ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 2.1.4

Subclass Accession number: 1044
Subclass: 2.1.4

Type: EH beta-alpha
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Number of loops: 37

Average sequence ID (%) : 9.6 +/- 13.7
Average RMSD (Å) : 0.581 +/- 0.200

Consensus geometry

d (Å): 7

delta (°): 0-45

theta (°): 135-180

rho (°): 45-90

Consensus Sequence:	XhXpXX
(φψ)-conformation:	bbabaa

Pattern:	x	[acfilptv]	x	[dgnrst]	x	[adegknqrst]	[adegknqst]	x
Conservation:	0.143	-0.467	-1.286	1.505	-1.362	0.670	0.731	0.066

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a9x_A_1039	1a9x	A	1040	1047	YDTTLNGG	EESSHHHH	bbabaaaa
1a9x_A_725	1a9x	A	727	734	IVYDEADL	EE-SHHHH	bxabaaaa
1b74_A_65	1b74	A	67	74	VVACNTAS	EE--HHHH	bxaxaaaa
1ct5_A_108	1ct5	A	113	120	TIDSLKKA	EE-SHHHH	axabaaaa
1dlj_A_61	1dlj	A	63	70	ATLDSKAA	EES-HHHH	bbaxaaaa
1ed8_A_235	1ed8	A	236	243	LVSDAASL	EE-SHHHH	bbabaaaa
1edq_A_358	1edq	A	363	370	ISAGKDKI	EE-SHHHH	bpaxaaaa
1euc_B_22	1euc	B	24	31	VADTANEA	EESSHHHH	bbabaaaa
1ewq_A_154	1ewq	A	159	166	VLKSKSAL	EESSHHHH	bbabaaaa
1f60_A_111	1f60	A	116	123	IAGGVGEF	EE-SHHHH	bxapaaaa
1fvi_A_140	1fvi	A	141	148	EINNITEL	EE-SHHHH	xbabaaaa
1gvf_A_78	1gvf	A	83	90	HHESLDDI	EE--HHHH	lxabaaaa
1h1d_A_85	1h1d	A	89	96	MEMNPDYA	EE--HHHH	xbaxaaaa
1h4v_B_331	1h4v	B	334	341	IPLTEEAV	EESSHHHH	bxabaaaa
1hkk_A_179	1hkk	A	184	191	VPAGQTYV	EE--HHHH	bxaxaaaa
1htw_A_3	1htw	A	7	14	YIPDEFSM	EE-SHHHH	xbabaaaa
1jfl_A_189	1jfl	A	191	198	IAGCTEVS	EE-SHHHH	xxabaaaa
1jr2_A_192	1jr2	A	194	201	TFFSPSGL	EESSHHHH	bbabaaaa
1jr2_A_58	1jr2	A	60	67	IFTSPRAV	EE--HHHH	bbabaaaa
1k3y_A_31	1k3y	A	34	41	FIKSAEDL	EE-SHHHH	xxabaaaa
1k66_A_35	1k66	A	37	44	RCITGDQA	EE-SHHHH	bbabaaaa
1kbi_A_346	1kbi	A	350	357	GVQRTEDV	EE-SHHHH	gxabaaaa
1l6w_A_106	1l6w	A	110	117	AVYGAAQG	EE-SHHHH	lxabaaaa
1mty_D_444	1mty	D	447	454	TFSDQWGE	EESSHHHH	bbabaaaa
1mw5_A_123	1mw5	A	127	134	LPESFAAR	EESSHHHH	bxaxaaaa
1n2z_A_26	1n2z	A	27	34	ITLSPANT	EE-SHHHH	bbabaaaa
1naq_A_11	1naq	A	17	24	TAPDEATA	EESSHHHH	bbabaaaa
1ny5_A_26	1ny5	A	29	36	SAERGKEA	EESSHHHH	bbabaaaa
1o88_A_19	1o88	A	22	29	TATSMQDI	EESSHHHH	bbabaaaa
1oki_A_118	1oki	A	119	126	EYPRWNTW	EE-SHHHH	bbabaaaa
1onr_A_153	1onr	A	157	164	LLFSFAQA	EE-SHHHH	lxabaaaa
1p4c_A_227	1p4c	A	232	239	GLLSAEDA	EE--HHHH	gxabaaaa
1p99_A_139	1p99	A	142	149	IPNDVSNQ	EE-SHHHH	bxaxaaaa
1q7z_A_142	1q7z	A	147	154	TFSDILEL	EE--HHHH	lxabaaaa
1r4p_A_223	1r4p	A	224	231	SFNNISAI	EE-SHHHH	bbabaaaa
1urs_A_325	1urs	A	325	332	IPALLSVQ	EESSHHHH	xxaxaaaa
2bop_A_370	2bop	A	379	386	TFGSPSQR	EESSHHHH	bbabaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a9x_A_725	1a9x	A	ADPADENOSINE-5'-DIPHOSPHATE	M - 725
1a9x_A_725	1a9x	A	ADPADENOSINE-5'-DIPHOSPHATE	I - 727
1a9x_A_1039	1a9x	A	ORNORNITHINE	H - 1039
1a9x_A_1039	1a9x	A	ORNORNITHINE	Y - 1040
1a9x_A_1039	1a9x	A	ORNORNITHINE	D - 1041
1a9x_A_1039	1a9x	A	ORNORNITHINE	T - 1042
1a9x_A_1039	1a9x	A	ORNORNITHINE	T - 1043
1a9x_A_1039	1a9x	A	ORNORNITHINE	G - 1046
1b74_A_65	1b74	A	DGND-GLUTAMINE	A - 69
1b74_A_65	1b74	A	DGND-GLUTAMINE	C - 70
1b74_A_65	1b74	A	DGND-GLUTAMINE	N - 71
1b74_A_65	1b74	A	DGND-GLUTAMINE	T - 72
1ct5_A_108	1ct5	A	MSESELENOMETHIONINE	E - 112
1ct5_A_108	1ct5	A	MSESELENOMETHIONINE	T - 113
1ct5_A_108	1ct5	A	PLPPYRIDOXAL-5'-PHOSPHATE	T - 113
1dlj_A_61	1dlj	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	S - 67
1dlj_A_61	1dlj	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	Y - 71
1ewq_A_154	1ewq	A	EDO1,2-ETHANEDIOL	A - 165
1ewq_A_154	1ewq	A	EDO1,2-ETHANEDIOL	D - 168
1ewq_A_154	1ewq	A	EDO1,2-ETHANEDIOL	E - 169
1ewq_A_154	1ewq	A	MSESELENOMETHIONINE	R - 172
1ewq_A_154	1ewq	A	EDO1,2-ETHANEDIOL	R - 172
1gvf_A_78	1gvf	A	EGLETHYLENE GLYCOL	A - 78
1gvf_A_78	1gvf	A	EGLETHYLENE GLYCOL	L - 79
1gvf_A_78	1gvf	A	PGCO-PHOSPHOGLYCOLOHYDROXAMATE	D - 82
1gvf_A_78	1gvf	A	ZNZINC ION	D - 82
1gvf_A_78	1gvf	A	PGCO-PHOSPHOGLYCOLOHYDROXAMATE	H - 83
1gvf_A_78	1gvf	A	ZNZINC ION	H - 83
1gvf_A_78	1gvf	A	EGLETHYLENE GLYCOL	V - 94
1gvf_A_78	1gvf	A	EGLETHYLENE GLYCOL	H - 95
1h1d_A_85	1h1d	A	SAMS-ADENOSYLMETHIONINE	M - 89
1h1d_A_85	1h1d	A	SAMS-ADENOSYLMETHIONINE	E - 90
1h1d_A_85	1h1d	A	SAMS-ADENOSYLMETHIONINE	M - 91
1h1d_A_85	1h1d	A	SAMS-ADENOSYLMETHIONINE	N - 92
1h1d_A_85	1h1d	A	SAMS-ADENOSYLMETHIONINE	Y - 95
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	A - 183
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	P - 185
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	A - 186
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	G - 187
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	Q - 188
1hkk_A_179	1hkk	A	AMIALLOSAMIZOLINE	Y - 190
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	I - 8
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	P - 9
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	D - 10
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	E - 11
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	F - 12
1htw_A_3	1htw	A	ADPADENOSINE-5'-DIPHOSPHATE	M - 14
1k3y_A_31	1k3y	A	GTXS-HEXYLGLUTATHIONE	L - 41
1k3y_A_31	1k3y	A	GTXS-HEXYLGLUTATHIONE	R - 45
1kbi_A_346	1kbi	A	FMNFLAVIN MONONUCLEOTIDE	K - 349
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	R - 353
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	T - 354
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	E - 355
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	D - 356
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	I - 358
1kbi_A_346	1kbi	A	MPD2-METHYL-2,4-PENTANEDIOL	K - 359
1l6w_A_106	1l6w	A	GOLGLYCEROL	L - 107
1l6w_A_106	1l6w	A	GOLGLYCEROL	T - 109
1mw5_A_123	1mw5	A	MSESELENOMETHIONINE	Y - 124
1mw5_A_123	1mw5	A	MSESELENOMETHIONINE	L - 126
1mw5_A_123	1mw5	A	MSESELENOMETHIONINE	L - 127
1mw5_A_123	1mw5	A	MSESELENOMETHIONINE	P - 128
1mw5_A_123	1mw5	A	MSESELENOMETHIONINE	L - 137
1n2z_A_26	1n2z	A	CNCCO-CYANOCOBALAMIN	L - 29
1n2z_A_26	1n2z	A	CNCCO-CYANOCOBALAMIN	S - 30
1n2z_A_26	1n2z	A	CNCCO-CYANOCOBALAMIN	P - 31
1n2z_A_26	1n2z	A	CNCCO-CYANOCOBALAMIN	A - 32
1n2z_A_26	1n2z	A	CNCCO-CYANOCOBALAMIN	N - 33
1naq_A_11	1naq	A	HGMERCURY (II) ION	C - 16
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	C - 16
1naq_A_11	1naq	A	HGMERCURY (II) ION	T - 17
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	T - 17
1naq_A_11	1naq	A	HGMERCURY (II) ION	A - 18
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	A - 18
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	P - 19
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	T - 23
1naq_A_11	1naq	A	HGMERCURY (II) ION	L - 27
1naq_A_11	1naq	A	MBOMERCURIBENZOIC ACID	L - 27
1p4c_A_227	1p4c	A	FMNFLAVIN MONONUCLEOTIDE	K - 231
1p99_A_139	1p99	A	METMETHIONINE	D - 145
1p99_A_139	1p99	A	METMETHIONINE	S - 147
1p99_A_139	1p99	A	METMETHIONINE	N - 148
1p99_A_139	1p99	A	METMETHIONINE	R - 151
1q7z_A_142	1q7z	A	CDCADMIUM ION	T - 147
1r4p_A_223	1r4p	A	FMTFORMIC ACID	I - 223
1r4p_A_223	1r4p	A	FMTFORMIC ACID	S - 224

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gvf_A_78	1gvf	A	AC1PGC BINDING SITE FOR CHAIN A	D - 82
1gvf_A_78	1gvf	A	AC1PGC BINDING SITE FOR CHAIN A	H - 83
1hkk_A_179	1hkk	A	AC3AMI BINDING SITE FOR CHAIN A	A - 183
1hkk_A_179	1hkk	A	AC6AMI BINDING SITE FOR CHAIN A	A - 186
1hkk_A_179	1hkk	A	AC6AMI BINDING SITE FOR CHAIN A	G - 187
1hkk_A_179	1hkk	A	AC6AMI BINDING SITE FOR CHAIN A	Y - 190

Clusters included in this Subclass