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Information on SUBCLASS 2.4.2
Subclass Accession number: 541
Subclass: 2.4.2 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 50

Average sequence ID (%) : 9.6 +/- 13.2
Average RMSD (Å) : 0.296 +/- 0.114

Consensus geometry
d (Å): 7 delta (°): 90-135 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: XXpXXX
(φψ)-conformation: bbllbb
Pattern: xxxx[adegknqrs][ADGKNQRST]xx
Conservation:-1.000-0.676-0.678-0.3750.5642.049-0.303-0.579
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ac5_*_4301ac5   -432439VKYDRNLTEEEETTEEbbbblvbb
1bag_*_4021bag   -403410FQVNDGKLEEE-SSEEbbxbllbx
1ccz_A_331ccz   A3643AELENSEFEEEETTEEbbbblvbb
1eaj_A_691eaj   A7279ILYSGDKIEEEETTEEbbbblvbb
1ei5_A_2701ei5   A270275..YGFGLN..EETTEE..bblvbx
1el6_A_1711el6   A171177.YSTYGIT.EEETTEE.bbblvxx
1epa_A_371epa   A4148VELKENLLEEEETTEEbbbblvbb
1et9_A_1001et9   A105112NVWDKSKQEEEETTEEbxbxlgxx
1eu3_A_391eu3   A3945.DVRDARD.EEETTEE.ebblvxx
1ewk_A_4921ewk   A498505GTWHEGVLEEEETTEEbbbblvbx
1exm_A_2631exm   A269276GVEMHRKTEEEETTEEbbbblvbx
1f5n_A_111f5n   A1421IENTNGRLEEEETTEEbxbblvbb
1f97_A_681f97   A7178LVCYNSQIEEEETTEExabblvbx
1gkp_A_4341gkp   A435442VAVRDGQFEEEETTEExabblvbx
1gl4_A_5401gl4   A544551YHYSSSVIEEEETTEEbxbblvbb
1gzq_A_1211gzq   A124131LSVKNASCEEEETTEEbbbxlUbx
1h0b_A_611h0b   A6471FGCHWGACEEEETTEEbebblvxb
1hp1_A_4741hp1   A477484DLKIKGEPEEEETTEElxbblvbx
1hq8_A_1201hq8   A120126.ICHRNNC.EEETTEE.xbblvxb
1htr_B_781htr   B8895TLTVQSIQEEEETTEExxbbvvxb
1i24_A_1601i24   A162169TITHNGRTEEEETTEExbbblvbb
1iby_A_41iby   A1724ELNVEGVTEEEETTEEbxbblvbb
1j34_A_71j34   A713.SSYEGHC.EEETTEE.bxblvbb
1j54_A_301j54   A3643VEVVNRRLEEEETTEEbxbbllbx
1jzn_A_81jzn   A814.LPMNGLC.EEETTEE.xwblvbb
1k3b_A_671k3b   A6976EIVLNDYKEEEETTEEbbbblvbb
1kcx_A_4511kcx   A452459IVFEDGNIEEEETTEExabblvbx
1kmv_A_1701kmv   A170176.QEEKGIK.EEETTEE.bbblvbx
1kwa_A_5351kwa   A536543IREINGISEEEETTEExabblvxx
1lp8_A_2201lp8   A220225..CKNGVF..EETTEE..bblvbx
1mju_H_1771mju   H177183.VLQSDLY.EEETTEE.bbbvvbx
1n7e_A_7181n7e   A719726ILAINSSSEEEETTEExabblvxx
1neu_*_481neu   -5158FHYAKGQPEEEETTEEbbbblvbx
1nqe_A_4131nqe   A423430EGLTAGVNEEEETTEEbbbblvbx
1nsc_A_2291nsc   A229235.NCIGGDC.EEETTEE.bbblvxb
1obb_A_2041obb   A209216RFRYNGGNEEEETTEEbbbbvvbx
1ocv_A_721ocv   A7278.RAVANEA.EEETTEE.bbblUbb
1oxx_K_671oxx   K6875LVASNGKLEEEETTEExabblvbx
1oz9_A_771oz9   A7782..EFGGYK..EETTEE..bblgxb
1pz7_A_1731pz7   A178185DVIVDRQEEEEETTEElxbblvbx
1qdd_A_191qdd   A1925.NAYRSYC.EEETTEE.bxblvbb
1r6j_A_2361r6j   A238245ICEINGQNEEEETTEExabblvxx
1ryb_A_411ryb   A4147.TIQSKSL.EEETTEE.bbbllbb
1sh0_A_3891sh0   A389394..TFLRRT..EETTEE..bblvbx
1ukm_B_61ukm   B612.SSFDQHC.EEETTEE.bxblvbb
1uuh_A_291uuh   A2934..RFAGVF..EETTEE..xblvxb
1vhz_A_491vhz   A5360VPIVDDHLEEEETTEEbwbbllbx
1who_*_451who   -4552TKGEGGVWEE-STTEEbxxxvvxb
2nlr_A_592nlr   A6269NGCHYTNCEEEETTEEbebblvxb
4cd2_A_1904cd2   A190196.INEDGFD.EEETTEE.bbblvbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ac5_*_4301ac5   *     NAGN-ACETYL-D-GLUCOSAMINE Y - 434
1ac5_*_4301ac5   *     NAGN-ACETYL-D-GLUCOSAMINE D - 435
1ac5_*_4301ac5   *     NAGN-ACETYL-D-GLUCOSAMINE R - 436
1ac5_*_4301ac5   *     NAGN-ACETYL-D-GLUCOSAMINE N - 437
1gzq_A_1211gzq   A     D12DODECANE F - 123
1gzq_A_1211gzq   A     TWTDOCOSANE F - 123
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE L - 124
1gzq_A_1211gzq   A     TWTDOCOSANE L - 124
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE S - 125
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE V - 126
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE A - 129
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE S - 130
1gzq_A_1211gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE C - 131
1h0b_A_611h0b   A     EPE4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID W - 68
1iby_A_41iby   A     CUCOPPER (II) ION I - 8
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL A - 10
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL I - 15
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL L - 18
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL V - 20
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL I - 28
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL F - 31
1iby_A_41iby   A     CUCOPPER (II) ION V - 33
1iby_A_41iby   A     HEZHEXANE-1,6-DIOL V - 33
1j34_A_71j34   A     CACALCIUM ION H - 12
1j34_A_71j34   A     CACALCIUM ION Y - 14
1j54_A_301j54   A     TMPTHYMIDINE-5'-PHOSPHATE I - 31
1j54_A_301j54   A     EGLETHYLENE GLYCOL V - 38
1j54_A_301j54   A     EGLETHYLENE GLYCOL V - 39
1j54_A_301j54   A     EGLETHYLENE GLYCOL N - 40
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE G - 420
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE A - 421
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE F - 422
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE E - 423
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE W - 431
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE R - 432
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE I - 433
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE S - 434
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE G - 435
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE Y - 436
1nqe_A_4131nqe   A     C8E(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE R - 437
1nsc_A_2291nsc   A     NAGN-ACETYL-D-GLUCOSAMINE I - 231
1nsc_A_2291nsc   A     SIAO-SIALIC ACID T - 240
1nsc_A_2291nsc   A     SIAO-SIALIC ACID G - 242
1obb_A_2041obb   A     CSWCYSTEINE-S-DIOXIDE I - 205
1oxx_K_671oxx   K     IODIODIDE ION R - 67
1oxx_K_671oxx   K     IODIODIDE ION V - 69
1oxx_K_671oxx   K     IODIODIDE ION L - 75
1uuh_A_291uuh   A     MSESELENOMETHIONINE V - 33
2nlr_A_592nlr   A     GLCGLUCOSE S - 59
2nlr_A_592nlr   A     GLCGLUCOSE H - 65
2nlr_A_592nlr   A     G2F2-DEOXY-2FLUORO-GLUCOSE H - 65
2nlr_A_592nlr   A     GLCGLUCOSE Y - 66
2nlr_A_592nlr   A     G2F2-DEOXY-2FLUORO-GLUCOSE Y - 66
2nlr_A_592nlr   A     GLCGLUCOSE N - 68
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gzq_A_1211gzq   A AC6TWT BINDING SITE FOR CHAIN AF - 123

Clusters included in this Subclass
CLUSTER: HA.1.70
CLUSTER: HA.1.9
CLUSTER: HA.1.91
CLUSTER: HA.2.110
CLUSTER: HA.2.15
CLUSTER: HA.3.130
CLUSTER: HA.3.18
CLUSTER: HA.3.187
CLUSTER: HA.3.193