ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.7.1

Subclass Accession number: 1811
Subclass: 4.7.1

Type: AR beta-beta link
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0004175 (>75 %) GO:0004190 (>75 %) GO:0008233 (>75 %)
SCOP : 50629 (>50 %) 50630 (>50 %) 51268 (>75 %) 51283 (>75 %) 51284 (>75 %)

Number of loops: 22

Average sequence ID (%) : 12.3 +/- 17.2
Average RMSD (Å) : 0.741 +/- 0.275

Consensus geometry

d (Å): 9

delta (°): 90-135

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	hXXXpXXX
(φψ)-conformation:	bbaapabb

Pattern:	x	x	[acfilv]	[dhnpst]	x	[adegkrst]	[adeknqrst]	[deknpst]	[adgknqst]	[acfilmtv]	x
Conservation:	-0.232	0.094	0.514	1.512	-1.698	0.043	1.150	0.950	-0.571	-0.434	-1.328

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a3q_A_120	1a3q	A	122	132	VSVGPKDMTAQ	EEE-SS--EEE	bbxpaaxabbb
1bd2_D_44	1bd2	D	47	57	ISISSIKDKNA	EEEETT-SEEE	ebbxaaxabbb
1c39_A_113	1c39	A	117	127	ISCNRHTLADN	EEE-TT-SSEE	bxxbaababbv
1cfb_*_763	1cfb	-	766	776	NIFDWRQNNIV	EE--TT--EEE	xbaxaaxabbb
1cv8_*_148	1cv8	-	148	158	MTQDAKNNVIP	EEEETT--EEE	bbbxaababxx
1eje_A_123	1eje	A	123	131	..RIVEAPGHL	..EETT-SEEE	..bxaaxabbb
1ezv_A_246	1ezv	A	249	259	RLRDDTLPKAW	EEE-TTSSSEE	bapbaaxabbb
1fkn_A_25	1fkn	A	29	39	ILVDTGSSNFA	EEEETT---EE	bxxbaababxb
1fna_*_46	1fna	-	48	58	FTVPGSKSTAT	EEEETT--EEE	bbbpaababbx
1fnf_*_1190	1fnf	-	1192	1202	EVVHADQSSCT	EEE-TT--EEE	bbbxaaxabbb
1fnf_*_1281	1fnf	-	1283	1293	LSISPSDNAVV	EEE-TT--EEE	bbbpaababbb
1fnf_*_1371	1fnf	-	1373	1383	DRVPHSRNSIT	EEEETT--EEE	bbbxaaxabbb
1hrn_A_25	1hrn	A	29	39	VVFDTGSSNVW	EEEETT---EE	bxxbaababbb
1htr_B_25	1htr	B	29	39	VLFDTGSSNLW	EEEETT---EE	bxxbaababbb
1j71_A_207	1j71	A	215	225	VVLDSGTTITY	EEE-TT-SSEE	bxxxaababbb
1lf2_A_204	1lf2	A	211	221	CIVDSGTSAIT	EEE-TT--SEE	bxxbaababxb
1lf2_A_27	1lf2	A	31	41	FILDTGSANLW	EEEETT---EE	bxxbaababbb
1oew_A_28	1oew	A	32	42	LDFDTGSSDLW	EEEETT---EE	bxxbaababbb
1pl3_A_44	1pl3	A	48	58	VVAPIASKWIG	EEEETT--EEE	bbbpaaxabbb
1qpx_A_8	1qpx	A	9	19	AVFDGSEKSMT	EEEETTSSEEE	bbxxaababbb
1svb_*_161	1svb	-	163	173	ASFTISSEKTI	EEEBTTB-EEE	bbbbaababbb
1ten_*_847	1ten	-	849	859	IDLTEDENQYS	EEEETT--EEE	bbxxaaxabbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1c39_A_113	1c39	A	P3M1-3 SUGAR RING OF PENTAMANNOSYL 6-PHOSPHATE	E - 133
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	V - 30
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	D - 32
1hrn_A_25	1hrn	A	IP31-HYDROXY-3-METHYLBUTANE	D - 32
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	T - 33
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	G - 34
1hrn_A_25	1hrn	A	IP31-HYDROXY-3-METHYLBUTANE	G - 34
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	S - 35
1hrn_A_25	1hrn	A	IP31-HYDROXY-3-METHYLBUTANE	S - 35
1hrn_A_25	1hrn	A	CHA1-HYDROXY-2-AMINO-3-CYCLOHEXYLPROPANE	W - 39
1j71_A_207	1j71	A	EOHETHANOL	D - 218
1j71_A_207	1j71	A	EOHETHANOL	T - 221
1j71_A_207	1j71	A	EOHETHANOL	Y - 225
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	I - 32
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	D - 34
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	T - 35
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	G - 36
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	S - 37
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	A - 38
1lf2_A_27	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	N - 39
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	I - 212
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	D - 214
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	S - 215
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	G - 216
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	T - 217
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	S - 218
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	A - 219
1lf2_A_204	1lf2	A	R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE	T - 221
1oew_A_28	1oew	A	SERSERINE	D - 35
1oew_A_28	1oew	A	THRTHREONINE	D - 35
1oew_A_28	1oew	A	SERSERINE	G - 37
1oew_A_28	1oew	A	THRTHREONINE	G - 37
1oew_A_28	1oew	A	SERSERINE	S - 38
1oew_A_28	1oew	A	THRTHREONINE	S - 38
1oew_A_28	1oew	A	THRTHREONINE	S - 39
1oew_A_28	1oew	A	THRTHREONINE	D - 40
1pl3_A_44	1pl3	A	NAGN-ACETYL-D-GLUCOSAMINE	V - 49
1pl3_A_44	1pl3	A	HEMPROTOPORPHYRIN IX CONTAINING FE	W - 56
1pl3_A_44	1pl3	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 57
1pl3_A_44	1pl3	A	HEMPROTOPORPHYRIN IX CONTAINING FE	G - 58
1pl3_A_44	1pl3	A	HEMPROTOPORPHYRIN IX CONTAINING FE	I - 59
1pl3_A_44	1pl3	A	HEMPROTOPORPHYRIN IX CONTAINING FE	A - 60

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1oew_A_28	1oew	A	CATCATALYTIC SITE	D - 35
1oew_A_28	1oew	A	AC1SER BINDING SITE FOR CHAIN A	G - 37

Clusters included in this Subclass