHBT-----TTS--TT-SB-HHHHHHHHHHH | aaaaaaapvxxxabaaxxapvxexxaaaaaaaaaaa |
| 1hvy_A_135 | 1hvy | A | 135 | 170 | YGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKT | HHHHHHHBTS----TT---TT-SB-HHHHHHHHHHH | aaaaaaapgxxxabaapxapvbexxaaaaaaaaaaa |
| 1hw3_A_135 | 1hw3 | A | 135 | 170 | YGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKT | HHHHHHSBT-----TTS--TT-SB-HHHHHHHHHHH | aaaaaaapvxxxabaapxapvxexxaaaaaaaaaaa |
| 1j3k_C_430 | 1j3k | C | 430 | 465 | YGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKN | HHHHHHHBTS----TTS--TT-SB-HHHHHHHHHHH | aaaaaaapvxxxabaaxxapvbexxaaaaaaaaaaa |
| PDB ligands within a cut-off distance of 6 Å in this subclass |
| Loop | PDB | Chain | Ligands | Residue |
| 1f28_A_113 | 1f28 | A | UMP2'-DEOXYURIDINE 5'-MONOPHOSPHATE | Y - 113 |
| 1f28_A_113 | 1f28 | A | F89S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN -9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID | Y - 113 |
| 1hvy_A_135 | 1hvy | A | UMP2'-DEOXYURIDINE 5'-MONOPHOSPHATE | Y - 135 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | Y - 135 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | Q - 138 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | W - 139 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | F - 142 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | Q - 160 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | R - 163 |
| 1hw3_A_135 | 1hw3 | A | CMES,S-(2-HYDROXYETHYL)THIOCYSTEINE | V - 164 |
| 1j3k_C_430 | 1j3k | C | UMP2'-DEOXYURIDINE 5'-MONOPHOSPHATE | Y - 430 |
| Clusters included in this Subclass |
| CLUSTER: HH.18.1 |
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