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Information on SUBCLASS 1.1.2
Subclass Accession number: 2631
Subclass: 1.1.2 PSSM
Type: EH beta-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 102

Average sequence ID (%) : 8.1 +/- 12.2
Average RMSD (Å) : 0.522 +/- 0.177

Consensus geometry
d (Å): 7 delta (°): 0-45 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: XhXXX
(φψ)-conformation: bbpaa
Pattern: xxxxxxx[acfgiklmtv]
Conservation:-1.000-0.9651.7780.010-1.044-0.138-0.4260.785
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a2p_A_241a2p   A2430.YITKSEA.EE-HHHH.xbxaaaa
1a4m_A_2581a4m   A259266FEVCPWSSEEE-HHHHbxxbaaaa
1ag9_A_611ag9   A6167.EAQCDWD.EE-HHHH.xxpaaaa
1al3_*_921al3   -97104VATTHTQAEEE-HHHHbbbbaaaa
1amx_*_2601amx   -263270VTIPQGYGEEE-HHHHbbbwaaaa
1auo_A_781auo   A7884.SISLEEL.EE-HHHH.xbxaaaa
1b7y_B_4041b7y   B404411IPFRPEYAEEE-HHHHbwbbaaaa
1bf2_*_1811bf2   -182189YEVHVRGFEEE-HHHHbxbxaaaa
1bu6_O_1801bu6   O180186.VTDYTNA.EE-HHHH.bbxaaaa
1bue_A_1801bue   A180186.TSTPAAV.EE-HHHH.bbbaaaa
1buo_A_441buo   A4552FHAHRTVLEEE-HHHHbxbbaaaa
1c1k_A_1961c1k   A197204LNIDSQKAEEE-HHHHxxbxaaaa
1cr5_A_781cr5   A7986IGFNGNQREEE-HHHHbxbxaaaa
1cyo_*_61cyo   -612.YYTLEEI.EE-HHHH.bbxaaaa
1d2n_A_7101d2n   A711718VWIGIKKLEEE-HHHHbbbxaaaa
1dbx_A_1351dbx   A137144VEIAPQDLEEE-HHHHbbbpaaaa
1ddg_A_4151ddg   A416423ARAGGASSEEE-HHHHxbbxaaaa
1deu_A_731deu   A7379.GGNDLSV.EE-HHHH.ebbaaaa
1df9_A_451df9   A4653FHTMWHVTEEE-HHHHxxbxaaaa
1dms_*_6681dms   -669676CLMHPDDAEEE-HHHHbxbxaaaa
1eg7_A_13271eg7   A13301337IVATVRALEEE-HHHHbxbbaaaa
1ekb_B_511ekb   B5259LVSAAHCVEEE-HHHHbbbxaaaa
1ekm_A_3161ekm   A316322.HALDIGE.EE-HHHH.axbaaaa
1eys_C_191eys   C2027NYYVKRQREEE-HHHHbbbxaaaa
1f20_A_12061f20   A12061213VHHGVCSSEEE-HHHHxbbpaaaa
1fm0_E_501fm0   E5259LEHYPGMTEEE-HHHHbxbbaaaa
1fus_*_91fus   -916TNYSASQVEEE-HHHHxbbxaaaa
1g57_A_671g57   A6875LCITEDRREEE-HHHHbxbxaaaa
1g5a_A_1001g5a   A101108GVCYVDLFEEE-HHHHbbbxaaaa
1g6g_A_461g6g   A4855LSADISQVEEE-HHHHxbbbaaaa
1g8k_A_7271g8k   A728735IEMNPDDCEEE-HHHHbxbxaaaa
1gjw_A_861gjw   A8794YGSLPRTTEEE-HHHHbxbbaaaa
1gpr_*_1111gpr   -113120LEVDLDAVEEE-HHHHbbbxaaaa
1gt9_1_41gt9   1411TAYTPLDVEEE-HHHHbbbxaaaa
1gz0_F_491gz0   F5158QLANRQYLEEE-HHHHbxbxaaaa
1h0h_A_8811h0h   A882889CEMSEELAEEE-HHHHbxbxaaaa
1h16_A_6661h16   A667674FSIVPNALEEE-HHHHbbbxaaaa
1h1n_A_471h1n   A5057VPFMMERLEEE-HHHHbwbxaaaa
1hrd_A_3651hrd   A365372VVAPSKAVEEE-HHHHbbbxaaaa
1hzo_A_1801hzo   A180186.TTSPIAM.EE-HHHH.bbbaaaa
1i2s_A_1801i2s   A180186.TSTARAL.EE-HHHH.bbbaaaa
1icc_C_61icc   C612.YYRLEEV.EE-HHHH.bbxaaaa
1ig0_A_3041ig0   A308315VEIFVDKLEEE-HHHHbxbbaaaa
1ioo_A_1301ioo   A130137SSYTFQDIEEE-HHHHbbbxaaaa
1ioo_A_41ioo   A815VLTWPASFEEE-HHHHbbxxaaaa
1iwe_A_2321iwe   A232238.VRDGVYF.EE-HHHH.xbxaaaa
1iz0_A_271iz0   A3542VGLNFADHEEE-HHHHbxxbaaaa
1j3b_A_761j3b   A7683QPFAPEAFEEE-HHHHxxbxaaaa
1jd0_A_2161jd0   A216223VQISQEQLEEE-HHHHbbbxaaaa
1jey_A_3251jey   A327334IILEKEETEEE-HHHHbbbxaaaa
1jti_A_271jti   A2734IFYCPIAIEEE-HHHHbbbbaaaa
1jv1_A_3921jv1   A395402YEVLREDEEEE-HHHHbxbxaaaa
1k1x_A_461k1x   A4855VHFSGPLLEEE-HHHHbbbxaaaa
1k4i_A_661k4i   A6774APLTPERTEEE-HHHHbwbxaaaa
1k6d_A_51k6d   A511.LMTLQDA.EE-HHHH.xbbaaaa
1ko3_A_1351ko3   A136143TYASPSTREEE-HHHHxbbxaaaa
1kq3_A_311kq3   A3441VVIDDFVDEEE-HHHHbbbxaaaa
1kqf_A_9191kqf   A920927VEISETLAEEE-HHHHbbbxaaaa
1ksi_A_2971ksi   A297303.TFFDSGE.EE-HHHH.bpbaaaa
1kv7_A_3471kv7   A353360LSMDPMLDEEE-HHHHxbbpaaaa
1kwg_A_2611kwg   A263270WDSYPLGFEEE-HHHHbbxbaaaa
1kzl_A_1791kzl   A182189VEVDQIGKEEE-THHHbbxpaaaa
1lci_*_4471lci   -447454YQVAPAELEEE-HHHHxxbxaaaa
1lf2_A_2201lf2   A220227ITVPTDFLEEE-HHHHxbbxaaaa
1lj5_A_321lj5   A3239VVFSPYGVEEE-HHHHbbbbaaaa
1ljp_A_811ljp   A8187.VLDVYTY.EE-HHHH.bbxaaaa
1lm5_A_26681lm5   A26682674.KLSLQDA.EE-HHHH.xbxaaaa
1lm5_A_27821lm5   A27822788.KISYKDA.EE-HHHH.xbxaaaa
1lri_A_811lri   A8187.VLNVYSY.EE-HHHH.bbxaaaa
1ls6_A_181ls6   A1825VPLIKYFAEEE-HHHHbwbxaaaa
1lug_A_2141lug   A215222ISVSSEQVEE-HHHHHxxbxaaaa
1m3u_A_2101m3u   A211218QILVMHDAEEE-HHHHbbbxaaaa
1n6a_A_2481n6a   A248255VRITHQEVEEE-HHHHxbbxaaaa
1n7v_A_1151n7v   A115121.SPNAASI.EE-HHHH.bxxaaaa
1n8n_A_221n8n   A2229HWVSVAQIEEE-HHHHxxbbaaaa
1n9b_A_1801n9b   A180186.TTTPASM.EE-HHHH.bbbaaaa
1n9l_A_341n9l   A3542VYASEGFYEEE-HHHHabbxaaaa
1ndy_A_2581ndy   A259266FEICPWSSEEE-HHHHbxxbaaaa
1nf9_A_1981nf9   A198205MVVTTDEVEEE-HHHHxbbxaaaa
1nn7_A_501nn7   A5259FQTWQDTLEEE-HHHHbbbbaaaa
1npy_A_961npy   A98105RAYNTDYIEEE-HHHHbbbbaaaa
1nyt_A_741nyt   A7480.ELTERAA.EE-HHHH.bbxaaaa
1obo_A_10611obo   A10611067.ELQSDWE.EE-HHHH.bxxaaaa
1p77_A_741p77   A7480.EYSQRAK.EE-HHHH.bbxaaaa
1p99_A_2031p99   A204211AVINNGVAEEE-HHHHbxbxaaaa
1pp7_U_651pp7   U6572FKMKKKNVEEE-HHHHbbbbaaaa
1q16_A_6031q16   A603610RHMNSTSYEEE-HHHHbxbxaaaa
1qw2_A_911qw2   A9197.EASQEAQ.EE-HHHH.bbxaaaa
1qy6_A_451qy6   A4653LLTNKHVVEEE-HHHHbbbxaaaa
1r29_A_411r29   A4350FRAHKTVLEEE-HHHHbxbbaaaa
1rhs_*_91rhs   -915.LVSTKWL.EE-HHHH.bbxaaaa
1rvk_A_2781rvk   A279286LRTGVNDVEEE-HHHHxbbbaaaa
1sh0_A_1831sh0   A185192WGSDLATMEE--HHHHbxxxaaaa
1uca_A_31uca   A714VQQWPPAVEEE-HHHHbbbxaaaa
1vjf_A_1131vjf   A115122FVLDKALAEEEBHHHHbbbpaaaa
1yac_A_1611yac   A161168QLMTWFGVEEE-HHHHxxbbaaaa
2hgs_A_2342hgs   A235242IRRTFEDIEEE-HHHHbbbxaaaa
2hgs_A_562hgs   A5662.LVPSALL.EE-HHHH.xbpaaaa
3tss_*_1233tss   -123129.QLAISTL.EE-HHHH.bbxaaaa
4nos_A_4334nos   A433439.IMDHHSA.EE-HHHH.bbxaaaa
4pep_*_2464pep   -246252.VISCSSI.EE-THHH.pbxaaaa
7taa_*_117taa   -1219YFLLTDRFEEE-HHHHbxbbaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a4m_A_2581a4m   A     ZNZINC ION C - 262
1a4m_A_2581a4m   A     PRH6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE C - 262
1a4m_A_2581a4m   A     PRH6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE S - 265
1ag9_A_611ag9   A     FMNFLAVIN MONONUCLEOTIDE E - 61
1ag9_A_611ag9   A     CACALCIUM ION E - 61
1ag9_A_611ag9   A     FMNFLAVIN MONONUCLEOTIDE Q - 63
1ag9_A_611ag9   A     CACALCIUM ION C - 64
1ag9_A_611ag9   A     CACALCIUM ION D - 67
1ag9_A_611ag9   A     CACALCIUM ION D - 68
1c1k_A_1961c1k   A     IRIRIDIUM ION K - 203
1cr5_A_781cr5   A     NEN1-ETHYL-PYRROLIDINE-2,5-DIONE G - 80
1d2n_A_7101d2n   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER I - 715
1d2n_A_7101d2n   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 716
1d2n_A_7101d2n   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER L - 719
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 418
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 419
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 420
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 421
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 422
1ddg_A_4151ddg   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 423
1ekb_B_511ekb   B     ZNZINC ION W - 51
1ekb_B_511ekb   B     CH2METHYLENE GROUP A - 55
1ekb_B_511ekb   B     CH2METHYLENE GROUP H - 57
1ekb_B_511ekb   B     CH2METHYLENE GROUP C - 58
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE H - 1208
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 1209
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 1210
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE C - 1211
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 1212
1f20_A_12061f20   A     FADFLAVIN-ADENINE DINUCLEOTIDE S - 1213
1f20_A_12061f20   A     GOLGLYCEROL W - 1214
1g8k_A_7271g8k   A     HGMERCURY (II) ION N - 731
1g8k_A_7271g8k   A     HGMERCURY (II) ION P - 732
1g8k_A_7271g8k   A     HGMERCURY (II) ION D - 734
1g8k_A_7271g8k   A     HGMERCURY (II) ION C - 735
1g8k_A_7271g8k   A     HGMERCURY (II) ION K - 736
1iz0_A_271iz0   A     MSESELENOMETHIONINE V - 35
1iz0_A_271iz0   A     MSESELENOMETHIONINE G - 36
1iz0_A_271iz0   A     MSESELENOMETHIONINE N - 38
1iz0_A_271iz0   A     MSESELENOMETHIONINE F - 39
1iz0_A_271iz0   A     MSESELENOMETHIONINE A - 40
1iz0_A_271iz0   A     MSESELENOMETHIONINE D - 41
1iz0_A_271iz0   A     MSESELENOMETHIONINE H - 42
1j3b_A_761j3b   A     GOLGLYCEROL Y - 93
1ko3_A_1351ko3   A     ZNZINC ION A - 135
1ko3_A_1351ko3   A     ACTACETATE ION A - 135
1ko3_A_1351ko3   A     ZNZINC ION T - 136
1ko3_A_1351ko3   A     ACTACETATE ION T - 136
1ko3_A_1351ko3   A     ZNZINC ION Y - 137
1ko3_A_1351ko3   A     ACTACETATE ION Y - 137
1ksi_A_2971ksi   A     TPQ5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE F - 298
1ksi_A_2971ksi   A     TPQ5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE D - 300
1kv7_A_3471kv7   A     CUCOPPER (II) ION L - 353
1kv7_A_3471kv7   A     CUCOPPER (II) ION M - 355
1kwg_A_2611kwg   A     MPD2-METHYL-2,4-PENTANEDIOL F - 270
1kwg_A_2611kwg   A     MPD2-METHYL-2,4-PENTANEDIOL L - 273
1lf2_A_2201lf2   A     R373-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE T - 221
1lri_A_811lri   A     CLRCHOLESTEROL L - 82
1lri_A_811lri   A     CLRCHOLESTEROL V - 84
1lri_A_811lri   A     CLRCHOLESTEROL Y - 87
1lri_A_811lri   A     CLRCHOLESTEROL A - 88
1ls6_A_181ls6   A     NPOP-NITROPHENOL I - 21
1ls6_A_181ls6   A     NPOP-NITROPHENOL F - 24
1m3u_A_2101m3u   A     KPLKETOPANTOATE I - 212
1m3u_A_2101m3u   A     KPLKETOPANTOATE L - 213
1m3u_A_2101m3u   A     KPLKETOPANTOATE V - 214
1n9l_A_341n9l   A     FMNFLAVIN MONONUCLEOTIDE L - 34
1n9l_A_341n9l   A     FMNFLAVIN MONONUCLEOTIDE F - 41
1ndy_A_2581ndy   A     FR31-((1R)-1-(HYDROXYMETHYL)-3-(1-NAPHTHYL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE S - 265
1obo_A_10611obo   A     FMNFLAVIN MONONUCLEOTIDE E - 1061
1obo_A_10611obo   A     FMNFLAVIN MONONUCLEOTIDE Q - 1063
1p99_A_2031p99   A     GLYGLYCINE N - 207
1p99_A_2031p99   A     METMETHIONINE N - 207
1p99_A_2031p99   A     GLYGLYCINE N - 208
1p99_A_2031p99   A     METMETHIONINE N - 208
1p99_A_2031p99   A     GLYGLYCINE G - 209
1p99_A_2031p99   A     METMETHIONINE G - 209
1p99_A_2031p99   A     GLYGLYCINE V - 210
1pp7_U_651pp7   U     ZNZINC ION L - 74
1qw2_A_911qw2   A     MSESELENOMETHIONINE E - 91
1qw2_A_911qw2   A     MSESELENOMETHIONINE A - 92
1qw2_A_911qw2   A     MSESELENOMETHIONINE S - 93
1qw2_A_911qw2   A     MSESELENOMETHIONINE Q - 94
1rvk_A_2781rvk   A     MSESELENOMETHIONINE I - 278
1rvk_A_2781rvk   A     MSESELENOMETHIONINE L - 279
1rvk_A_2781rvk   A     MGMAGNESIUM ION R - 280
1rvk_A_2781rvk   A     MSESELENOMETHIONINE T - 281
1rvk_A_2781rvk   A     MSESELENOMETHIONINE V - 283
1rvk_A_2781rvk   A     MSESELENOMETHIONINE N - 284
1uca_A_31uca   A     U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER Q - 9
1uca_A_31uca   A     U2PPHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER V - 14
1vjf_A_1131vjf   A     GOLGLYCEROL V - 113
1vjf_A_1131vjf   A     MSESELENOMETHIONINE R - 114
1vjf_A_1131vjf   A     GOLGLYCEROL R - 114
1vjf_A_1131vjf   A     MSESELENOMETHIONINE F - 115
1vjf_A_1131vjf   A     GOLGLYCEROL F - 115
1vjf_A_1131vjf   A     MSESELENOMETHIONINE V - 116
1vjf_A_1131vjf   A     MSESELENOMETHIONINE L - 117
1vjf_A_1131vjf   A     MSESELENOMETHIONINE D - 118
4nos_A_4334nos   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 434
4nos_A_4334nos   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 439

Clusters included in this Subclass
CLUSTER: EH.0.7
CLUSTER: EH.1.12
CLUSTER: EH.1.26
CLUSTER: EH.2.25
CLUSTER: EH.2.6