Logo
Information on SUBCLASS 4.1.1
Subclass Accession number: 266
Subclass: 4.1.1 PSSM
Type: HE alpha-beta
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 42

Average sequence ID (%) : 16.3 +/- 16.4
Average RMSD (Å) : 0.655 +/- 0.213

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: pXXPphXh
(φψ)-conformation: aabaapbb
Pattern: x[adeknqrs][adegkqrs][acfilvw][aegknqrt][ADEGKQRST]xx[ekps][degknqrs][acfgilmvy]x[acfgilmpvy]
Conservation:-0.592-0.032-0.4930.497-0.4890.464-0.680-0.9932.8640.350-0.304-0.8710.279
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1bpy_A_1521bpy   A163175LNEVKKVDSEYIAHHHHHHH-TT-EEaaaaaaabaaxbb
1bwv_S_801bwv   S8799INACRKARSNFYIHHHHHHH-TTSEEaaaaaaabaabxb
1cex_*_921cex   -102114FQQANTKCPDATLHHHHHHH-TT-EEaaaaaaabaaxxx
1chm_A_1301chm   A133145RDKLAARYPDAELHHHHHHH-TT-EEaaaaaaabaabxb
1cl1_A_1661cl1   A170182VAAVRSVVPDAIIHHHHHHH-TT-EEaaaaaaabaaxbb
1d3v_A_1041d3v   A108120ISGHARVHPDLCVHHHHHHH-TT-EEaaaaaaabaaxbb
1dlj_A_951dlj   A101113IKEVLSVNSHATLHHHHHHH-SS-EEaaaaaaabaaxxx
1dqn_A_1321dqn   A134146IFSIQEQIKHAKIHHHHHHHSTT-EEaaaaaaabaaxbb
1eg5_A_1581eg5   A162174TRIVKKKNKETLVHHHHHHH-TT-EEaaaaaaabaaxxb
1eu8_A_151eu8   A2537IAEFEKKYPGVTVHHHHHHHSTT-EEaaaaaaabaabbb
1ewq_A_151ewq   A2032YVELRDQYPDYLLHHHHHHH-TTSEEaaaaaaabaabxx
1fp1_D_2221fp1   D224236LELIISKYPLIKGHHHHHHH-TT-EEaaaaaaabaaxxx
1g2o_A_1621g2o   A165177RELARQSDPQLAEHHHHHHH-TT-EEaaaaaaabaapxb
1g66_A_571g66   A7284VNSFNSQCPSTKIHHHHHHHSTT-EEaaaaaaabaaxxb
1gk8_I_861gk8   I93105IVACTKAFPDAYVHHHHHHH-TTSEEaaaaaaabaaxxb
1gnu_A_111gnu   A1830GEKIRKKYPDRVPHHHHHHH-TTEEEaaaaaaabaabbw
1gt9_1_761gt9   18395IEVAGALAPGAKIHHHHHHHSTTSEEaaaaaaabaaxxb
1hwl_A_6571hwl   A668680LSKLHEYFPEMQIHHHHHHH-TT-EEaaaaaaabaaxbx
1iug_A_1401iug   A144156ARAFKEKNPEGLVHHHHHHH-TT-EEaaaaaaabaaxbb
1j0h_A_3351j0h   A342354RQEVKALKPDVYIHHHHHHH-TT-EEaaaaaaabaaxxb
1ji1_A_3711ji1   A381393RNAVKGVNSNAAIHHHHHHH-TT-EEaaaaaaabaaxxb
1ji2_A_3321ji2   A339351RRLVKSLNPDALIHHHHHHH-TT-EEaaaaaaabaaxxb
1jih_A_771jih   A7789IQEALKKCSNLIPHHHHHHH-TT-EEaaaaaaabaaxbw
1jlr_A_1991jlr   A202214IERVFKEYPKVRMHHHHHHH-TT-EEaaaaaaabaaxbb
1jn3_A_1521jn3   A163175LNEVKKLDPEYIAHHHHHHH-TT-EEaaaaaaabaaxbb
1jx4_A_611jx4   A6173IVEAKKILPNAVYHHHHHHH-TTSEEaaaaaaabaaxxb
1lhp_A_881lhp   A98110VQELKQQNPRLVYHHHHHHH-TT-EEaaaaaaabaaxbb
1m6y_A_371m6y   A3951SRAILEHCPGCRIHHHHHHH-TT-EEaaaaaaabaaxbb
1nul_A_971nul   A97109AVAIREMYPKAHFHHHHHHH-TTSEEaaaaaaabaaxxx
1nvm_A_691nvm   A7385IEAVAGEISHAQIHHHHHTT-SSSEEaaaaaaabNaxxx
1nvm_B_811nvm   B88100EALLRQAKPGIRLHHHHHHH-TT-EEaaaaaaabaaxxb
1o5o_A_1641o5o   A167179VEAVEKKYEDVKIHHHHHHH-TT-EEaaaaaaabaaxxb
1o5o_A_811o5o   A8597ADGILELLPNASVHHHHHHHSTT-EEaaaaaaabaaxxb
1pda_*_141pda   -2436KDKLMASHPGLVVHHHHHHH-TT-EEaaaaaaabaaxbb
1pq4_A_1131pq4   A113125LEKLKAANANMKLHHHHHHH-SSSEEaaaaaaabaaxxx
1qgo_A_151qgo   A2638ERDLAASCPDRDLHHHHHHT-TTSEEaaaaaaabaabxx
1rzt_A_3891rzt   A400412QKAAQAFNSGLLCHHHHHTT-TT-EEaaaaaaabaapbb
1ufa_A_3181ufa   A336348LERLAGRHPEGVIHHHHHHH-TT-EEaaaaaaabaaxbx
1v4v_A_2141v4v   A221233LKRVAEAFPHLTFHHHHHHH-TTSEEaaaaaaabaabbx
1vi9_A_871vi9   A97109VRQVKAANPQAKYHHHHHHH-TT-EEaaaaaaabaaxbb
1ypc_I_321ypc   I3648KKVILQDKPEAQIHHHHHHH-TT-EEaaaaaaabaaxxb
3thi_A_223thi   A3042LDQWQRQEPGVKLHHHHHHH-TTSEEaaaaaaabaabxb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1cl1_A_1661cl1   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) D - 185
1d3v_A_1041d3v   A     MNMANGANESE (II) ION W - 122
1d3v_A_1041d3v   A     ABH2(S)-AMINO-6-BORONOHEXANOIC ACID W - 122
1d3v_A_1041d3v   A     MNMANGANESE (II) ION V - 123
1dlj_A_951dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE H - 96
1dlj_A_951dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE T - 99
1dlj_A_951dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE V - 100
1dlj_A_951dlj   A     NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE E - 103
1dqn_A_1321dqn   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER H - 132
1dqn_A_1321dqn   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER T - 133
1dqn_A_1321dqn   A     POPPYROPHOSPHATE 2- T - 133
1dqn_A_1321dqn   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER I - 134
1eg5_A_1581eg5   A     MSESELENOMETHIONINE V - 158
1eg5_A_1581eg5   A     MSESELENOMETHIONINE H - 175
1eg5_A_1581eg5   A     MSESELENOMETHIONINE V - 176
1eg5_A_1581eg5   A     MSESELENOMETHIONINE D - 177
1eg5_A_1581eg5   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 177
1eu8_A_151eu8   A     TRETREHALOSE E - 17
1ewq_A_151ewq   A     MSESELENOMETHIONINE V - 21
1ewq_A_151ewq   A     MSESELENOMETHIONINE R - 24
1ewq_A_151ewq   A     MSESELENOMETHIONINE D - 25
1fp1_D_2221fp1   D     SAHS-ADENOSYL-L-HOMOCYSTEINE N - 223
1fp1_D_2221fp1   D     HCC2',4,4'-TRIHYDROXYCHALCONE N - 223
1fp1_D_2221fp1   D     SAHS-ADENOSYL-L-HOMOCYSTEINE F - 239
1fp1_D_2221fp1   D     SAHS-ADENOSYL-L-HOMOCYSTEINE D - 240
1g2o_A_1621g2o   A     PO4PHOSPHATE ION Y - 180
1g2o_A_1621g2o   A     IMH1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL Y - 180
1g66_A_571g66   A     GOLGLYCEROL Y - 57
1g66_A_571g66   A     GOLGLYCEROL S - 70
1g66_A_571g66   A     GOLGLYCEROL N - 73
1g66_A_571g66   A     GOLGLYCEROL S - 74
1g66_A_571g66   A     GOLGLYCEROL F - 75
1g66_A_571g66   A     GOLGLYCEROL S - 77
1g66_A_571g66   A     GOLGLYCEROL Q - 78
1hwl_A_6571hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID M - 657
1hwl_A_6571hwl   A     FBI7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID S - 661
1iug_A_1401iug   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) D - 159
1jx4_A_611jx4   A     MSESELENOMETHIONINE L - 74
1jx4_A_611jx4   A     CACALCIUM ION L - 74
1m6y_A_371m6y   A     SAHS-ADENOSYL-L-HOMOCYSTEINE G - 37
1m6y_A_371m6y   A     MSESELENOMETHIONINE H - 38
1m6y_A_371m6y   A     SAHS-ADENOSYL-L-HOMOCYSTEINE H - 38
1m6y_A_371m6y   A     SAHS-ADENOSYL-L-HOMOCYSTEINE S - 39
1m6y_A_371m6y   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 54
1m6y_A_371m6y   A     MSESELENOMETHIONINE D - 55
1m6y_A_371m6y   A     SAHS-ADENOSYL-L-HOMOCYSTEINE D - 55
1nvm_B_811nvm   B     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 81
1nvm_B_811nvm   B     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 83
1nvm_B_811nvm   B     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 87
1nvm_A_691nvm   A     OXLOXALATE ION L - 88
1nvm_B_811nvm   B     MPD2-METHYL-2,4-PENTANEDIOL A - 89
1nvm_B_811nvm   B     MPD2-METHYL-2,4-PENTANEDIOL L - 90
1nvm_B_811nvm   B     MPD2-METHYL-2,4-PENTANEDIOL L - 91
1nvm_B_811nvm   B     MPD2-METHYL-2,4-PENTANEDIOL Q - 93
1nvm_B_811nvm   B     MPD2-METHYL-2,4-PENTANEDIOL A - 94
1pda_*_141pda   *     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID P - 14
1pda_*_141pda   *     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID L - 15
1pda_*_141pda   *     DPM3-{2-[4-(2-CARBOXY-ETHYL)-3-CARBOXYMETHYL-5H-PYRROL-2-YLMETHYL]-4-CARBOXYMETHYL-5-METHYL-2H-PYRROL-3-YL}-PROPIONIC ACID A - 16
1ufa_A_3181ufa   A     MSESELENOMETHIONINE H - 343
1ufa_A_3181ufa   A     MSESELENOMETHIONINE P - 344
1ufa_A_3181ufa   A     MSESELENOMETHIONINE E - 345
1ufa_A_3181ufa   A     MSESELENOMETHIONINE G - 346
1ufa_A_3181ufa   A     MSESELENOMETHIONINE L - 349
1ufa_A_3181ufa   A     MSESELENOMETHIONINE P - 351
1v4v_A_2141v4v   A     MSESELENOMETHIONINE L - 214
1v4v_A_2141v4v   A     MSESELENOMETHIONINE L - 217
1v4v_A_2141v4v   A     MSESELENOMETHIONINE A - 218
1v4v_A_2141v4v   A     MSESELENOMETHIONINE L - 221
1v4v_A_2141v4v   A     MSESELENOMETHIONINE Y - 235
1v4v_A_2141v4v   A     MSESELENOMETHIONINE P - 236
1vi9_A_871vi9   A     MSESELENOMETHIONINE Q - 89

Clusters included in this Subclass
CLUSTER: HE.3.12
CLUSTER: HE.3.72
CLUSTER: HE.4.16
CLUSTER: HE.5.136
CLUSTER: HE.5.27
CLUSTER: HE.5.8
CLUSTER: HE.6.134