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Information on SUBCLASS 2.1.6
Subclass Accession number: 7128
Subclass: 2.1.6 PSSM
Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 35

Average sequence ID (%) : 11.1 +/- 14.7
Average RMSD (Å) : 0.663 +/- 0.200

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 90-135 rho (°): 180-225
Consensus Sequence: hXXpXX
(φψ)-conformation: bbabaa
Pattern: [afiklmtv][acfgilptv]xx[cdenqrst]x[adeknrst]x[afgiltv]
Conservation:0.729-0.412-0.477-0.6731.954-1.184-0.132-0.7270.923
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4s_A_4051a4s   A409417LPFDTEEEVEEE--HHHHbwbabaaaa
1bcp_A_501bcp   A5260STSSSRRYTEEES-HHHHxbbabaaaa
1bs0_A_1011bs0   A103111LLFISGFAAEEES-HHHHbxbabaaaa
1c30_A_10391c30   A10391047HYDTTLNGGEEESSHHHHxbbabaaaa
1dlj_A_611dlj   A6270KATLDSKAAEEES-HHHHbbbaxaaaa
1f06_A_2581f06   A265273LKLDRNPDFEEES-HHHHbbbabaaaa
1f0x_A_2771f0x   A281289IGTNQPEVLEEES-HHHHbbbabaaaa
1f0y_A_881f0y   A8997ATSTDAASVEEES-HHHHxbbabaaaa
1gg4_A_771gg4   A7886LIVKDTRLAEEES-HHHHbxbabaaaa
1ghs_A_1431ghs   A143150.VFKNAYMT.EESSTHHH.bxaxaaaa
1i1q_A_2671i1q   A272280LPCPSPLAAEE-S-HHHHbwbabaaaa
1i3j_A_2101i3j   A210218VIFDCAADAEEESSHHHHxxbabaaaa
1inl_A_1161inl   A119127LCEVDGLVIEEES-HHHHbbbabaaaa
1inp_*_3731inp   -374382IAYRSEKQLEEES-HHHHbxbabaaaa
1iy9_A_1021iy9   A105113LVDIDGKVIEEES-HHHHbbbaxaaaa
1jf8_A_771jf8   A7886VVTLCSDADEEE-SHHHHbbxabaaaa
1jl3_A_771jl3   A7886VVTLCGDAAEEE-SHHHHbbxabaaaa
1jr2_A_1921jr2   A193201ITFFSPSGLEEESSHHHHbbbabaaaa
1jr2_A_581jr2   A5967LIFTSPRAVEEE--HHHHbbbabaaaa
1js3_A_1411js3   A143151VIQGSASEAEEES-HHHHbxbabaaaa
1k3y_A_311k3y   A3341KFIKSAEDLEEE-SHHHHbxxabaaaa
1k8t_A_6021k8t   A603611ILTKNWEMTEEESSHHHHbbxabaaaa
1kcf_A_2041kcf   A204212ILFENEEALEEESSHHHHbbbabaaaa
1kmv_A_881kmv   A8896FLSRSLDDAEEESSHHHHbbbabaaaa
1lg2_A_1791lg2   A183191AVPAGQTYVEEE--HHHHxbxaxaaaa
1mjf_A_991mjf   A102110MVEIDEDVIEEES-HHHHbbbabaaaa
1mpy_A_51mpy   A1321LRVLDMSKAEEES-HHHHbxbabaaaa
1mxi_A_581mxi   A5866KRHKTFEAFEEESSHHHHbbbabaaaa
1o7d_A_1161o7d   A116124FIYVEIAFFEEE--HHHHbbbaxaaaa
1ohv_A_1291ohv   A131139ITMACGSCSEEESSHHHHbxbabaaaa
1qgo_A_371qgo   A4048RAFTSGMIIEEE--HHHHbbbaxaaaa
1ra9_*_731ra9   -7381TWVKSVDEAEEESSHHHHbbbabaaaa
1toh_*_4311toh   -433441FVSESFNDAEEES-HHHHbbxabaaaa
2oat_A_1352oat   A137145LPMNTGVEAEEESSHHHHbxbabaaaa
4gsa_A_1164gsa   A118126RFVNSGTEAEEESSHHHHbxbabaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1c30_A_10391c30   A     ORNORNITHINE H - 1039
1c30_A_10391c30   A     ORNORNITHINE Y - 1040
1c30_A_10391c30   A     ORNORNITHINE D - 1041
1c30_A_10391c30   A     ORNORNITHINE T - 1042
1c30_A_10391c30   A     ORNORNITHINE T - 1043
1c30_A_10391c30   A     ORNORNITHINE G - 1046
1dlj_A_611dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE S - 67
1dlj_A_611dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE Y - 71
1f06_A_2581f06   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 270
1f06_A_2581f06   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE P - 271
1f06_A_2581f06   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE T - 274
1gg4_A_771gg4   A     MSESELENOMETHIONINE F - 87
1gg4_A_771gg4   A     MSESELENOMETHIONINE L - 90
1gg4_A_771gg4   A     MSESELENOMETHIONINE A - 91
1gg4_A_771gg4   A     MSESELENOMETHIONINE V - 94
1jf8_A_771jf8   A     BCTBICARBONATE ION C - 82
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE G - 146
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE S - 147
1js3_A_1411js3   A     142CARBIDOPA S - 147
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE A - 148
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE S - 149
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE E - 150
1js3_A_1411js3   A     PLPPYRIDOXAL-5'-PHOSPHATE T - 152
1k3y_A_311k3y   A     GTXS-HEXYLGLUTATHIONE L - 41
1k3y_A_311k3y   A     GTXS-HEXYLGLUTATHIONE R - 45
1kmv_A_881kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 90
1kmv_A_881kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 91
1kmv_A_881kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 92
1kmv_A_881kmv   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 93
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL A - 183
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL V - 184
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL P - 185
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL A - 186
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL G - 187
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL Q - 188
1lg2_A_1791lg2   A     EDO1,2-ETHANEDIOL Y - 190
1ohv_A_1291ohv   A     FEFE (III) ION M - 133
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE A - 134
1ohv_A_1291ohv   A     FEFE (III) ION A - 134
1ohv_A_1291ohv   A     SSULFUR ATOM A - 134
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE C - 135
1ohv_A_1291ohv   A     FEFE (III) ION C - 135
1ohv_A_1291ohv   A     SSULFUR ATOM C - 135
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE G - 136
1ohv_A_1291ohv   A     FEFE (III) ION G - 136
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE S - 137
1ohv_A_1291ohv   A     FEFE (III) ION S - 137
1ohv_A_1291ohv   A     SSULFUR ATOM S - 137
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE C - 138
1ohv_A_1291ohv   A     FEFE (III) ION C - 138
1ohv_A_1291ohv   A     SSULFUR ATOM C - 138
1ohv_A_1291ohv   A     FEFE (III) ION S - 139
1ohv_A_1291ohv   A     PLPPYRIDOXAL-5'-PHOSPHATE N - 140
1ra9_*_731ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 75
1ra9_*_731ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE K - 76
1ra9_*_731ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 77
1ra9_*_731ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 78
2oat_A_1352oat   A     PFM1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE N - 140
2oat_A_1352oat   A     PFM1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE T - 141
2oat_A_1352oat   A     PFM1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE G - 142
2oat_A_1352oat   A     PFM1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE V - 143
2oat_A_1352oat   A     PFM1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE E - 144
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE N - 121
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE S - 122
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE G - 123
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE T - 124
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE E - 125
4gsa_A_1164gsa   A     PLPPYRIDOXAL-5'-PHOSPHATE C - 127
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1ohv_A_1291ohv   A AC4S BINDING SITE FOR CHAIN AA - 134
1ohv_A_1291ohv   A AC2PLP BINDING SITE FOR CHAIN AC - 135
1ohv_A_1291ohv   A AC2PLP BINDING SITE FOR CHAIN AG - 136
1ohv_A_1291ohv   A AC2PLP BINDING SITE FOR CHAIN AS - 137
1ohv_A_1291ohv   A AC3FE BINDING SITE FOR CHAIN AC - 138
1ohv_A_1291ohv   A AC2PLP BINDING SITE FOR CHAIN AN - 140

Clusters included in this Subclass
CLUSTER: EH.1.21
CLUSTER: EH.1.64
CLUSTER: EH.2.28
CLUSTER: EH.3.161
CLUSTER: EH.3.171