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Information on SUBCLASS 3.4.1
Subclass Accession number: 1157
Subclass: 3.4.1 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 42

Average sequence ID (%) : 9.7 +/- 12.0
Average RMSD (Å) : 0.564 +/- 0.230

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: hXXXpXX
(φψ)-conformation: bblppaa
Pattern: x[acfgilmvy]x[afgiklmtv]x[aegknrs]x[adegknrst]xxx[afgiklmtv]x[adeknqrst]
Conservation:-0.5350.419-0.872-0.012-1.0272.291-1.2580.904-1.302-0.2960.4290.237-0.0031.026
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1c0a_A_2281c0a   A233246DVETSFMTAPQVREEEEEES--HHHHHHxbbbblbxaaaaaa
1ccw_A_1151ccw   A115128RVYAPGTPPEVGIAEE--TT--HHHHHHbbbxpvxxaaaaaa
1e79_A_2001e79   A202215IYVAIGQKRSTVAQEEEEES--HHHHHHbbbxbvxxaaaaaa
1f08_A_1891f08   A193206VLAVFGLAEVFFEAEEEEES--HHHHHHbbbbbvxxaaaaaa
1f1s_A_8911f1s   A893906YMMVPNIDRTSFDKEEEEES--HHHHHHbbbbxlbxaaaaaa
1g12_A_21g12   A212...YNGCSSSEQSA...EES--HHHHHH...xbvbxaaaaaa
1gve_A_1331gve   A135148ELGLSNYVSWEVAEEEEEES--HHHHHHbxbbbvxxaaaaaa
1hsk_A_2751hsk   A275288MVNVDNGTATDYENEEE-SS--HHHHHHbxxablxbaaaaaa
1hx0_A_121hx0   A1326IVHLFEWRWVDIALEEEETT--HHHHHHbbxxxvxxaaaaaa
1iae_*_141iae   -1629PYTFAGVSGADQSAEEEEES--HHHHHHwbbbbvbxaaaaaa
1j0m_A_6381j0m   A642655YVLLPNKTSAQVGAEEEEET--HHHHHHbbxbxlbxaaaaaa
1jo0_A_471jo0   A4962KVKVAGADRETKQLEEEETT--HHHHHHbbxbxvbxaaaaaa
1k8k_A_1101k8k   A112125LTEPPLNTPENREYEEE-TT--HHHHHHbbbwxvxxaaaaaa
1kng_A_1121kng   A114127VGINYKDAADNARREEEEES--HHHHHHbbbxblbxaaaaaa
1l0l_B_2041l0l   B205218ALIGLGVSHPVLKQEEEEESS-HHHHHHbbbbbvbxaaaaaa
1l0w_A_2341l0w   A239252DLEMSFVEVEDVLEEEEEES--HHHHHHbbbbblbbaaaaaa
1lu4_A_10571lu4   A10591072VGIATRADVGAMQSEEEE-SS-HHHHHHbxbbbvbxaaaaaa
1m55_A_881m55   A93106LVETSGISSMVLGREEE-TT--HHHHHHxbpapvbxaaaaaa
1mla_*_1301mla   -132145MAAIIGLDDASIAKEEEEES--HHHHHHbbxbbvbxaaaaaa
1mww_A_601mww   A6477INLMAGRMEGTKKREEEETT--HHHHHHbbbxxgxxaaaaaa
1n7o_A_7911n7o   A795808YMLIPNVDRATFNQEEEEES--HHHHHHbbxbxvbxaaaaaa
1nnh_A_1131nnh   A118131DFEVERAKMEDIMREEEEET--HHHHHHbbbbpvxbaaaaaa
1nsj_*_551nsj   -5770VGVFVNEEPEKILDEEEESS--HHHHHHbbxbblxxaaaaaa
1o4u_A_2041o4u   A204217IVMLDNLSPEEVKDEEEEES--HHHHHHbbbxxlbxaaaaaa
1otf_A_31otf   A619LYIIEGRTDEQKETEEEES---HHHHHHbbbxpgxxaaaaaa
1p42_A_2571p42   A257270KFYSFRGGHSLNVKEEEEES--HHHHHHbbbbbvxbaaaaaa
1pne_*_1081pne   -112125LMGKEGVHGGMINKEEE-TT--HHHHHHbbxxxvxpaaaaaa
1pyf_A_1521pyf   A152164.IGVSNFSLEQLKE.EEEES--HHHHHH.bbbbvxxaaaaaa
1q15_A_51q15   A518FCVVYKGSDTDINNEEEEET--HHHHHHbbbbxlxbaaaaaa
1qpo_A_2181qpo   A218231LILLDNFAVWQTQTEEEEET--HHHHHHbbxxxlxxaaaaaa
1qz5_A_1031qz5   A105118LTEAPLNPKANREKEEE-TT--HHHHHHbbbxplxwaaaaaa
1rhc_A_1891rhc   A189202HLMTVAAAPSTLKNEEEEES--HHHHHHbxbbblbxaaaaaa
1rlh_A_741rlh   A7689VILIRNAYPINILNEEEEES--HHHHHHbbbbbvbxaaaaaa
1rwh_A_6221rwh   A626639YMVAPGASVDLTRKEEEEET--HHHHHHbbbbxvxxaaaaaa
1s0y_A_31s0y   A619CDMRYGRTDEQKRAEEEETT--HHHHHHbxbxxgxxaaaaaa
1s0y_B_31s0y   B619CHIATGLSVARKQQEEEETT--HHHHHHbbbxxgxxaaaaaa
1st9_A_951st9   A98111VAVNVGESKIAVHNEEEEES--HHHHHHbxxxxvxxaaaaaa
1su4_A_6751su4   A675686..CFARVEPSHKSK..EEES--HHHHHH..bbblbxaaaaaa
1t15_A_16511t15   A16511664SMVVSGLTPEEFMLEEEEES--HHHHHHbbbbbvxxaaaaaa
1us0_A_1561us0   A156168.IGISNFNHLQVEM.EEEES--HHHHHH.bbbbvxxaaaaaa
1uxy_*_2911uxy   -292305LINEDNAKSEDVVQEEE-SS--HHHHHHxbxablxxaaaaaa
1zpd_A_3171zpd   A317329.IRFPSVHLKDYLT.EEEES--HHHHHH.bbbxvbxaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE E - 228
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE F - 229
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE T - 230
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE Q - 231
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE D - 233
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE V - 234
1c0a_A_2281c0a   A     AMOASPARTYL-ADENOSINE-5'-MONOPHOSPHATE E - 235
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN Y - 117
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN A - 118
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 119
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN G - 120
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN T - 121
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 122
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN P - 123
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN V - 125
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN G - 126
1ccw_A_1151ccw   A     CNCCO-CYANOCOBALAMIN I - 127
1e79_A_2001e79   A     MGMAGNESIUM ION Y - 203
1e79_A_2001e79   A     MGMAGNESIUM ION Q - 208
1gve_A_1331gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 139
1gve_A_1331gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 140
1gve_A_1331gve   A     CITCITRIC ACID N - 140
1gve_A_1331gve   A     GOLGLYCEROL V - 142
1gve_A_1331gve   A     GOLGLYCEROL W - 144
1gve_A_1331gve   A     GOLGLYCEROL E - 145
1gve_A_1331gve   A     GOLGLYCEROL E - 148
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL R - 20
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL W - 21
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL V - 22
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL E - 27
1hx0_A_121hx0   A     EGLETHYLENE GLYCOL R - 30
1j0m_A_6381j0m   A     CACALCIUM ION Y - 656
1jo0_A_471jo0   A     GOLGLYCEROL L - 47
1jo0_A_471jo0   A     GOLGLYCEROL K - 49
1jo0_A_471jo0   A     GOLGLYCEROL K - 51
1jo0_A_471jo0   A     GOLGLYCEROL Q - 61
1jo0_A_471jo0   A     GOLGLYCEROL I - 64
1jo0_A_471jo0   A     GOLGLYCEROL N - 65
1jo0_A_471jo0   A     GOLGLYCEROL A - 66
1jo0_A_471jo0   A     GOLGLYCEROL V - 68
1jo0_A_471jo0   A     GOLGLYCEROL R - 69
1m55_A_881m55   A     ZNZINC ION H - 89
1m55_A_881m55   A     ZNZINC ION H - 91
1m55_A_881m55   A     ZNZINC ION E - 95
1m55_A_881m55   A     ZNZINC ION S - 97
1p42_A_2571p42   A     ZNZINC ION H - 265
1p42_A_2571p42   A     MYRMYRISTIC ACID H - 265
1qz5_A_1031qz5   A     HIC4-METHYL-HISTIDINE A - 108
1rhc_A_1891rhc   A     F42COENZYME F420 M - 191
1rhc_A_1891rhc   A     F42COENZYME F420 T - 192
1rhc_A_1891rhc   A     F42COENZYME F420 V - 193
1rhc_A_1891rhc   A     ACNACETONE V - 193
1s0y_B_31s0y   B     MLAMALONIC ACID F - 3
1s0y_A_31s0y   A     MLAMALONIC ACID D - 7
1s0y_A_31s0y   A     MLAMALONIC ACID M - 8
1s0y_A_31s0y   A     MLAMALONIC ACID R - 9
1s0y_A_31s0y   A     MLAMALONIC ACID R - 12
1t15_A_16511t15   A     SEPPHOSPHOSERINE V - 1654
1t15_A_16511t15   A     SEPPHOSPHOSERINE S - 1655
1t15_A_16511t15   A     SEPPHOSPHOSERINE G - 1656
1t15_A_16511t15   A     SEPPHOSPHOSERINE L - 1657
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 159
1us0_A_1561us0   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 160
1us0_A_1561us0   A     LDTIDD594 N - 160
1us0_A_1561us0   A     CITCITRIC ACID F - 161
1us0_A_1561us0   A     CITCITRIC ACID N - 162
1us0_A_1561us0   A     CITCITRIC ACID H - 163
1us0_A_1561us0   A     CITCITRIC ACID L - 164
1uxy_*_2911uxy   *     EPUURIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID V - 291
1zpd_A_3171zpd   A     CITCITRIC ACID R - 318
1zpd_A_3171zpd   A     CITCITRIC ACID F - 319
1zpd_A_3171zpd   A     CITCITRIC ACID P - 320
1zpd_A_3171zpd   A     CITCITRIC ACID S - 321
1zpd_A_3171zpd   A     CITCITRIC ACID V - 322
1zpd_A_3171zpd   A     CITCITRIC ACID H - 323
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gve_A_1331gve   A AC1NAP BINDING SITE FOR CHAIN AS - 139
1gve_A_1331gve   A AC1NAP BINDING SITE FOR CHAIN AN - 140
1gve_A_1331gve   A AC7GOL BINDING SITE FOR CHAIN AE - 145
1gve_A_1331gve   A AC7GOL BINDING SITE FOR CHAIN AE - 148
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AN - 162
1us0_A_1561us0   A CT1CIT BINDING SITE FOR CHAIN AH - 163

Clusters included in this Subclass
CLUSTER: EH.2.22
CLUSTER: EH.3.13
CLUSTER: EH.4.6
CLUSTER: EH.5.231
CLUSTER: EH.6.59