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Information on SUBCLASS 3.1.3
Subclass Accession number: 5452
Subclass: 3.1.3 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 44

Average sequence ID (%) : 14.4 +/- 16.3
Average RMSD (Å) : 0.798 +/- 0.162

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXGXXXX
(φψ)-conformation: aagpabb
Pattern: x[deknqrsty][adegknqrs]x[degknqr]x[deknpqrst]xxxx
Conservation:0.3170.0800.462-0.7672.525-0.6820.672-0.917-0.616-0.538-0.537
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aye_*_2541aye   -258268SYDYGIKYSFAHHHTT-SEEEEaaaagxaxbbb
1b37_A_141b37   A2333LSEAGITDLLIHHHTT---EEEaaaavxaxbbb
1b43_A_1741b43   A175185SLLFGAPRLVRHHHTT-SEEEEaaaavxwbbbb
1bpy_A_1791bpy   A180188SFRRGAESS..HHHTT-SEE..aaaaUpabx..
1brm_A_751brm   A8595LRESGWQGYWIHHTTT---EEEaaaavpaxxbb
1dtd_A_6101dtd   A614624SYDYGIKYSFAHHHHT--EEEEaaaagxaxbbb
1e0c_A_2351e0c   A243253AKALGYPRVKGHHHTT-S-EEEaaaavxabbbb
1e0c_A_931e0c   A102112LDVIGQQRYHYHHHTT---EEEaaaavxaxbbb
1eq2_A_101eq2   A1929LNDKGITDILVHHTTT---EEEaaaavbaxbbx
1gyt_A_2951gyt   A307317VAELQLPINVIHHHHT-SSEEEaaaalxabbbb
1h7w_A_1971h7w   A206216LARLGYSDITIHHHHT---EEEaaaagxabbbb
1hrk_A_3561hrk   A357367AKECGVENIRRHHHTT-SEEEEaaaavxabbbb
1hxh_A_1491hxh   A169179CRKQGYAIRVNHHHHT--EEEEaaaavxabbbb
1jbe_A_921jbe   A98108AAQAGASGYVVHHHTT-SEEEEaaaagxabepx
1jkx_A_1201jkx   A124134ALENGDEEHGTHHHTT-SEEEEaaaavxabbeb
1kek_A_871kek   A100110ISGELLPGVFHHHHTT---EEEaaaalbaxbxb
1kwm_A_2541kwm   A258268AYDQGIRYSFTHHHTT-SEEEEaaaagxabbbb
1ll2_A_131ll2   A2636LKQHRTSRRLAHHHTT--SEEEaaaalxaxxbb
1lss_A_761lss   A8696AKSYGINKTIAHHHTT---EEEaaaagxaxbbb
1m2k_A_1031m2k   A104114HERAGSRNVIHHHHTT--SEEEaaaagxabbbx
1m4l_A_2541m4l   A258268SYNQGIKYSFTHHHTT--EEEEaaaavxaxbbb
1ma3_A_1051ma3   A106116HQRAGSRRVLEHHHHT--SEEEaaaagxaxbbx
1mb4_A_741mb4   A8494LRQAGWKGYWIHHHTT--SEEEaaaavxaxxbb
1mbx_C_781mbx   C92102ARENEHPLLCTHHHTT---EEEaaaalbaxbbb
1np6_A_601np6   A6070LRKAGAAQTIVHHHHT-SEEEEaaaagxabbbb
1npy_A_1311npy   A138148FKNSGFEKLKIHHHTT---EEEaaaavxabbbb
1nsa_*_2541nsa   -258268AYNQGIKYSFTHHHTT-S-EEEaaaagxabbbb
1nwc_A_761nwc   A8696LKATGWDGYWVHHHTT--SEEEaaaavpaxbbb
1nx9_A_3441nx9   A352362LKDADVKAPNTHHHTT-SS-EEaaaalpabwbb
1nyt_A_2211nyt   A226235CEQRGSKRNA.HHHTT--EEE.aaaagxabbb.
1obb_A_421obb   A5666VEEVGADLKFEHHHTT---EEEaaaavxaxbbb
1p77_A_2221p77   A227236CKSLGLTNVS.HHHTT---EE.aaaavxaxbb.
1pfk_A_1751pfk   A181190AIAGGCEFVV.HHHTT-SEEE.aaaavxabbb.
1q1r_A_141q1r   A2333LRASGWEGNIRHHHTT--SEEEaaaavxaxxbb
1qgo_A_1491qgo   A162172MTAQRFPARVGHHHHT-SEEEEaaaavxabbbb
1qjw_A_1421qjw   A155165ANKNGGNYAGQHHHTT--EEEEaaaavxaxbxb
1qmg_A_1361qmg   A148158LTEAKSDVVVKHHHTT---EEEaaaavxaxxbb
1qyi_A_3511qyi   A354363LEAHHADYVI.HHHTT-SEEE.aaaalxabbb.
1rhs_*_1081rhs   -115125FRVFGHRTVSVHHHTT---EEEaaaavbaxbbb
1rzt_A_4161rzt   A417425SYRRGKATC..HHHTT-SEE..aaaavxabb..
1usg_A_2031usg   A213223ARSVGLKTQFMHHHTT---EEEaaaavxapxbb
1v8f_A_1471v8f   A157167VRDLGFPVEVVHHHHT---EEEaaaavxabxxx
1vjt_A_411vjt   A5564VEELNSPVKI.HHHHT---EE.aaaalxapxb.
3pfk_*_1753pfk   -181190GLAGGAETIL.HHHHT-SEEE.aaaavxabbb.
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1b37_A_141b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE M - 14
1b37_A_141b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 15
1b37_A_141b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 16
1b37_A_141b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 34
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE G - 179
1bpy_A_1791bpy   A     MGMAGNESIUM ION G - 179
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE S - 180
1bpy_A_1791bpy   A     MGMAGNESIUM ION S - 180
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE F - 181
1bpy_A_1791bpy   A     MGMAGNESIUM ION F - 181
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE R - 183
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE S - 187
1bpy_A_1791bpy   A     DCT2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE S - 188
1bpy_A_1791bpy   A     MGMAGNESIUM ION S - 188
1dtd_A_6101dtd   A     GLUGLUTAMIC ACID S - 610
1dtd_A_6101dtd   A     GLUGLUTAMIC ACID I - 611
1dtd_A_6101dtd   A     GLUGLUTAMIC ACID A - 624
1dtd_A_6101dtd   A     ZNZINC ION E - 626
1dtd_A_6101dtd   A     GLUGLUTAMIC ACID E - 626
1e0c_A_931e0c   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED W - 94
1e0c_A_2351e0c   A     CSSS-MERCAPTOCYSTEINE R - 235
1e0c_A_2351e0c   A     CSSS-MERCAPTOCYSTEINE S - 236
1e0c_A_2351e0c   A     CSSS-MERCAPTOCYSTEINE G - 237
1eq2_A_101eq2   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 10
1eq2_A_101eq2   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 11
1eq2_A_101eq2   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 12
1eq2_A_101eq2   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 30
1eq2_A_101eq2   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 31
1gyt_A_2951gyt   A     ZNZINC ION N - 325
1h7w_A_1971h7w   A     FADFLAVIN-ADENINE DINUCLEOTIDE P - 197
1h7w_A_1971h7w   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 198
1h7w_A_1971h7w   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 199
1h7w_A_1971h7w   A     FADFLAVIN-ADENINE DINUCLEOTIDE F - 217
1h7w_A_1971h7w   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 218
1jkx_A_1201jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE T - 120
1jkx_A_1201jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE H - 121
1jkx_A_1201jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE T - 134
1jkx_A_1201jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE H - 137
1kek_A_871kek   A     HTL2-ACETYL-THIAMINE DIPHOSPHATE Q - 88
1kek_A_871kek   A     HTL2-ACETYL-THIAMINE DIPHOSPHATE G - 89
1kek_A_871kek   A     HTL2-ACETYL-THIAMINE DIPHOSPHATE L - 92
1ll2_A_131ll2   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Y - 15
1lss_A_761lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE E - 77
1lss_A_761lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 78
1lss_A_761lss   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 97
1m4l_A_2541m4l   A     ZNZINC ION E - 270
1mb4_A_741mb4   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 74
1mbx_C_781mbx   C     GOLGLYCEROL A - 78
1mbx_C_781mbx   C     GOLGLYCEROL E - 79
1mbx_C_781mbx   C     GOLGLYCEROL A - 81
1mbx_C_781mbx   C     GOLGLYCEROL E - 82
1mbx_C_781mbx   C     GOLGLYCEROL L - 103
1obb_A_421obb   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 44
1pfk_A_1751pfk   A     ADPADENOSINE-5'-DIPHOSPHATE G - 184
1pfk_A_1751pfk   A     MGMAGNESIUM ION G - 184
1pfk_A_1751pfk   A     ADPADENOSINE-5'-DIPHOSPHATE G - 185
1pfk_A_1751pfk   A     MGMAGNESIUM ION G - 185
1pfk_A_1751pfk   A     ADPADENOSINE-5'-DIPHOSPHATE C - 186
1pfk_A_1751pfk   A     MGMAGNESIUM ION C - 186
1pfk_A_1751pfk   A     ADPADENOSINE-5'-DIPHOSPHATE E - 187
1pfk_A_1751pfk   A     MGMAGNESIUM ION E - 187
1q1r_A_141q1r   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 14
1q1r_A_141q1r   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 15
1q1r_A_141q1r   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 35
1qjw_A_1421qjw   A     CDCADMIUM ION E - 146
1qjw_A_1421qjw   A     MANALPHA-D-MANNOSE G - 159
1qjw_A_1421qjw   A     MANALPHA-D-MANNOSE G - 160
1qjw_A_1421qjw   A     MANALPHA-D-MANNOSE N - 161
1qjw_A_1421qjw   A     MANALPHA-D-MANNOSE Y - 162
1qmg_A_1361qmg   A     DMV2,3-DIHYDROXY-VALERIANIC ACID Q - 136
1qmg_A_1361qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE Q - 136
1qmg_A_1361qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE A - 137
1qmg_A_1361qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE P - 138
1qmg_A_1361qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE Q - 140
1qmg_A_1361qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE L - 161
1v8f_A_1471v8f   A     144TRIS-HYDROXYMETHYL-METHYL-AMMONIUM Q - 149
1v8f_A_1471v8f   A     GOLGLYCEROL V - 169
1vjt_A_411vjt   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 43
1vjt_A_411vjt   A     MSESELENOMETHIONINE L - 44
1vjt_A_411vjt   A     MSESELENOMETHIONINE S - 47
1vjt_A_411vjt   A     MSESELENOMETHIONINE Y - 48
1vjt_A_411vjt   A     MSESELENOMETHIONINE A - 51
1vjt_A_411vjt   A     MSESELENOMETHIONINE K - 53
1vjt_A_411vjt   A     MSESELENOMETHIONINE E - 57
1vjt_A_411vjt   A     MSESELENOMETHIONINE I - 64
3pfk_*_1753pfk   *     PO4PHOSPHATE ION G - 184
3pfk_*_1753pfk   *     PO4PHOSPHATE ION G - 185
3pfk_*_1753pfk   *     PO4PHOSPHATE ION A - 186
3pfk_*_1753pfk   *     PO4PHOSPHATE ION E - 187
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1aye_*_2541aye   * 1SUBSITE S1: ARG 145, ASN 144, TYR 248 SUBSITE S1: ARG 127, GLU 270 SUBSITE S2: ARG 71, SER 197, TYR 198, SER 199 SUBSITE S3: PHE 279 SUBSITE S4: LYS 122, ARG 124, LYS 128.E - 270
1h7w_A_1971h7w   A AC6FAD BINDING SITE FOR CHAIN AP - 197
1h7w_A_1971h7w   A AC6FAD BINDING SITE FOR CHAIN AA - 198
1h7w_A_1971h7w   A AC6FAD BINDING SITE FOR CHAIN AE - 218
1obb_A_421obb   A AC1NAD BINDING SITE FOR CHAIN AR - 44

Clusters included in this Subclass
CLUSTER: HE.2.98
CLUSTER: HE.3.144
CLUSTER: HE.3.64
CLUSTER: HE.4.101
CLUSTER: HE.4.251
CLUSTER: HE.4.257
CLUSTER: HE.4.296
CLUSTER: HE.4.359
CLUSTER: HE.4.46
CLUSTER: HE.5.173
CLUSTER: HE.5.53
CLUSTER: HE.5.65
CLUSTER: HE.6.182
CLUSTER: HE.6.41