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Information on SUBCLASS 2.2.3
Subclass Accession number: 4564
Subclass: 2.2.3 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 36

Average sequence ID (%) : 13.9 +/- 18.5
Average RMSD (Å) : 0.614 +/- 0.187

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: XXXXXX
(φψ)-conformation: aalpaa
Pattern: x[acgstv][acfgilmvwy]xx[adgknqs][adgnstv][dehknpqrt]x[acfgilvy][acfiklmtv]
Conservation:-0.8800.8840.0530.094-0.3162.466-0.318-0.369-1.405-0.008-0.202
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1awc_B_1401awc   B143153ISIDNGNEDLAHHHHTT-HHHHaaaaavxaaaa
1bd8_*_1421bd8   -145155LALQRGAQDLVHHHHS--HHHHaxGaavxaaaa
1bsg_*_1191bsg   -125135VSITASDNCAAHHHHS--HHHHaaaaalxaaaa
1bue_A_1191bue   A125135AALQYSDNGATHHHHS--HHHHaaaaalpaaaa
1dcq_A_4521dcq   A455465YCCLTDNAECLHHHHTT-HHHHaaaaalxaaaa
1dja_*_1191dja   -125135ASMTYSDNTANHHHHS--HHHHaaaaalxaaaa
1e25_A_1191e25   A125135YSVSHSDNVACHHHHH--HHHHaaaaalxaaaa
1ed8_A_3251ed8   A328338KQDHAANPCGQHHHHTT-HHHHaaaaalbaaaa
1fi4_A_2391fi4   A239249KAIVEKDFATFHHHHTT-HHHHaaaaalxaaaa
1fo3_A_4021fo3   A408418LSRLTGDKKFQHHHHH--THHHaaaaavxaaaa
1g6a_A_1191g6a   A125135ATMTTSDNTAAHHHHH--HHHHaaaaavpaaaa
1g9g_A_4131g9g   A425435LYYKTGDARAKHHHHH--HHHHaaaaavpaaaa
1gyt_A_2251gyt   A227237QMKELGMHSYLHHHHTT-HHHHaaaaavxaaaa
1hs6_A_5321hs6   A541551LCIQSKWEDAIHHHHTT-TTHHaaaaavxaaaa
1hzo_A_1191hzo   A125135ATLQYSDNTAMHHHHT--HHHHaaaaavxaaaa
1i2s_A_1191i2s   A125135ASLRYSDNTAQHHHHH--HHHHaaaaalxaaaa
1i5n_A_371i5n   A5363GAGTFGFTILQHHHHTT-HHHHaaaaavxaaaa
1ikn_D_2201ikn   D223233LAVDLQNPDLVHHHHTT-HHHHaaaaalbaaaa
1ixv_A_391ixv   A4252WSVSFQAHEITHHHHTT-HHHHaaaaalxaaaa
1k55_A_1081k55   A110120GAIQVSAVPVFHHHHTT-HHHHaaaaalxaaaa
1kre_A_2031kre   A209219LSDLTGDEEYAHHHHHS-THHHaaaaavxaaaa
1l0l_K_81l0l   K3242LVWATDWRLILHHHHHT-HHHHaaaaalpaaaa
1m56_C_1341m56   C154164ALVHENNRRDVHHHHT--HHHHaaaaavxaaaa
1m6k_A_1081m6k   A110120TWMQFSVVWVSHHHHTT-HHHHaaaaalxaaaa
1mfo_A_1191mfo   A125135AALQRSDNTAAHHHHS--HHHHaaaaalpaaaa
1n9b_A_1191n9b   A125135AAITMSDNSAAHHHHH--HHHHaaaaavxaaaa
1nrf_A_4431nrf   A445455SAMSSSTTWYFHHHHHT-HHHHaaaaalxaaaa
1nzo_A_991nzo   A105115GINLQSGNDACHHHTT--HHHHaaaaalxaaaa
1o7e_A_1191o7e   A125135ATIITSDNTAAHHHHS--HHHHaaaaavpaaaa
1ot8_A_871ot8   A90100AAVAADAMGVFHHHHTT-HHHHaaaaalxaaaa
1ouv_A_2641ouv   A270280KGCKLGAKGACHHHHHT-HHHHaaaaagxaaaa
1pqm_A_1161pqm   A119129RMLQQKRWDEAHHHHHTT-HHHaaaaavxaaaa
1qme_A_3881qme   A390400QGFAHSSNVGMHHHHTT-HHHHaaaaalxaaaa
1rj1_A_841rj1   A90100EALTKGDPKFAHHHHHT-THHHaaaaavbaaaa
1ut9_A_5611ut9   A571581LYVTTGKDEYKHHHHH--HHHHaaaaavxaaaa
2erl_*_22erl   -515QAAIQCVESACHHHHTT-HHHHaaaaavbaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ed8_A_3251ed8   A     ZNZINC ION D - 327
1ed8_A_3251ed8   A     MGMAGNESIUM ION D - 327
1ed8_A_3251ed8   A     PO4PHOSPHATE ION D - 327
1ed8_A_3251ed8   A     ZNZINC ION K - 328
1ed8_A_3251ed8   A     MGMAGNESIUM ION K - 328
1ed8_A_3251ed8   A     PO4PHOSPHATE ION K - 328
1ed8_A_3251ed8   A     ZNZINC ION H - 331
1ed8_A_3251ed8   A     PO4PHOSPHATE ION H - 331
1fi4_A_2391fi4   A     MSESELENOMETHIONINE K - 239
1fi4_A_2391fi4   A     MSESELENOMETHIONINE A - 240
1fi4_A_2391fi4   A     MSESELENOMETHIONINE I - 241
1fi4_A_2391fi4   A     MSESELENOMETHIONINE V - 242
1fi4_A_2391fi4   A     MSESELENOMETHIONINE F - 246
1fi4_A_2391fi4   A     MSESELENOMETHIONINE A - 247
1fi4_A_2391fi4   A     MSESELENOMETHIONINE T - 248
1fi4_A_2391fi4   A     MSESELENOMETHIONINE F - 249
1fi4_A_2391fi4   A     MSESELENOMETHIONINE A - 250
1fi4_A_2391fi4   A     MSESELENOMETHIONINE K - 251
1fi4_A_2391fi4   A     MSESELENOMETHIONINE E - 252
1hs6_A_5321hs6   A     IMDIMIDAZOLE R - 537
1hzo_A_1191hzo   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID Y - 129
1hzo_A_1191hzo   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID S - 130
1i2s_A_1191i2s   A     CITCITRIC ACID Y - 129
1i2s_A_1191i2s   A     CITCITRIC ACID S - 130
1i2s_A_1191i2s   A     CITCITRIC ACID N - 132
1i5n_A_371i5n   A     MSESELENOMETHIONINE I - 43
1i5n_A_371i5n   A     MSESELENOMETHIONINE A - 46
1i5n_A_371i5n   A     MSESELENOMETHIONINE A - 47
1i5n_A_371i5n   A     MSESELENOMETHIONINE I - 50
1i5n_A_371i5n   A     MSESELENOMETHIONINE L - 62
1i5n_A_371i5n   A     MSESELENOMETHIONINE E - 64
1i5n_A_371i5n   A     MSESELENOMETHIONINE T - 65
1i5n_A_371i5n   A     MSESELENOMETHIONINE T - 66
1i5n_A_371i5n   A     MSESELENOMETHIONINE H - 67
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID A - 111
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID I - 112
1k55_A_1081k55   A     SULSULFATE ANION I - 112
1k55_A_1081k55   A     SULSULFATE ANION Q - 113
1k55_A_1081k55   A     SULSULFATE ANION V - 114
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID S - 115
1k55_A_1081k55   A     SULSULFATE ANION S - 115
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID A - 116
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID V - 117
1k55_A_1081k55   A     SULSULFATE ANION V - 117
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID F - 120
1k55_A_1081k55   A     KCXLYSINE NZ-CARBOXYLIC ACID Q - 121
1k55_A_1081k55   A     SULSULFATE ANION R - 125
1k55_A_1081k55   A     SULSULFATE ANION V - 127
1m56_C_1341m56   C     PEHDI-STEAROYL-3-SN-PHOSPHATIDYLETHANOLAMINE T - 149
1m56_C_1341m56   C     PEHDI-STEAROYL-3-SN-PHOSPHATIDYLETHANOLAMINE H - 152
1m6k_A_1081m6k   A     KCXLYSINE NZ-CARBOXYLIC ACID W - 111
1m6k_A_1081m6k   A     KCXLYSINE NZ-CARBOXYLIC ACID M - 112
1m6k_A_1081m6k   A     KCXLYSINE NZ-CARBOXYLIC ACID F - 114
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL F - 114
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL S - 115
1m6k_A_1081m6k   A     KCXLYSINE NZ-CARBOXYLIC ACID V - 116
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL V - 117
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL W - 118
1m6k_A_1081m6k   A     KCXLYSINE NZ-CARBOXYLIC ACID S - 120
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL E - 122
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL I - 123
1m6k_A_1081m6k   A     MPD2-METHYL-2,4-PENTANEDIOL K - 126
1n9b_A_1191n9b   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID M - 129
1n9b_A_1191n9b   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID S - 130
1o7e_A_1191o7e   A     GOLGLYCEROL G - 140
1o7e_A_1191o7e   A     GOLGLYCEROL V - 141
1o7e_A_1191o7e   A     GOLGLYCEROL V - 142
1ot8_A_871ot8   A     MGMAGNESIUM ION M - 97
1ot8_A_871ot8   A     MGMAGNESIUM ION Q - 101
1pqm_A_1161pqm   A     PO4PHOSPHATE ION K - 124
1pqm_A_1161pqm   A     PO4PHOSPHATE ION R - 125
1pqm_A_1161pqm   A     PO4PHOSPHATE ION W - 126
1pqm_A_1161pqm   A     PO4PHOSPHATE ION D - 127
1pqm_A_1161pqm   A     PO4PHOSPHATE ION E - 128
1pqm_A_1161pqm   A     PO4PHOSPHATE ION A - 129
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1o7e_A_1191o7e   A AC1GOL BINDING SITE FOR CHAIN AG - 140

Clusters included in this Subclass
CLUSTER: HH.1.114
CLUSTER: HH.2.46
CLUSTER: HH.3.210
CLUSTER: HH.3.26
CLUSTER: HH.4.21