ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 1.1.16

Subclass Accession number: 2645
Subclass: 1.1.16

Type: EH beta-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Number of loops: 27

Average sequence ID (%) : 11.1 +/- 16.6
Average RMSD (Å) : 0.504 +/- 0.151

Consensus geometry

d (Å): 11

delta (°): 0-45

theta (°): 90-135

rho (°): 270-315

Consensus Sequence:	XXXXX
(φψ)-conformation:	bbpaa

Pattern:	x	[fhilmvy]	[aegkqrst]	[afilmtv]	[adpst]	x	[adest]	[cdenqry]	[acfgilvy]
Conservation:	-1.507	1.294	-0.352	0.162	0.626	-0.968	1.402	-0.773	0.116

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bwv_A_130	1bwv	A	137	145	DMRLPLAYL	EEE--HHHH	bbbbxaaaa
1cgt_*_17	1cgt	-	17	25	IYQVFTDRF	EEE--HHHH	xbxbxaaaa
1cuk_*_24	1cuk	-	27	35	EVHMPMTCF	EEE--HHHH	xbxbxaaaa
1dyt_A_40	1dyt	A	43	51	FLRTTFANV	EESS-HHHH	xxxbbaaaa
1e4i_A_11	1e4i	A	13	21	GTATAAYQI	EEE--HHHH	bbbbbaaaa
1e4m_M_30	1e4m	M	32	40	GVASSAYQI	EEE--HHHH	bbbbbaaaa
1gk8_A_130	1gk8	A	137	145	DLRIPPAYV	EEE--HHHH	bbxxxaaaa
1gnx_A_23	1gnx	A	25	33	GSATASYQI	EEE--HHHH	bbbbbaaaa
1gu7_A_317	1gu7	A	318	326	SAGFWVTEL	EEE--HHHH	bbbbbaaaa
1hrk_A_257	1hrk	A	262	270	AHSLPMSVV	EE--BHHHH	bpxbxaaaa
1hsl_A_46	1hsl	A	47	55	FVENPLDAL	EEE--HHHH	xxxbwaaaa
1jey_B_319	1jey	B	320	328	IVPFSKVDE	EEE--HHHH	bbwbxaaaa
1jqe_A_111	1jqe	A	115	123	WHKETSSEY	EE-S-HHHH	bbxbxaaaa
1ky8_A_377	1ky8	A	378	386	LVEAPADRV	EEE--HHHH	bbxbxaaaa
1l4u_A_97	1l4u	A	99	107	YLEISAAEG	EEE--HHHH	xxxbxaaaa
1mdo_A_299	1mdo	A	300	308	IIRVDEARC	EEE--HHHH	xbxbxaaaa
1n8q_A_315	1n8q	A	315	322	.IKLPTDII	.EE--HHHH	.bxbxaaaa
1nki_A_65	1nki	A	66	74	AFGIAAADF	EEE--HHHH	bbxbxaaaa
1npb_A_68	1npb	A	69	77	AFTVAEEDF	EEE--HHHH	xbxbxaaaa
1qme_A_369	1qme	A	369	377	ATIRDWDVN	EEE--HHHH	xbxbxaaaa
1rbl_A_130	1rbl	A	137	145	DIRFPVALV	EEE--HHHH	bbxxxaaaa
1rsy_*_205	1rsy	-	211	219	TFKVPYSEL	EE---HHHH	bbxbxaaaa
1vcc_*_41	1vcc	-	45	53	VYEQTWEEA	EE---HHHH	bxxbxaaaa
1via_A_95	1via	A	98	106	YLKADFEYL	EEE--HHHH	xxbbxaaaa
2aaa_*_11	2aaa	-	11	19	IYFLLTDRF	EEE--HHHH	bbxbxaaaa
5rub_A_118	5rub	A	125	133	DFYVPEAYR	EEE--HHHH	bbbbxaaaa
8ruc_A_130	8ruc	A	137	145	DLRIPVAYV	EEE--HHHH	bbxxxaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dyt_A_40	1dyt	A	CITCITRIC ACID	Q - 40
1dyt_A_40	1dyt	A	CITCITRIC ACID	N - 41
1dyt_A_40	1dyt	A	CITCITRIC ACID	L - 44
1dyt_A_40	1dyt	A	CITCITRIC ACID	R - 45
1dyt_A_40	1dyt	A	CITCITRIC ACID	T - 46
1dyt_A_40	1dyt	A	CITCITRIC ACID	T - 47
1dyt_A_40	1dyt	A	CITCITRIC ACID	N - 50
1dyt_A_40	1dyt	A	CITCITRIC ACID	V - 51
1dyt_A_40	1dyt	A	CITCITRIC ACID	N - 53
1dyt_A_40	1dyt	A	CITCITRIC ACID	V - 54
1e4i_A_11	1e4i	A	G2F2-DEOXY-2FLUORO-GLUCOSE	A - 17
1e4i_A_11	1e4i	A	G2F2-DEOXY-2FLUORO-GLUCOSE	Q - 20
1e4m_M_30	1e4m	M	GOLGLYCEROL	S - 36
1e4m_M_30	1e4m	M	GOLGLYCEROL	Q - 39
1gk8_A_130	1gk8	A	SMCS-METHYLCYSTEINE	P - 142
1gk8_A_130	1gk8	A	SMCS-METHYLCYSTEINE	V - 145
1gu7_A_317	1gu7	A	GOLGLYCEROL	A - 319
1gu7_A_317	1gu7	A	GOLGLYCEROL	G - 320
1gu7_A_317	1gu7	A	GOLGLYCEROL	F - 321
1gu7_A_317	1gu7	A	GOLGLYCEROL	W - 322
1gu7_A_317	1gu7	A	GOLGLYCEROL	V - 323
1gu7_A_317	1gu7	A	GOLGLYCEROL	T - 324
1gu7_A_317	1gu7	A	GOLGLYCEROL	E - 325
1gu7_A_317	1gu7	A	GOLGLYCEROL	L - 326
1gu7_A_317	1gu7	A	GOLGLYCEROL	L - 327
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	H - 263
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	S - 264
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	L - 265
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	P - 266
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	S - 268
1hrk_A_257	1hrk	A	CHDCHOLIC ACID	V - 269
1jqe_A_111	1jqe	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	E - 118
1jqe_A_111	1jqe	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	T - 119
1jqe_A_111	1jqe	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	S - 120
1jqe_A_111	1jqe	A	SAHS-ADENOSYL-L-HOMOCYSTEINE	S - 121
1l4u_A_97	1l4u	A	ADPADENOSINE-5'-DIPHOSPHATE	L - 100
1l4u_A_97	1l4u	A	PTPLATINUM (II) ION	A - 104
1l4u_A_97	1l4u	A	ADPADENOSINE-5'-DIPHOSPHATE	E - 106
1l4u_A_97	1l4u	A	ADPADENOSINE-5'-DIPHOSPHATE	R - 110
1mdo_A_299	1mdo	A	MSESELENOMETHIONINE	F - 299
1mdo_A_299	1mdo	A	MSESELENOMETHIONINE	I - 301
1nki_A_65	1nki	A	MNMANGANESE (II) ION	A - 66
1via_A_95	1via	A	MSESELENOMETHIONINE	L - 106

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1gu7_A_317	1gu7	A	AC2GOL BINDING SITE FOR CHAIN A	F - 321
1gu7_A_317	1gu7	A	AC2GOL BINDING SITE FOR CHAIN A	W - 322
1gu7_A_317	1gu7	A	AC4GOL BINDING SITE FOR CHAIN A	T - 324
1gu7_A_317	1gu7	A	AC2GOL BINDING SITE FOR CHAIN A	E - 325
1gu7_A_317	1gu7	A	AC7GOL BINDING SITE FOR CHAIN A	L - 326
1gu7_A_317	1gu7	A	AC4GOL BINDING SITE FOR CHAIN A	L - 327

Clusters included in this Subclass

CLUSTER: EH.1.45

CLUSTER: EH.2.28

CLUSTER: EH.3.39