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Information on SUBCLASS 2.8.1
Subclass Accession number: 8287
Subclass: 2.8.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 24

Average sequence ID (%) : 16.4 +/- 17.0
Average RMSD (Å) : 0.558 +/- 0.222

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 90-135 rho (°): 180-225
Consensus Sequence: XhXGpX
(φψ)-conformation: aapgbb
Pattern: x[adegkqrst]x[filtvwy]x[DGNR][ehknqs][adekqrt][filmv]x
Conservation:-0.468-0.122-0.763-0.174-0.6492.498-0.006-0.3140.834-0.836
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a2z_A_191a2z   A2432AKYFDRKQI.HHHHTT-EE.aaaapvxbb.
1ayl_*_991ayl   -110119TRQLSGKRLFHHHHTTS-EEaaaaxvbxbb
1b0z_A_1171b0z   A124133LDVLEGKDLSHHHHTT--EEaaaapvbxbb
1d2n_A_6961d2n   A703712AQQVKGKKVWHHHHTTSEEEaaaapgxxbb
1df7_A_251df7   A3241REITMGHTIVHHHHTTSEEEaaaapvbxbb
1ee8_A_31ee8   A1423RPLVLGQTLRHHHHTT-EEEaaaapvxxxa
1f2v_A_1251f2v   A125134SERLAGSVVAHHHHTT-EEEaaaapvxbxb
1fsg_A_491fsg   A6473HRTYFGEELHHHHHTTS-EEaaaapvxxbb
1g24_A_1521g24   A159168KAKFLNKDRLHHHHTT-EEEaaaapvbxbb
1i8t_A_1941i8t   A199208EKMLEGVDVKHHHHTTSEEEaaaapvbxbb
1iof_A_181iof   A2331AKDLDGIKI.HHHHTT-EE.aaaaxvxbb.
1j54_A_791j54   A8796MDYIRGAELVHHHHTTSEEEaaaapvxxxb
1jdr_A_2551jdr   A268275KLLENGIT..HHHHTTEE..aaaapvbx..
1l4u_A_861l4u   A8998RAALAGHTVVHHHHTTS-EEaaaapgxxbx
1m1n_B_3421m1n   B359368HTWLHGKRFAHHHHTT-EEEaaaapvxbbb
1mfo_A_1071mfo   A109118TEARAGAEMTHHHTTTSEEEaaaapvbbbx
1nnj_A_371nnj   A4150KKELTGKTIQHHHHTT-BEEaaaaxvxbxa
1oal_A_1141oal   A114123LKELKGHAIMHHHHTT-EEEaaaapvxbbb
1orr_A_2561orr   A256265VSKIRGNAFNHHHHTT-EEEaaaapvbbbx
1qcs_A_1191qcs   A122131IQQFNNQAFSHHHHTT-EEEaaaaxvbxbb
1qgu_B_3381qgu   B355364HTWLHGKKFGHHHHTT-EEEaaaaxvxbbx
1ra9_*_251ra9   -3241KRNTLDKPVIHHHHTTS-EEaaaaplbxbb
2ptd_*_1512ptd   -151160LGDARGKIVLHHHHTTSEEEaaaapvbbbx
2scu_B_662scu   B7381AENWLGKRL.HHHHTTSEE.aaaapvxbb.
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1d2n_A_6961d2n   A     GOLGLYCEROL D - 696
1d2n_A_6961d2n   A     GOLGLYCEROL K - 697
1d2n_A_6961d2n   A     GOLGLYCEROL E - 698
1d2n_A_6961d2n   A     GOLGLYCEROL T - 700
1df7_A_251df7   A     MTXMETHOTREXATE P - 25
1df7_A_251df7   A     GOLGLYCEROL P - 25
1df7_A_251df7   A     MTXMETHOTREXATE E - 26
1df7_A_251df7   A     GOLGLYCEROL E - 26
1df7_A_251df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 27
1df7_A_251df7   A     MTXMETHOTREXATE D - 27
1df7_A_251df7   A     GOLGLYCEROL D - 27
1df7_A_251df7   A     MTXMETHOTREXATE Q - 28
1df7_A_251df7   A     GOLGLYCEROL Q - 28
1df7_A_251df7   A     MTXMETHOTREXATE A - 29
1df7_A_251df7   A     GOLGLYCEROL A - 29
1df7_A_251df7   A     MTXMETHOTREXATE H - 30
1df7_A_251df7   A     GOLGLYCEROL H - 30
1df7_A_251df7   A     MTXMETHOTREXATE F - 31
1df7_A_251df7   A     MTXMETHOTREXATE R - 32
1df7_A_251df7   A     GOLGLYCEROL E - 33
1df7_A_251df7   A     MTXMETHOTREXATE T - 35
1df7_A_251df7   A     MTXMETHOTREXATE M - 36
1df7_A_251df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE M - 42
1df7_A_251df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 43
1fsg_A_491fsg   A     MO2MAGNESIUM ION, 2 WATERS COORDINATED I - 77
1fsg_A_491fsg   A     PRPALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID I - 77
1fsg_A_491fsg   A     MO2MAGNESIUM ION, 2 WATERS COORDINATED L - 78
1fsg_A_491fsg   A     PRPALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC ACID L - 78
1j54_A_791j54   A     EGLETHYLENE GLYCOL G - 92
1j54_A_791j54   A     EGLETHYLENE GLYCOL A - 93
1j54_A_791j54   A     MNMANGANESE (II) ION I - 97
1jdr_A_2551jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 262
1jdr_A_2551jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 266
1jdr_A_2551jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 269
1l4u_A_861l4u   A     ADPADENOSINE-5'-DIPHOSPHATE L - 100
1m1n_B_3421m1n   B     CACALCIUM ION D - 353
1m1n_B_3421m1n   B     CACALCIUM ION M - 354
1m1n_B_3421m1n   B     CACALCIUM ION T - 356
1m1n_B_3421m1n   B     CACALCIUM ION D - 357
1oal_A_1141oal   A     CUCOPPER (II) ION M - 123
1oal_A_1141oal   A     CUCOPPER (II) ION I - 124
1oal_A_1141oal   A     CUCOPPER (II) ION H - 125
1qcs_A_1191qcs   A     MSESELENOMETHIONINE A - 119
1qcs_A_1191qcs   A     MSESELENOMETHIONINE E - 120
1qcs_A_1191qcs   A     MSESELENOMETHIONINE F - 121
1qcs_A_1191qcs   A     MSESELENOMETHIONINE I - 122
1qcs_A_1191qcs   A     MSESELENOMETHIONINE F - 130
1qgu_B_3381qgu   B     MO2MAGNESIUM ION, 2 WATERS COORDINATED D - 349
1qgu_B_3381qgu   B     MO2MAGNESIUM ION, 2 WATERS COORDINATED M - 350
1qgu_B_3381qgu   B     MO2MAGNESIUM ION, 2 WATERS COORDINATED D - 353
1qgu_B_3381qgu   B     EDO1,2-ETHANEDIOL T - 356
1qgu_B_3381qgu   B     EDO1,2-ETHANEDIOL W - 357
1qgu_B_3381qgu   B     EDO1,2-ETHANEDIOL K - 361
1ra9_*_251ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE M - 42
1ra9_*_251ra9   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 43
2scu_B_662scu   B     COACOENZYME A K - 66
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1oal_A_1141oal   A AC2CU BINDING SITE FOR CHAIN AH - 125

Clusters included in this Subclass
CLUSTER: HE.2.31
CLUSTER: HE.3.180
CLUSTER: HE.3.51
CLUSTER: HE.3.96
CLUSTER: HE.4.299
CLUSTER: HE.4.90
CLUSTER: HE.4.91
CLUSTER: HE.5.222