ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.1.12

Subclass Accession number: 7028
Subclass: 1.1.12

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 26

Average sequence ID (%) : 10.5 +/- 14.2
Average RMSD (Å) : 0.469 +/- 0.176

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	XhpXp
(φψ)-conformation:	bbpaa

Pattern:	x	x	[acfgilvy]	[dehnqrsty]	x	[adegknrt]	[adegknqrs]	x	[deknpqrs]	[adegkqrs]	x
Conservation:	-0.053	-0.854	0.329	-0.150	-0.913	1.609	0.747	-1.335	1.526	0.111	-1.018

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b93_A_13	1b93	A	16	26	LVAHDHCKQML	EEE-GGGHHHH	bbbxaaaaaaa
1c30_A_944	1c30	A	947	957	LSVREGDKERV	EE--GGGHHHH	bbbxaaaaaaa
1dug_A_28	1dug	A	30	40	HLYERDEGDKW	EEE-TT-HHHH	bxxxaaaaaaa
1eke_A_20	1eke	A	23	33	FAIEKEREEEL	EEE-GGGHHHH	bbbxaaaaaaa
1evl_A_378	1evl	A	386	396	IFCTEEQIRDE	EEE-GGGHHHH	bxbxaaaaaaa
1ez0_A_404	1ez0	A	409	419	IHATEEDYPQV	EE--GGGHHHH	bbbbaaaaaaa
1fi4_A_307	1fi4	A	309	319	LYYLAENESKL	EEE-GGGHHHH	bxbxaaaaaaa
1gx5_A_450	1gx5	A	452	462	YSIEPLDLPQI	EEE-GGGHHHH	xbbxaaaaaaa
1gyx_A_40	1gyx	A	44	54	QQIQPESWQAI	EE--GGGHHHH	bxbxaaaaaaa
1h2k_A_214	1h2k	A	217	227	ILFPPDQFECL	EEE-GGGHHHH	bbbxaaaaaaa
1iyh_A_30	1iyh	A	32	42	HRIEQADWPEI	EEE-GGGHHHH	xbxbaaaaaaa
1jql_B_2	1jql	B	2	12	IRLYPEQLRAQ	EE--GGGHHHH	xbbpaaaaaaa
1jqn_A_608	1jqn	A	610	620	VTEQGEMIRFK	EEE-GGGHHHH	bxxxaaaaaaa
1kkh_A_285	1kkh	A	289	299	ILVNEEKEKEL	EE--GGGHHHH	bxxbaaaaaaa
1kol_A_364	1kol	A	365	375	QVISLDDAPRG	EEE-GGGHHHH	bxbxaaaaaaa
1lci_*_125	1lci	-	126	136	VFVSKKGLQKI	EEE-GGGHHHH	bxbxaaaaaaa
1m4i_A_113	1m4i	A	116	126	LSSSARARRLY	EE--TTTHHHH	bxbxaaaaaaa
1nyr_A_380	1nyr	A	388	398	IFVRPDQIKEE	EEE-GGGHHHH	xbbxaaaaaaa
1o20_A_142	1o20	A	144	154	LRGGSDALNSN	EE--GGGHHHH	bbxxaaaaaaa
1o59_A_3	1o59	A	3	12	.FFSLADEAEF	.EE-GGGHHHH	.bbpaaaaaaa
1od2_A_2112	1od2	A	2112	2121	.ELEWTEARRF	.EE-GGGHHHH	.bbxaaaaaaa
1p0f_A_1344	1p0f	A	1346	1356	TKLTLDQINKA	EEE-GGGHHHH	bbbbaaaaaaa
1pd2_1_30	1pd2	1	32	42	HRIEQADWPKI	EEE-TTTHHHH	xbbxaaaaaaa
1pix_A_540	1pix	A	540	550	EIVDMNKIRGY	EE--TTTHHHH	bxbxaaaaaaa
2fhe_A_27	2fhe	A	30	40	QIYERDDGEKW	EEE-TT-HHHH	xxbxaaaaaaa
3pcg_A_139	3pcg	A	142	152	RLYFDDEAQAN	EEEEGGGHHHH	bbbbaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1b93_A_13	1b93	A	FMTFORMIC ACID	L - 16
1b93_A_13	1b93	A	FMTFORMIC ACID	V - 17
1b93_A_13	1b93	A	FMTFORMIC ACID	A - 18
1b93_A_13	1b93	A	FMTFORMIC ACID	H - 19
1b93_A_13	1b93	A	FMTFORMIC ACID	D - 20
1b93_A_13	1b93	A	FMTFORMIC ACID	K - 23
1b93_A_13	1b93	A	FMTFORMIC ACID	L - 26
1dug_A_28	1dug	A	GSHGLUTHATHIONE	W - 40
1dug_A_28	1dug	A	GSHGLUTHATHIONE	R - 41
1eke_A_20	1eke	A	MSESELENOMETHIONINE	V - 20
1eke_A_20	1eke	A	MSESELENOMETHIONINE	I - 25
1eke_A_20	1eke	A	MSESELENOMETHIONINE	E - 26
1eke_A_20	1eke	A	MSESELENOMETHIONINE	K - 27
1eke_A_20	1eke	A	MSESELENOMETHIONINE	E - 28
1evl_A_378	1evl	A	TSB5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE	F - 379
1evl_A_378	1evl	A	ZNZINC ION	Q - 381
1evl_A_378	1evl	A	TSB5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE	Q - 381
1evl_A_378	1evl	A	ZNZINC ION	D - 383
1evl_A_378	1evl	A	TSB5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE	D - 383
1evl_A_378	1evl	A	ZNZINC ION	A - 384
1evl_A_378	1evl	A	TSB5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE	A - 384
1evl_A_378	1evl	A	ZNZINC ION	H - 385
1evl_A_378	1evl	A	TSB5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE	H - 385
1ez0_A_404	1ez0	A	NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	L - 405
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	Y - 310
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	Y - 311
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	L - 312
1fi4_A_307	1fi4	A	MSESELENOMETHIONINE	A - 313
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	I - 463
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	L - 466
1gx5_A_450	1gx5	A	MSESELENOMETHIONINE	H - 467
1gyx_A_40	1gyx	A	BEZBENZOIC ACID	W - 51
1h2k_A_214	1h2k	A	OGAN-OXALYOLGLYCINE	K - 214
1iyh_A_30	1iyh	A	GSHGLUTHATHIONE	W - 39
1iyh_A_30	1iyh	A	GSHGLUTHATHIONE	K - 43
1jqn_A_608	1jqn	A	DCO3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID	T - 611
1jqn_A_608	1jqn	A	ASPASPARTIC ACID	M - 616
1kol_A_364	1kol	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	F - 379
1m4i_A_113	1m4i	A	COACOENZYME A	L - 116
1m4i_A_113	1m4i	A	KANKANAMYCIN A	L - 116
1m4i_A_113	1m4i	A	COACOENZYME A	S - 117
1m4i_A_113	1m4i	A	KANKANAMYCIN A	S - 117
1m4i_A_113	1m4i	A	COACOENZYME A	S - 118
1m4i_A_113	1m4i	A	KANKANAMYCIN A	S - 118
1m4i_A_113	1m4i	A	COACOENZYME A	S - 119
1m4i_A_113	1m4i	A	KANKANAMYCIN A	S - 119
1m4i_A_113	1m4i	A	KANKANAMYCIN A	A - 120
1m4i_A_113	1m4i	A	COACOENZYME A	R - 121
1m4i_A_113	1m4i	A	COACOENZYME A	A - 122
1m4i_A_113	1m4i	A	COACOENZYME A	R - 124
1m4i_A_113	1m4i	A	COACOENZYME A	L - 125
1m4i_A_113	1m4i	A	COACOENZYME A	Y - 126
1nyr_A_380	1nyr	A	ATPADENOSINE-5'-TRIPHOSPHATE	M - 381
1nyr_A_380	1nyr	A	ATPADENOSINE-5'-TRIPHOSPHATE	L - 383
1nyr_A_380	1nyr	A	THRTHREONINE	L - 383
1nyr_A_380	1nyr	A	ZNZINC ION	D - 385
1nyr_A_380	1nyr	A	THRTHREONINE	D - 385
1nyr_A_380	1nyr	A	ZNZINC ION	S - 386
1nyr_A_380	1nyr	A	THRTHREONINE	S - 386
1nyr_A_380	1nyr	A	ZNZINC ION	H - 387
1nyr_A_380	1nyr	A	THRTHREONINE	H - 387
1o20_A_142	1o20	A	MSESELENOMETHIONINE	L - 143
1o20_A_142	1o20	A	MSESELENOMETHIONINE	L - 144
1o20_A_142	1o20	A	MSESELENOMETHIONINE	R - 145
1o20_A_142	1o20	A	MSESELENOMETHIONINE	I - 157
1o59_A_3	1o59	A	MSESELENOMETHIONINE	F - 3
1od2_A_2112	1od2	A	MSESELENOMETHIONINE	W - 2115
1od2_A_2112	1od2	A	MSESELENOMETHIONINE	F - 2122
1od2_A_2112	1od2	A	MSESELENOMETHIONINE	L - 2126
1od2_A_2112	1od2	A	MSESELENOMETHIONINE	R - 2129
1pd2_1_30	1pd2	1	GTTGLUTATHIONE	W - 39
1pix_A_540	1pix	A	FMTFORMIC ACID	R - 548
1pix_A_540	1pix	A	FMTFORMIC ACID	E - 552

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gyx_A_40	1gyx	A	AC2BEZ BINDING SITE FOR CHAIN A	W - 51

Clusters included in this Subclass