Information on SUBCLASS 2.1.2 |
Subclass Accession number: 7124
Subclass: 2.1.2 Type: EH beta-alpha DB: ArchDB-EC Image coordinates: Consensus coordinates: |
Number of loops: 104 Average sequence ID (%) : 10.3 +/- 13.7 Average RMSD (Å) : 0.552 +/- 0.202 Consensus geometry
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Consensus Sequence: | XXXpXX |
(φψ)-conformation: | bbabaa |
Pattern: | x | x | x | x | [dehnrsty] | x | x | x | [acfgilmvwy] |
Conservation: | -0.202 | -0.809 | 0.282 | -0.701 | 2.290 | -0.822 | -0.714 | 0.144 | 0.532 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a53_*_157 | 1a53 | - | 158 | 166 | IEINDENDL | EEE-SHHHH | bxbabaaaa |
1air_*_19 | 1air | - | 21 | 29 | KTATSMQDI | EEESSHHHH | bbbabaaaa |
1aq0_A_201 | 1aq0 | A | 201 | 209 | YGYQNLFDT | EEE-SHHHH | xbbabaaaa |
1ayl_*_133 | 1ayl | - | 137 | 145 | FITEVAWQA | EEES-HHHH | xbbabaaaa |
1b24_A_126 | 1b24 | A | 127 | 135 | IWNKNKALL | EEES-HHHH | bbbabaaaa |
1b93_A_116 | 1b93 | A | 116 | 123 | .VATNVATA | .EESSHHHH | .bbabaaaa |
1bfd_*_493 | 1bfd | - | 495 | 503 | LKADNLEQL | EEESSHHHH | bbbabaaaa |
1bg6_*_64 | 1bg6 | - | 64 | 72 | LLTSDIGLA | EEES-HHHH | bbbabaaaa |
1bn8_A_32 | 1bn8 | A | 33 | 41 | YTVSNRNQL | EEE-SHHHH | bbbabaaaa |
1c30_A_146 | 1c30 | A | 147 | 155 | GIAHTMEEA | EEESSHHHH | bxbabaaaa |
1c30_A_180 | 1c30 | A | 180 | 188 | GIAYNREEF | EEESSHHHH | ebxabaaaa |
1c7g_A_265 | 1c7g | A | 267 | 275 | LCMNDEEMF | EEES-HHHH | bbbaxaaaa |
1cp2_A_143 | 1cp2 | A | 147 | 155 | VASGEMMAL | EE-SSHHHH | xbbabaaaa |
1cs1_A_209 | 1cs1 | A | 211 | 219 | VIAKDPDVV | EEESSHHHH | bbbaxaaaa |
1d7k_B_86 | 1d7k | B | 87 | 95 | FDCASKTEI | EEE-SHHHH | bxbabaaaa |
1dbg_A_27 | 1dbg | A | 27 | 34 | .VVASNETL | .EE-SHHHH | .xbabaaaa |
1dfa_A_336 | 1dfa | A | 339 | 347 | IKTIHTSVR | EEES-HHHH | xbbaxaaaa |
1dii_A_398 | 1dii | A | 398 | 406 | VSEARGSEC | EEES-HHHH | bbxxbaaaa |
1duv_G_211 | 1duv | G | 213 | 221 | TLTEDVAKG | EEES-HHHH | bbbaxaaaa |
1e6y_A_1176 | 1e6y | A | 1179 | 1187 | VFTGDDALA | EEES-HHHH | bbbaxaaaa |
1ed8_A_235 | 1ed8 | A | 235 | 243 | QLVSDAASL | EEE-SHHHH | xbbabaaaa |
1eep_A_196 | 1eep | A | 200 | 208 | GNIVTKEAA | EEE-SHHHH | Oxbabaaaa |
1eua_A_111 | 1eua | A | 113 | 121 | PGISTVSEL | EEESSHHHH | xxbabaaaa |
1euc_B_22 | 1euc | B | 23 | 31 | FVADTANEA | EEESSHHHH | bbbabaaaa |
1ew2_A_244 | 1ew2 | A | 245 | 253 | RYVWNRTEL | EEE-SHHHH | bbbabaaaa |
1ex7_A_164 | 1ex7 | A | 166 | 174 | IVNDDLDKA | EE-SSHHHH | bxxabaaaa |
1ezi_A_47 | 1ezi | A | 50 | 58 | VSTDGGLIA | EEES-HHHH | bbbabaaaa |
1f3t_A_86 | 1f3t | A | 87 | 95 | FDCASNTEI | EEE-SHHHH | bxbabaaaa |
1fmt_A_5 | 1fmt | A | 8 | 16 | FAGTPDFAA | EEE-SHHHH | bbbaxaaaa |
1fp6_A_146 | 1fp6 | A | 150 | 158 | VCSGEMMAM | EE-SSHHHH | xbbabaaaa |
1ghs_A_201 | 1ghs | A | 201 | 208 | .TYTSLFDA | .EE--HHHH | .bbabaaaa |
1gsa_*_138 | 1gsa | - | 139 | 147 | LVTRNKAQL | EEES-HHHH | bbbabaaaa |
1gso_A_155 | 1gso | A | 156 | 164 | IVAMTLEEA | EEESSHHHH | bxbabaaaa |
1h05_A_46 | 1h05 | A | 50 | 58 | RQSDSEAQL | EE-S-HHHH | bbbaxaaaa |
1hkv_A_134 | 1hkv | A | 134 | 142 | IVVDSMTEI | EEE-SHHHH | bxxabaaaa |
1hkv_A_89 | 1hkv | A | 90 | 98 | LDVCTGGEL | EEE-SHHHH | bbbabaaaa |
1i1q_A_67 | 1i1q | A | 70 | 78 | IQALSDNGA | EEESSHHHH | bbxabaaaa |
1i4n_A_153 | 1i4n | A | 156 | 164 | VEVHSREDL | EEE-SHHHH | xxbabaaaa |
1i8t_A_58 | 1i8t | A | 58 | 66 | FHTNDKYIW | EEES-HHHH | xbbaxaaaa |
1iay_A_287 | 1iay | A | 290 | 298 | IYSFNDDVV | EEES-HHHH | bbxabaaaa |
1iho_A_2 | 1iho | A | 2 | 10 | LIIETLPLL | EEE-SHHHH | xbbabaaaa |
1ihp_*_134 | 1ihp | - | 136 | 144 | RSSGSSRVI | EEES-HHHH | bbxxbaaaa |
1ii2_A_106 | 1ii2 | A | 110 | 118 | VFTTRPYHA | EEESSHHHH | bbbaxaaaa |
1jl1_A_64 | 1jl1 | A | 67 | 75 | LSTDSQYVR | EEE--HHHH | bbbaxaaaa |
1jr1_A_298 | 1jr1 | A | 302 | 310 | GNVVTAAQA | EEE-SHHHH | ppbabaaaa |
1jr2_A_58 | 1jr2 | A | 59 | 67 | LIFTSPRAV | EEE--HHHH | bbbabaaaa |
1jta_A_35 | 1jta | A | 36 | 44 | YIVTNISEF | EEE-SHHHH | bbbabaaaa |
1jys_A_2 | 1jys | A | 5 | 13 | IIGAMEEEV | EEES-HHHH | bbbaxaaaa |
1kbl_A_402 | 1kbl | A | 406 | 414 | KVYFTADEA | EEESSHHHH | xxbabaaaa |
1khb_A_155 | 1khb | A | 159 | 167 | ELTDSPYVV | EEES-HHHH | bxbabaaaa |
1khh_A_82 | 1khh | A | 87 | 95 | IIECNDGVF | EEE--HHHH | bxbaxaaaa |
1kjq_A_132 | 1kjq | A | 133 | 141 | RFADSESLF | EEESSHHHH | bxbabaaaa |
1knw_A_119 | 1knw | A | 119 | 127 | VNAGSVDML | EEESSHHHH | bxxabaaaa |
1knw_A_71 | 1knw | A | 72 | 80 | VDSVSLGEI | EEE-SHHHH | bbbabaaaa |
1kol_A_212 | 1kol | A | 215 | 223 | VGDLNPARL | EEES-HHHH | bbbaxaaaa |
1kpg_A_90 | 1kpg | A | 92 | 100 | GLTLSKNQA | EEES-HHHH | bbbaxaaaa |
1kpi_A_97 | 1kpi | A | 100 | 108 | GLTLSENQY | EEES-HHHH | bbbaxaaaa |
1kwm_A_11 | 1kwm | A | 15 | 23 | VNVEDENHI | EEE-SHHHH | bxbabaaaa |
1l3i_A_124 | 1l3i | A | 132 | 140 | VTAILLETK | EEE-SHHHH | bxbaxaaaa |
1l6w_A_106 | 1l6w | A | 109 | 117 | TAVYGAAQG | EEE-SHHHH | blxabaaaa |
1li4_A_152 | 1li4 | A | 153 | 161 | ISEETTTGV | EEE-SHHHH | bbbabaaaa |
1lk5_A_52 | 1lk5 | A | 53 | 61 | GVPTSYQAK | EEESSHHHH | bbxabaaaa |
1lk9_A_261 | 1lk9 | A | 263 | 271 | ALIKDESVY | EEES-HHHH | bxbaxaaaa |
1ll2_A_4 | 1ll2 | A | 8 | 16 | TLTTNDAYA | EEESSHHHH | bbbabaaaa |
1lvg_A_167 | 1lvg | A | 169 | 177 | IINDDLDKA | EE-SSHHHH | bxxaxaaaa |
1m6y_A_233 | 1m6y | A | 241 | 249 | VISFHSLED | EEESSHHHH | bbbabaaaa |
1m7y_A_282 | 1m7y | A | 285 | 293 | IYSNDDMVV | EEES-HHHH | bbbaxaaaa |
1me8_A_287 | 1me8 | A | 290 | 298 | GNIVDGEGF | EEE-SHHHH | ewbabaaaa |
1mu2_A_491 | 1mu2 | A | 494 | 502 | IIVDSQYVM | EEES-HHHH | bbbabaaaa |
1mu2_A_511 | 1mu2 | A | 511 | 518 | .ESESKIVN | .EES-HHHH | .bbaxaaaa |
1mv8_A_174 | 1mv8 | A | 176 | 184 | IGELDKQTG | EEESSHHHH | bxbaxaaaa |
1mv8_A_64 | 1mv8 | A | 65 | 73 | SGTTDFKKA | EEES-HHHH | bbbaxaaaa |
1mxs_A_126 | 1mxs | A | 126 | 133 | .GISTPSEI | .EE-SHHHH | .xbabaaaa |
1n3l_A_287 | 1n3l | A | 287 | 295 | KTYTAYVDL | EEESSHHHH | bbxabaaaa |
1n8p_A_214 | 1n8p | A | 216 | 224 | LATNNKPLY | EEES-HHHH | bbbaxaaaa |
1nd6_A_70 | 1nd6 | A | 73 | 81 | RSTDVDRTL | EEES-HHHH | bbxxbaaaa |
1ng4_A_95 | 1ng4 | A | 97 | 105 | KLAFSEEDV | EEESSHHHH | xxbabaaaa |
1noy_A_183 | 1noy | A | 186 | 194 | MPFDNERDM | EEES-HHHH | bxbabaaaa |
1nsj_*_99 | 1nsj | - | 104 | 112 | VGVSNERDM | EEESSHHHH | bxbabaaaa |
1nw3_A_181 | 1nw3 | A | 184 | 192 | GVEKADIPA | EEE-SHHHH | bbbaxaaaa |
1nwa_A_94 | 1nwa | A | 96 | 104 | IFYFDEQQK | EEESSHHHH | bbxabaaaa |
1nxu_A_205 | 1nxu | A | 205 | 212 | .LTKEPGVI | .EE--HHHH | .xbaxaaaa |
1o08_A_1165 | 1o08 | A | 1167 | 1175 | GLEDSQAGI | EEESSHHHH | bbbabaaaa |
1obb_A_64 | 1obb | A | 66 | 74 | EKTMNLDDV | EEES-HHHH | bbbabaaaa |
1onr_A_153 | 1onr | A | 156 | 164 | TLLFSFAQA | EEE-SHHHH | blxabaaaa |
1oql_A_108 | 1oql | A | 110 | 118 | PFNGSYPDL | EEESSHHHH | abxaxaaaa |
1or8_A_95 | 1or8 | A | 98 | 106 | GIECSSISD | EEE-STHHH | bbbaxaaaa |
1oth_A_244 | 1oth | A | 245 | 253 | LLTNDPLEA | EEES-HHHH | bbbabaaaa |
1pii_*_159 | 1pii | - | 162 | 170 | TEVSNEEEQ | EEE-SHHHH | xxbabaaaa |
1prz_A_148 | 1prz | A | 148 | 155 | .VAKTVPAQ | .EESSHHHH | .bxabaaaa |
1qap_A_211 | 1qap | A | 213 | 221 | VEVENLDEL | EEESSHHHH | bxbabaaaa |
1qfx_A_147 | 1qfx | A | 150 | 158 | FSSGYGRVI | EEESBHHHH | bbxxbaaaa |
1qq5_A_167 | 1qq5 | A | 169 | 177 | FVSSNGFDV | EEES-HHHH | xbbaxaaaa |
1srr_A_29 | 1srr | A | 31 | 39 | FQAANGLQA | EEESSHHHH | bbbabaaaa |
1un8_A_104 | 1un8 | A | 107 | 115 | IVKNYTGDR | EEES-HHHH | bbxxbaaaa |
1uxy_*_17 | 1uxy | - | 21 | 29 | VCAEDEQQL | EEESSHHHH | bxxabaaaa |
1vgv_A_3 | 1vgv | A | 5 | 13 | TVFGTRPEA | EEE-SHHHH | bbbaxaaaa |
1xva_A_80 | 1xva | A | 83 | 91 | SVDASDKML | EEES-HHHH | bbbaxaaaa |
1zpd_A_508 | 1zpd | A | 510 | 518 | LKAKTGGEL | EEESBHHHH | bbbabaaaa |
1zrn_*_171 | 1zrn | - | 173 | 181 | FVASNAWDA | EEES-HHHH | xbbaxaaaa |
2dpm_A_57 | 2dpm | A | 60 | 68 | INDFNAELI | EEES-HHHH | bbbaxaaaa |
2scu_B_22 | 2scu | B | 23 | 31 | YACTTPREA | EEESSHHHH | bxbabaaaa |
2scu_B_60 | 2scu | B | 61 | 69 | KVVNSKEDI | EEESSHHHH | bbbabaaaa |
2tps_A_126 | 2tps | A | 129 | 137 | VSAHTMSEV | EEE-SHHHH | bxbabaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1h05_A_46 | 1h05 | A | SO3SO4 BINDING SITE FOR CHAIN A | R - 50 |
1h05_A_46 | 1h05 | A | SO2SO4 BINDING SITE FOR CHAIN A | S - 54 |
1h05_A_46 | 1h05 | A | SO3SO4 BINDING SITE FOR CHAIN A | W - 61 |
1h05_A_46 | 1h05 | A | SO3SO4 BINDING SITE FOR CHAIN A | Q - 64 |
2tps_A_126 | 2tps | A | PPAPYROPHOSPHATE BINDING SITE | S - 130 |
Clusters included in this Subclass |
CLUSTER: EH.1.1 |
CLUSTER: EH.1.76 |
CLUSTER: EH.2.1 |
CLUSTER: EH.2.80 |
CLUSTER: EH.3.1 |
CLUSTER: EH.3.125 |