PDB: 1fmk Compound: tyrosine-protein kinase src Classification: PHOSPHOTRANSFERASE Entry date in PDB: 1997-08-20 Resolution [Å]: 1.50 R-Factor: 0.210

CHAIN: - SWISS-PROT/TREMBL: P12931    KEYWORD: 3D-structure    ATP-binding    Lipoprotein    Myristate    Phosphorylation    Proto-oncogene    SH2 domain    SH3 domain    Transferase    Tyrosine-protein kinase    EC: 2.7.1.112 SCOP: b.34.2.1 All beta proteins    SH3-like barrel    SH3-domain    SH3-domain    c-src protein tyrosine kinase    Human (Homo sapiens) SCOP: d.93.1.1 Alpha and beta proteins (a+b)    SH2-like    SH2 domain    SH2 domain    c-src tyrosine kinase    Human (Homo sapiens) SCOP: d.144.1.7 Alpha and beta proteins (a+b)    Protein kinase-like (PK-like)    Protein kinase-like (PK-like)    Protein kinases, catalytic subunit    c-src tyrosine kinase    Human (Homo sapiens) GO:  ATP binding    protein kinase activity    protein-tyrosine kinase activity    intracellular signaling cascade    protein amino acid phosphorylation

Image Source: PDB

Loops in ArchDB40 clusters

1fmk_*_267 - HA => SUBCLASS : 2.2.1
1fmk_*_196 - HA => SUBCLASS : 3.1.1
1fmk_*_184 - HA => SUBCLASS : 3.2.6
1fmk_*_280 - HA => SUBCLASS : 3.12.2
1fmk_*_118 - HA => SUBCLASS : 4.1.2
1fmk_*_212 - HA => SUBCLASS : 4.3.1
1fmk_*_392 - HA => SUBCLASS : 4.5.1
1fmk_*_325 - HA => SUBCLASS : 5.24.1
1fmk_*_171 - HA => SUBCLASS : 6.5.1
1fmk_*_84 - HA => SUBCLASS : 18.1.1
1fmk_*_219 - EH => SUBCLASS : 2.1.1
1fmk_*_335 - EH => SUBCLASS : 7.8.1
1fmk_*_352 - HH => SUBCLASS : 2.1.9
1fmk_*_431 - HH => SUBCLASS : 4.7.1
1fmk_*_468 - HH => SUBCLASS : 11.1.1

Loops in ArchDB95 clusters

1fmk_*_219 - EH => SUBCLASS : 2.1.1
1fmk_*_149 - EH => SUBCLASS : 4.40.1
1fmk_*_290 - EH => SUBCLASS : 6.58.1
1fmk_*_335 - EH => SUBCLASS : 7.13.1
1fmk_*_352 - HH => SUBCLASS : 2.1.7
1fmk_*_431 - HH => SUBCLASS : 4.3.1
1fmk_*_489 - HH => SUBCLASS : 9.1.4
1fmk_*_441 - HH => SUBCLASS : 10.1.1
1fmk_*_468 - HH => SUBCLASS : 11.1.1
1fmk_*_267 - HA => SUBCLASS : 2.2.1
1fmk_*_196 - HA => SUBCLASS : 3.1.1
1fmk_*_392 - HA => SUBCLASS : 3.2.1
1fmk_*_184 - HA => SUBCLASS : 3.3.8
1fmk_*_118 - HA => SUBCLASS : 4.1.2
1fmk_*_212 - HA => SUBCLASS : 4.2.1
1fmk_*_325 - HA => SUBCLASS : 5.16.1
1fmk_*_171 - HA => SUBCLASS : 7.1.1

Loops in ArchDB-EC clusters

1fmk_*_468 - HH => SUBCLASS : 11.1.1

Loops not clustered in ArchDB

1fmk_*_129 - AR
1fmk_*_137 - AR
1fmk_*_243 - AR
1fmk_*_137 - AR
1fmk_*_129 - AR
1fmk_*_243 - AR
1fmk_*_400 - EH
1fmk_*_212 - HA
1fmk_*_196 - HA
1fmk_*_267 - HA
1fmk_*_280 - HA
1fmk_*_184 - HA
1fmk_*_171 - HA
1fmk_*_325 - HA
1fmk_*_118 - HA
1fmk_*_392 - HA
1fmk_*_107 - HA
1fmk_*_84 - HA
1fmk_*_107 - HA
1fmk_*_304 - HE
1fmk_*_223 - HE
1fmk_*_155 - HE
1fmk_*_360 - HE
1fmk_*_346 - HH

1a07 A - percentage of sequence identity: 100
1a07 B - percentage of sequence identity: 100
1a08 A - percentage of sequence identity: 100
1a08 B - percentage of sequence identity: 100
1a09 A - percentage of sequence identity: 100
1a09 B - percentage of sequence identity: 100
1a0n B - percentage of sequence identity: 78
1a1a A - percentage of sequence identity: 99
1a1a B - percentage of sequence identity: 99
1a1b A - percentage of sequence identity: 100
1a1b B - percentage of sequence identity: 100
1a1c A - percentage of sequence identity: 100
1a1c B - percentage of sequence identity: 100
1a1e A - percentage of sequence identity: 100
1a1e B - percentage of sequence identity: 100
1ad5 A - percentage of sequence identity: 61
1ad5 B - percentage of sequence identity: 61
1aot F - percentage of sequence identity: 66
1aou F - percentage of sequence identity: 66
1avz C - percentage of sequence identity: 76
1azg B - percentage of sequence identity: 78
1bkl - - percentage of sequence identity: 96
1bkm - - percentage of sequence identity: 96
1efn C - percentage of sequence identity: 75
1f1w A - percentage of sequence identity: 96
1fyn A - percentage of sequence identity: 76
1g83 A - percentage of sequence identity: 71
1g83 B - percentage of sequence identity: 71
1hcs B - percentage of sequence identity: 100
1hct B - percentage of sequence identity: 100
1is0 A - percentage of sequence identity: 97
1is0 B - percentage of sequence identity: 97
1kc2 A - percentage of sequence identity: 94
1ksw A - percentage of sequence identity: 99
1m27 C - percentage of sequence identity: 77
1nlo C - percentage of sequence identity: 98
1nlp C - percentage of sequence identity: 98
1nyf - - percentage of sequence identity: 78
1nyg - - percentage of sequence identity: 78
1nzl A - percentage of sequence identity: 97
1nzl B - percentage of sequence identity: 97
1nzv A - percentage of sequence identity: 97
1nzv B - percentage of sequence identity: 97
1o41 A - percentage of sequence identity: 100
1o42 A - percentage of sequence identity: 100
1o43 A - percentage of sequence identity: 100
1o44 A - percentage of sequence identity: 100
1o45 A - percentage of sequence identity: 100
1o46 A - percentage of sequence identity: 100
1o47 A - percentage of sequence identity: 100
1o48 A - percentage of sequence identity: 100
1o49 A - percentage of sequence identity: 100
1o4a A - percentage of sequence identity: 100
1o4b A - percentage of sequence identity: 100
1o4c A - percentage of sequence identity: 100
1o4d A - percentage of sequence identity: 100
1o4e A - percentage of sequence identity: 100
1o4f A - percentage of sequence identity: 100
1o4g A - percentage of sequence identity: 100
1o4h A - percentage of sequence identity: 100
1o4i A - percentage of sequence identity: 100
1o4j A - percentage of sequence identity: 100
1o4k A - percentage of sequence identity: 100
1o4l A - percentage of sequence identity: 100
1o4m A - percentage of sequence identity: 100
1o4n A - percentage of sequence identity: 100
1o4o A - percentage of sequence identity: 100
1o4p A - percentage of sequence identity: 100
1o4q A - percentage of sequence identity: 100
1o4r A - percentage of sequence identity: 100
1p13 A - percentage of sequence identity: 97
1p13 B - percentage of sequence identity: 97
1prl C - percentage of sequence identity: 98
1prm C - percentage of sequence identity: 98
1qpd A - percentage of sequence identity: 67
1qpe A - percentage of sequence identity: 67
1qpj A - percentage of sequence identity: 67
1qwe A - percentage of sequence identity: 98
1qwf A - percentage of sequence identity: 98
1rlp C - percentage of sequence identity: 98
1rlq C - percentage of sequence identity: 98
1sha A - percentage of sequence identity: 97
1shb A - percentage of sequence identity: 97
1shd A - percentage of sequence identity: 100
1shf B - percentage of sequence identity: 76
1skj - - percentage of sequence identity: 97
1spr A - percentage of sequence identity: 97
1spr B - percentage of sequence identity: 97
1spr C - percentage of sequence identity: 97
1spr D - percentage of sequence identity: 97
1sps A - percentage of sequence identity: 97
1sps B - percentage of sequence identity: 97
1sps C - percentage of sequence identity: 97
1srl - - percentage of sequence identity: 98
1srm - - percentage of sequence identity: 98
1y57 A - percentage of sequence identity: 100
1yoj A - percentage of sequence identity: 98
1yoj B - percentage of sequence identity: 98
1yol A - percentage of sequence identity: 99
1yol B - percentage of sequence identity: 99
1yom A - percentage of sequence identity: 98
1yom B - percentage of sequence identity: 98
1zbj A - percentage of sequence identity: 76
2hck A - percentage of sequence identity: 61
2hck B - percentage of sequence identity: 61
2ptk - - percentage of sequence identity: 98
2src - - percentage of sequence identity: 100
3lck - - percentage of sequence identity: 67