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Information on SUBCLASS 6.1.2
Subclass Accession number: 5852
Subclass: 6.1.2 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 29

Average sequence ID (%) : 16.3 +/- 17.7
Average RMSD (Å) : 0.766 +/- 0.335

Consensus geometry
d (Å): 13 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XXcXXhpphX
(φψ)-conformation: aalbpaaabb
Pattern: x[acilmpvw]x[degknqrst]xx[dgknqrs][aiklm][dknprst]x[dehknqst][dehknqrsy][hilvy]x[fgiklv]x
Conservation:-0.4760.809-0.3730.528-1.237-0.7171.862-0.6070.561-0.9211.0060.6311.172-1.3670.466-1.337
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bjp_A_131bjp   A2641AISRSLDAPLTSVRVIHHHHHHT--GGG-EEEaaaaaavbxaaaxbbb
1bt0_A_231bt0   A2944RVEEKEGIPPVQQRLIHHHHHH---GGGEEEEaaaaaavxxaaaxbbb
1dbx_A_321dbx   A3247EAAEKLGIDPNRSFKTHHHHHHT--GGGBEEEaaaaaavbpaaaxbbb
1dp4_A_2161dp4   A224239LLALNAGLTGEDYVFFHHHHHTT--TTT-EEEaaaaaavxbaaabbbx
1dpt_A_181dpt   A2540AAASILGKPADRVNVTHHHHHH-S-GGG-EEEaaaaaavbwaaabbbb
1gd0_A_181gd0   A2540QLAQATGKPPQYIAVHHHHHHH---GGG-EEEaaaaaavxxaaaxbbb
1gd0_A_691gd0   A8297LLAERLRISPDRVYINHHHHHH---GGGEEEEaaaaaavbxaaabbbx
1gyx_A_141gyx   A2742VIIRHLNSKDSSISIAHHHHHHT--GGG-EEEaaaaaalbbaaabbbb
1hfo_A_181hfo   A2540LVGNILSKPGSYVAVHHHHHHHT--GGG-EEEaaaaaavbxaaaxbbb
1j5w_A_881j5w   A94109ESLEYLGINLKEHDIRHHHHHTT--TTTS-EEaaaaaavbxaaabxbb
1lc5_A_131lc5   A1428EPATVLGISPDQLLD.HHHHHHTS-GGGSEE.aaaaaavbxaaaxbx.
1lm8_B_241lm8   B3045IVEGILKRPPDEQRLYHHHHHH---GGGEEEEaaaaaalbwaaabbbb
1mfi_A_181mfi   A2540QLAQATGKPAQYIAVHHHHHHH---GGG-EEEaaaaaavxwaaabbbb
1mfi_A_691mfi   A8297LLSDRLHISPDRVYINHHHHHH---GGGEEEEaaaaaavxxaaabbbx
1mww_A_721mww   A85100ELEYKLGIRAHDVEITHHHHHH---GGGEEEEaaaaaavxpaaabbbb
1ndd_A_231ndd   A2944RVEEKEGIPPQQQRLIHHHHHH---GGGEEEEaaaaaavxxaaaxbbb
1o0s_A_2941o0s   A309324TCTRVTKKLVSQEKYLHHHHHH---GGG--EEaaaaaaUbxaaabbbb
1ofu_X_891ofu   X90105EWLRRAGLNRERILLLHHHHHTT--TTSEEEEaaaaaavxxaaabbbb
1ogw_A_231ogw   A2943KIQDKEGIPPDQQRL.HHHHHH---GGGEEE.aaaaaavxpaaaxbb.
1otf_A_141otf   A2742AMANSLDAPLERVRVLHHHHHHT--GGG-EEEaaaaaalbpaaaxbbb
1qlv_A_961qlv   A117132KAIDEWGLPKSKITHLHHHHHH-S-GGG--EEaaaaaavxxaaaxabb
1qus_A_1891qus   A201215LMARDEQDDPLNLKG.HHHHHTT--GGG-EE.aaaaaalbxaaaxbb.
1s0y_A_141s0y   A2742VISEATGEPRENIFFVHHHHHH---GGG-EEEaaaaaavxxaaabbbb
1s0y_B_141s0y   B2742VTNKSIGSDPKIINVLHHHHHH---GGG-EEEaaaaaavxxaaabbbb
1st0_A_2381st0   A251266AILQRYRMKGDHLRVYHHHHHH---GGGEEEEaaaaaavxxaaabbbb
1ui0_A_571ui0   A6479RILEAAGIPREEVYITHHHHHHT--GGGSEEEaaaaaavbxaaabbbb
1vk2_A_671vk2   A6984ELLRESGIRREDVYICHHHHHTT--GGGSEEEaaaaaavbxaaabbbb
2gac_B_2282gac   B241256KIVNRRGKNLKDIQVGHHHHHTT--GGG--EEaaaaaalbxaaabbbb
2pth_*_712pth   -7691AMASFFRINPDEILVAHHHHHHT--GGGEEEEaaaaaalbxaaabbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bjp_A_131bjp   A     OXP2-OXO-3-PENTENOIC ACID S - 37
1bjp_A_131bjp   A     OXP2-OXO-3-PENTENOIC ACID V - 38
1bjp_A_131bjp   A     OXP2-OXO-3-PENTENOIC ACID R - 39
1bjp_A_131bjp   A     OXP2-OXO-3-PENTENOIC ACID M - 45
1bt0_A_231bt0   A     EDO1,2-ETHANEDIOL E - 31
1bt0_A_231bt0   A     EDO1,2-ETHANEDIOL K - 33
1bt0_A_231bt0   A     EDO1,2-ETHANEDIOL E - 34
1bt0_A_231bt0   A     EDO1,2-ETHANEDIOL P - 37
1bt0_A_231bt0   A     EDO1,2-ETHANEDIOL P - 38
1dbx_A_321dbx   A     MSESELENOMETHIONINE K - 46
1dbx_A_321dbx   A     MSESELENOMETHIONINE L - 48
1dbx_A_321dbx   A     MSESELENOMETHIONINE L - 49
1dbx_A_321dbx   A     MSESELENOMETHIONINE V - 50
1dbx_A_321dbx   A     MSESELENOMETHIONINE A - 51
1gd0_A_181gd0   A     CITCITRIC ACID H - 40
1gd0_A_181gd0   A     CITCITRIC ACID V - 42
1gd0_A_691gd0   A     CITCITRIC ACID N - 97
1gd0_A_691gd0   A     CITCITRIC ACID Y - 99
1gyx_A_141gyx   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID S - 34
1gyx_A_141gyx   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID S - 38
1j5w_A_881j5w   A     MSESELENOMETHIONINE Y - 98
1j5w_A_881j5w   A     MSESELENOMETHIONINE L - 99
1mfi_A_181mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE K - 32
1mfi_A_181mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE Y - 36
1mfi_A_181mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE I - 37
1mfi_A_691mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE Y - 95
1mfi_A_691mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE I - 96
1mfi_A_691mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE N - 97
1mfi_A_691mfi   A     FHC2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE Y - 99
1mww_A_721mww   A     GLUGLUTAMIC ACID E - 98
1o0s_A_2941o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE D - 294
1o0s_A_2941o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE D - 295
1o0s_A_2941o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE I - 296
1o0s_A_2941o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE T - 299
1o0s_A_2941o0s   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE F - 326
1ogw_A_231ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE I - 23
1ogw_A_231ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE V - 26
1ogw_A_231ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE K - 27
1ogw_A_231ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE I - 30
1ogw_A_231ogw   A     LEF(4S)-5-FLUORO-L-LEUCINE L - 43
1qus_A_1891qus   A     BCNBICINE Y - 191
1qus_A_1891qus   A     EDO1,2-ETHANEDIOL Y - 191
1qus_A_1891qus   A     EDO1,2-ETHANEDIOL F - 192
1s0y_B_141s0y   B     MLAMALONIC ACID S - 34
1s0y_B_141s0y   B     MLAMALONIC ACID I - 38
1s0y_B_141s0y   B     MLAMALONIC ACID I - 39
1s0y_A_141s0y   A     MLAMALONIC ACID F - 40
1s0y_B_141s0y   B     MLAMALONIC ACID N - 40
1st0_A_2381st0   A     GTG7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE L - 267
1st0_A_2381st0   A     GTG7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE H - 268
1ui0_A_571ui0   A     URAURACIL A - 58
1ui0_A_571ui0   A     URAURACIL G - 59
1ui0_A_571ui0   A     URAURACIL L - 61
1ui0_A_571ui0   A     URAURACIL R - 64
1ui0_A_571ui0   A     URAURACIL I - 65
1ui0_A_571ui0   A     URAURACIL A - 68
1ui0_A_571ui0   A     URAURACIL I - 78
1ui0_A_571ui0   A     URAURACIL T - 79
1ui0_A_571ui0   A     URAURACIL N - 80
1vk2_A_671vk2   A     MSESELENOMETHIONINE L - 67
1vk2_A_671vk2   A     MSESELENOMETHIONINE T - 68
1vk2_A_671vk2   A     MSESELENOMETHIONINE E - 69
1vk2_A_671vk2   A     MSESELENOMETHIONINE L - 70
1vk2_A_671vk2   A     MSESELENOMETHIONINE R - 78
1vk2_A_671vk2   A     MSESELENOMETHIONINE Y - 82
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gyx_A_141gyx   A AC1EPE BINDING SITE FOR CHAIN BS - 38

Clusters included in this Subclass
CLUSTER: HE.6.17
CLUSTER: HE.7.2
CLUSTER: HE.8.2
CLUSTER: HE.8.92
CLUSTER: HE.9.38