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Information on SUBCLASS 1.1.2
Subclass Accession number: 8784
Subclass: 1.1.2 PSSM
Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 45

Average sequence ID (%) : 10.0 +/- 14.0
Average RMSD (Å) : 0.500 +/- 0.175

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 45-90 rho (°): 180-225
Consensus Sequence: XXpXX
(φψ)-conformation: aapaa
Pattern: x[acfilmvwy][afgiklmtv][aegknqrst][adegknqst]xx[acfgilmvy]x
Conservation:-1.147-0.474-0.4330.2512.394-0.110-0.106-0.6260.250
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a2v_A_1241a2v   A127135VIRNDPAVIHHHT-HHHHaaaaxaaaa
1aqw_A_1871aqw   A191199AFLASPEYVHHHHSHHHHaaaaxaaaa
1cpy_*_2711cpy   -277285DYLNQDYVKHHHHSHHHHaaaapaaaa
1cxq_A_1241cxq   A124132SCFTSKSTRHHHHSHHHHaaaaxaaaa
1dqa_A_5991dqa   A607615AWLETSEGFHHHTSHHHHaaaaxaaaa
1dv1_A_4181dv1   A423431RIMNDENFQHHHH-HHHHaaaaxaaaa
1ex4_A_1191ex4   A119127SNFTGATVRHHHH-HHHHaaaapaaaa
1ex9_A_1551ex9   A159167LESLNSEGAHHHHSHHHHaaaaxaaaa
1f0l_A_2061f0l   A219227SLKEHGPIKHHHT-HHHHaaaaxaaaa
1f28_A_881f28   A8896DANGSREYLHHHHSHHHHaaaaxaaaa
1fc4_A_2581fc4   A264272LRQRSRPYLHHHH-HHHHaaaaxaaaa
1fgj_A_2701fgj   A273281AYTMSKHGKHHHHSHHHHaaaaxaaaa
1fs7_A_2791fs7   A282290LYKTGIHGQHHHHSHHHHaaaaxaaaa
1g4i_A_401g4i   A5462QAKKLDSCKHHHH-HHHHaaaaxaaaa
1gpu_A_1571gpu   A158166GCLQEGISSHHHHSHHHHaaaaxaaaa
1gu6_A_2661gu6   A269277TWTAGIHGKHHHHSHHHHaaaaxaaaa
1ho8_A_1581ho8   A163171KLLKNNNLIHHHH-HHHHaaaaxaaaa
1hzt_A_1601hzt   A164172MQATNREARHHHHSHHHHaaaaxaaaa
1iat_A_21iat   A210ALTRDPQFQHHHH-HHHHaaaaxaaaa
1ire_A_1241ire   A124132NWFKEPQYRHHHHSHHHHaaaaxaaaa
1itk_A_3701itk   A374382ALKRDPDYRHHHHSHHHHaaaaxaaaa
1jdr_A_2331jdr   A237245SLIQDPKYLHHHHSHHHHaaaaxaaaa
1k3p_A_3381k3p   A345353IALNDPYFIHHHH-HHHHaaaaxaaaa
1k3x_A_1151k3x   A115123QLTTHPFLQHHHHSHHHHaaaapaaaa
1kbl_A_5641kbl   A564572HMFFEADRIHHHHSHHHHaaaapaaaa
1llf_A_731llf   A8088LVMQSKVFQHHHHSHHHHaaaaxaaaa
1mvl_A_1431mvl   A144152LMWNNPFTEHHHHSHHHHaaaaxaaaa
1mxr_A_1331mxr   A139147DIVTNEQIQHHHH-HHHHaaaaxaaaa
1n45_A_221n45   A2735QAENAEFMRHHHHSHHHHaaaaxaaaa
1nd6_A_1301nd6   A138146ETLKSEEFQHHHH-HHHHaaaaxaaaa
1nm8_A_5151nm8   A515523DIFMDTSYAHHHHSHHHHaaaaxaaaa
1ogi_A_1591ogi   A167175WRMFKDAERHHHH-HHHHaaaaxaaaa
1omw_A_1601omw   A164172KFIESDKFTHHHTSHHHHaaaabaaaa
1p5h_A_3531p5h   A355363ELAHDPSLQHHHH-HHHHaaaaxaaaa
1q7e_A_3451q7e   A345353EISLDPSLRHHHH-HHHHUaaaxaaaa
1qdb_A_2841qdb   A287295FWKSGIHGQHHHHSHHHHaaaaxaaaa
1qdl_A_2501qdl   A259267ELMNSEKDKHHHT-HHHHaaaaxaaaa
1qgd_A_1551qgd   A156164GCMMEGISHHHHHSHHHHaaaaxaaaa
1qgu_B_351qgu   B4351AWTTTAEYEHHHTSHHHHaaaaxaaaa
1qsa_A_3781qsa   A378386ALTQGPEMAHHHHSHHHHaaaaxaaaa
1rpa_*_1301rpa   -138146ETLKSEEFLHHHHSHHHHaaaabaaaa
2ahj_A_1252ahj   A125133TWYKSFEYRHHHHSHHHHaaaaxaaaa
2cbl_A_1062cbl   A108116TLGENEYFRHHHH-HHHHaaaapaaaa
3gtu_B_1953gtu   B199207AYLQSDQFCHHHH-HHHHaaaaxaaaa
3thi_A_2833thi   A291299NVMASADTVHHHHSHHHHaaaaxaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aqw_A_1871aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID K - 188
1aqw_A_1871aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID F - 192
1aqw_A_1871aqw   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID E - 197
1ex9_A_1551ex9   A     OCPOCTYL-PHOSPHINIC ACID 1,2-BIS-OCTYLCARBAMOYLOXY-ETHYL ESTER L - 159
1ex9_A_1551ex9   A     OCPOCTYL-PHOSPHINIC ACID 1,2-BIS-OCTYLCARBAMOYLOXY-ETHYL ESTER L - 162
1f28_A_881f28   A     F89S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN -9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID N - 90
1fc4_A_2581fc4   A     AKB2-AMINO-3-KETOBUTYRIC ACID L - 272
1fc4_A_2581fc4   A     MSESELENOMETHIONINE F - 273
1fc4_A_2581fc4   A     AKB2-AMINO-3-KETOBUTYRIC ACID F - 273
1fc4_A_2581fc4   A     PLPPYRIDOXAL-5'-PHOSPHATE F - 273
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 270
1fgj_A_2701fgj   A     HECHEME C N - 270
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE W - 271
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 272
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE Y - 274
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE T - 275
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE K - 278
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 279
1fgj_A_2701fgj   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 282
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE D - 279
1fs7_A_2791fs7   A     CACALCIUM ION D - 279
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE W - 280
1fs7_A_2791fs7   A     CACALCIUM ION W - 280
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 281
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE Y - 283
1fs7_A_2791fs7   A     CACALCIUM ION Y - 283
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE K - 284
1fs7_A_2791fs7   A     ACTACETATE ION G - 286
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE I - 287
1fs7_A_2791fs7   A     CACALCIUM ION I - 287
1fs7_A_2791fs7   A     ACTACETATE ION I - 287
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 288
1fs7_A_2791fs7   A     CACALCIUM ION H - 288
1fs7_A_2791fs7   A     HEMPROTOPORPHYRIN IX CONTAINING FE G - 289
1g4i_A_401g4i   A     CACALCIUM ION C - 45
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL C - 45
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL H - 48
1g4i_A_401g4i   A     CACALCIUM ION D - 49
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL D - 49
1g4i_A_401g4i   A     MPD2-METHYL-2,4-PENTANEDIOL Y - 52
1gpu_A_1571gpu   A     CACALCIUM ION D - 157
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE D - 157
1gpu_A_1571gpu   A     CACALCIUM ION G - 158
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE G - 158
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE C - 159
1gpu_A_1571gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE E - 162
1gu6_A_2661gu6   A     CACALCIUM ION E - 266
1gu6_A_2661gu6   A     HECHEME C E - 266
1gu6_A_2661gu6   A     CACALCIUM ION Y - 267
1gu6_A_2661gu6   A     HECHEME C Y - 267
1gu6_A_2661gu6   A     GOLGLYCEROL E - 268
1gu6_A_2661gu6   A     GOLGLYCEROL T - 269
1gu6_A_2661gu6   A     CACALCIUM ION W - 270
1gu6_A_2661gu6   A     HECHEME C W - 270
1gu6_A_2661gu6   A     GOLGLYCEROL T - 271
1gu6_A_2661gu6   A     GOLGLYCEROL A - 272
1gu6_A_2661gu6   A     CACALCIUM ION I - 274
1gu6_A_2661gu6   A     HECHEME C I - 274
1gu6_A_2661gu6   A     CACALCIUM ION H - 275
1gu6_A_2661gu6   A     HECHEME C H - 275
1ire_A_1241ire   A     CSD3-SULFINOALANINE F - 126
1ire_A_1241ire   A     CEAS-HYDROXY-CYSTEINE F - 126
1ire_A_1241ire   A     CSD3-SULFINOALANINE K - 127
1ire_A_1241ire   A     CSD3-SULFINOALANINE E - 128
1ire_A_1241ire   A     CSD3-SULFINOALANINE R - 132
1itk_A_3701itk   A     HEMPROTOPORPHYRIN IX CONTAINING FE T - 371
1jdr_A_2331jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE T - 234
1jdr_A_2331jdr   A     HEMPROTOPORPHYRIN IX CONTAINING FE D - 235
1k3x_A_1151k3x   A     GOLGLYCEROL T - 117
1k3x_A_1151k3x   A     GOLGLYCEROL T - 118
1k3x_A_1151k3x   A     GOLGLYCEROL Q - 123
1k3x_A_1151k3x   A     GOLGLYCEROL R - 124
1mvl_A_1431mvl   A     FMNFLAVIN MONONUCLEOTIDE M - 145
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 25
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 28
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 29
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 30
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 34
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE R - 35
1n45_A_221n45   A     HEMPROTOPORPHYRIN IX CONTAINING FE Q - 38
1ogi_A_1591ogi   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 160
1ogi_A_1591ogi   A     FADFLAVIN-ADENINE DINUCLEOTIDE P - 161
1q7e_A_3451q7e   A     MSESELENOMETHIONINE E - 345
1q7e_A_3451q7e   A     MSESELENOMETHIONINE I - 346
1q7e_A_3451q7e   A     MSESELENOMETHIONINE S - 347
1q7e_A_3451q7e   A     MSESELENOMETHIONINE L - 348
1qdb_A_2841qdb   A     CACALCIUM ION G - 284
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE G - 284
1qdb_A_2841qdb   A     CACALCIUM ION F - 285
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 285
1qdb_A_2841qdb   A     CACALCIUM ION W - 288
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE W - 288
1qdb_A_2841qdb   A     CACALCIUM ION I - 292
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE I - 292
1qdb_A_2841qdb   A     CACALCIUM ION H - 293
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 293
1qdb_A_2841qdb   A     HEMPROTOPORPHYRIN IX CONTAINING FE G - 294
1qgd_A_1551qgd   A     CACALCIUM ION D - 155
1qgd_A_1551qgd   A     TPPTHIAMINE DIPHOSPHATE D - 155
1qgd_A_1551qgd   A     CACALCIUM ION G - 156
1qgd_A_1551qgd   A     TPPTHIAMINE DIPHOSPHATE G - 156
1qgd_A_1551qgd   A     TPPTHIAMINE DIPHOSPHATE C - 157
1qgd_A_1551qgd   A     TPPTHIAMINE DIPHOSPHATE M - 159
1qgd_A_1551qgd   A     TPPTHIAMINE DIPHOSPHATE E - 160
1qgu_B_351qgu   B     MO6MAGNESIUM ION, 6 WATERS COORDINATED V - 38
1qgu_B_351qgu   B     EDO1,2-ETHANEDIOL E - 51
1qgu_B_351qgu   B     EDO1,2-ETHANEDIOL A - 52
1qgu_B_351qgu   B     EDO1,2-ETHANEDIOL N - 54
1qsa_A_3781qsa   A     ACTACETATE ION L - 391
2ahj_A_1252ahj   A     CSD3-SULFINOALANINE Y - 127
2ahj_A_1252ahj   A     CEAS-HYDROXY-CYSTEINE Y - 127
2ahj_A_1252ahj   A     CSD3-SULFINOALANINE K - 128
2ahj_A_1252ahj   A     CSD3-SULFINOALANINE R - 133
2cbl_A_1062cbl   A     CACALCIUM ION N - 121
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gpu_A_1571gpu   A AC1CA BINDING SITE FOR CHAIN AD - 157
1gpu_A_1571gpu   A AC2THD BINDING SITE FOR CHAIN AE - 162
1gu6_A_2661gu6   A HA4HEC BINDING SITE FOR CHAIN AE - 266
1gu6_A_2661gu6   A HA4HEC BINDING SITE FOR CHAIN AW - 270
1gu6_A_2661gu6   A HA5HEC BINDING SITE FOR CHAIN AI - 274
1gu6_A_2661gu6   A HA4HEC BINDING SITE FOR CHAIN AH - 275
1ogi_A_1591ogi   A AC1FAD BINDING SITE FOR CHAIN AT - 160
1qgd_A_1551qgd   A TPACOFACTOR BINDINGD - 155
1qgd_A_1551qgd   A TPACOFACTOR BINDINGG - 156

Clusters included in this Subclass
CLUSTER: HH.0.15
CLUSTER: HH.0.7
CLUSTER: HH.1.19
CLUSTER: HH.1.23
CLUSTER: HH.1.44
CLUSTER: HH.2.68
CLUSTER: HH.2.74
CLUSTER: HH.2.9