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Information on SUBCLASS 1.1.5
Subclass Accession number: 941
Subclass: 1.1.5 PSSM
Type: EH beta-alpha
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 76

Average sequence ID (%) : 9.9 +/- 13.0
Average RMSD (Å) : 0.472 +/- 0.184

Consensus geometry
d (Å): 11 delta (°): 0-45 theta (°): 90-135 rho (°): 225-270
Consensus Sequence: XhXXX
(φψ)-conformation: bbpaa
Pattern: xxx[acfgilmptv][adgnpstv]x[adegknqrst]xxx
Conservation:0.319-0.321-1.3870.9761.489-1.2581.1560.178-0.368-0.783
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1aky_*_1141aky   -117126ELKVDDELLVEEE--HHHHHxxxbxaaaaa
1amu_A_2501amu   A251259LYIILKDTI.EEE--HHHH.bbxxxaaaa.
1aor_A_171aor   A2029VEEYDEELAKEEE--HHHHHbbbbxaaaaa
1aqu_A_1241aqu   A127136YLCRNAKDVAEEE--HHHHHbbbbpaaaaa
1b24_A_1601b24   A162171VLNISLRDRIEEEE-GGGHHbbbxpaaaaa
1bx4_A_161bx4   A2029SAVVDKDFLDEEE--HHHHHbbxbbaaaaa
1cke_A_1431cke   A146155FLDASSEERAEEE--HHHHHbbbbxaaaaa
1cr5_A_961cr5   A99108AKAFDLFKYSEEE--HHHHHbbpbbaaaaa
1dar_*_6681dar   -676685YQEVPKQVQEEEE--HHHHHbbxxxaaaaa
1dmg_A_131dmg   A1624TLEISDFVF.EEE--HHHH.bxxbxaaaa.
1dqn_A_1031dqn   A104113SVVFDEEDLKEEE--HHHHHbxbxxaaaaa
1dqs_A_3801dqs   A380388.SVVANEDIR.EE--HHHHH.bxbxaaaaa
1dxy_*_1871dxy   -187195.DYVSLEDLF.EE--HHHHH.bxbxaaaaa
1dy5_A_431dy5   A4655FVHESLADVQEE-S-HHHHHbbbbpaaaaa
1e2h_A_2021e2h   A205214LGALPEDRHIEEE--HHHHHbbbbwaaaaa
1ekr_A_241ekr   A3342FVTMRSETLAEEE--HHHHHbbxbxaaaaa
1es6_A_2581es6   A260269GIEVPETLVLEEE--HHHHHbbxbxaaaaa
1f3u_A_171f3u   A2029LVKVPKYLSQEEE--HHHHHbbxbxaaaaa
1f44_A_2091f44   A210219EKALSLGVTKEEE--HHHHHbbxbxaaaaa
1fmj_A_1791fmj   A182191YLARDPRDVAEEE--HHHHHbbbbpaaaaa
1fp5_A_3961fp5   A402411TLPVGTRDWIEEE--HHHHHbbwbxaaaaa
1gky_*_501gky   -5059YNFVSVDEFKEEE--HHHHHbbxbxaaaaa
1h16_A_7041h16   A707716VNVMNREMLLEEE--HHHHHbbbbxaaaaa
1hl9_A_4251hl9   A427435EITVPKKLL.EEE--HHHH.bbbbpaaaa.
1i5z_A_1641i5z   A164173QIKITRQEIGEEE--HHHHHbbbbxaaaaa
1iyk_A_2911iyk   A292301VQLFTEEEFKEEE--HHHHHbxbbxaaaaa
1j8m_F_2811j8m   F281290LEVFNPRRFVEEE--HHHHHbbxbbaaaaa
1j99_A_1151j99   A118127YLMRNPRDVLEEE--HHHHHbbbbpaaaaa
1jce_A_1961jce   A196204.VAIGERTAE.EE--HHHHH.bxbxaaaaa
1jey_B_3191jey   B320329IVPFSKVDEEEEE--HHHHHbbwbxaaaaa
1jj2_O_211jj2   O2129.VWFNPERQG.EEE-GGGHH.xbbpaaaaa
1k0i_A_971k0i   A97106VTVYGQTEVTEEE--HHHHHbbxbpaaaaa
1k1x_A_2471k1x   A247256INLMTYSEYLEEE--HHHHHbbxbxaaaaa
1k6d_A_941k6d   A95104VVLVPQGTLIEEE--HHHHHbbxbpaaaaa
1kgd_A_7841kgd   A784792.YFVSHDQMM.EE--HHHHH.bxbxaaaaa
1kht_A_1171kht   A120129VVETTGDEILEEE--HHHHHbxbbxaaaaa
1knq_A_1051knq   A109118YLKGDFDVIEEEE--HHHHHxxxbxaaaaa
1knz_A_1361knz   A136145IIKCTKLMRDEEE--HHHHHbbbbxaaaaa
1kqf_A_1221kqf   A122130.QRISWEEAF.EE--HHHHH.bxbxaaaaa
1kyf_A_7501kyf   A755764TLICADDLQTEEE--HHHHHbbbbpaaaaa
1l1l_A_6901l1l   A690699KEPIDKETYEEEE--HHHHHbbxbxaaaaa
1l4u_A_971l4u   A99108YLEISAAEGVEEE--HHHHHxxxbxaaaaa
1l5j_A_6061l5j   A608617TIKLNKEPIIEE---HHHHHbbxbxaaaaa
1l6x_A_3001l6x   A305314VLTVLHQDWLEEE--HHHHHbbxbxaaaaa
1lci_*_2841lci   -284293SALLVPTLFSEEE--HHHHHbbbbxaaaaa
1nnf_A_281nnf   A3039LNSGKSEQLAEEE--HHHHHxbxbxaaaaa
1np3_A_1781np3   A178187IIETTFKDETEEE--HHHHHbxxbbaaaaa
1nst_A_6981nst   A701710TILINPADRAEEE--HHHHHbbbbpaaaaa
1nth_A_201nth   A2028.EKCTQDDWD.EE--HHHHH.xxbxaaaaa
1nx4_A_171nx4   A1725.AYIDHRDFL.EE--HHHHH.bxbpaaaaa
1o97_D_3011o97   D302311GIVADIFDIEEE-S-HHHHHbbxbxaaaaa
1oe0_A_1491oe0   A152161YLRTSPEVAYEEE--HHHHHxxxbbaaaaa
1ojr_A_321ojr   A3442TLRLDDADI.EEE--HHHH.bbxbbaaaa.
1ooy_A_931ooy   A94103VELTPQGTLAEEE--HHHHHbbxbpaaaaa
1p5z_B_1741p5z   B177186YLQATPETCLEEE--HHHHHbxxbxaaaaa
1p6x_A_1771p6x   A181190VTTLNVEEHIEEE--HHHHHxxbbpaaaaa
1pn0_A_1131pn0   A113121.VVLHQGRIE.EE--HHHHH.bbbxaaaaa
1poi_A_971poi   A98107MEDYSQDVIYEEE--HHHHHbbbbxaaaaa
1puc_*_411puc   -4148.VMLPKAML..EE--HHHH..bbxxaaaa.
1q44_A_1561q44   A159168YCCRNPKDMFEEE--HHHHHxbxbpaaaaa
1q67_A_1521q67   A155164MGIVPNSVVNEEE--HHHHHbxbbxaaaaa
1qf9_A_1101qf9   A116125FFDCPEEVMTEEE--HHHHHbxxbxaaaaa
1qme_A_3691qme   A369377ATIRDWDVN.EEE--HHHH.xbxbxaaaa.
1qmg_A_3021qmg   A303312TFATTLEQEYEEE--HHHHHbbxbbaaaaa
1rlr_*_2051rlr   -205213.ISLPTPIMS.EE--HHHHH.bbbxaaaaa
1ry9_A_511ry9   A5867FDAPSDVKLQEE---HHHHHxpxxxaaaaa
1uj2_A_1511uj2   A154163FVDTDADTRLEEE--HHHHHbxxbpaaaaa
1ujp_A_941ujp   A95104FLMTYLNPVLEEE--HHHHHbxxbxaaaaa
1vht_A_1261vht   A129138VVDVSPETQLEEE--HHHHHbxbbxaaaaa
1zin_*_1091zin   -112121HIDVRQDVLMEEE--HHHHHxxxbxaaaaa
2ak3_A_1082ak3   A111120NLNVPFEVIKEEE--HHHHHbxbbwaaaaa
2bc2_A_1042bc2   A104113KAHSTALTAEEEE-BHHHHHxxxbxaaaaa
2cb5_A_3002cb5   A300309YNNQPIDFLKEEE--HHHHHbbxbxaaaaa
2dap_*_2242dap   -227236VNFIDEATFDEEE--HHHHHbbbbxaaaaa
3gcb_*_2973gcb   -299308YLNVDNETLSEEE--HHHHHbbxbxaaaaa
4tmk_A_1354tmk   A138147YLDVTPEVGLEEE--HHHHHxxxbxaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1aky_*_1141aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 118
1aky_*_1141aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE R - 128
1aky_*_1141aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE I - 129
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE R - 130
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE D - 134
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE V - 137
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE S - 138
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE Y - 141
1aqu_A_1241aqu   A     A3PADENOSINE-3'-5'-DIPHOSPHATE F - 142
1aqu_A_1241aqu   A     ESTESTRADIOL F - 142
1bx4_A_161bx4   A     ADNADENOSINE L - 16
1bx4_A_161bx4   A     ADNADENOSINE L - 17
1bx4_A_161bx4   A     ADNADENOSINE D - 18
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED L - 28
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED D - 29
1bx4_A_161bx4   A     MO4MAGNESIUM ION, 4 WATERS COORDINATED K - 30
1dqn_A_1031dqn   A     IMUPHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN -2-YLMETHYL] ESTER E - 103
1dxy_*_1871dxy   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 191
1dy5_A_431dy5   A     ACTACETATE ION V - 43
1dy5_A_431dy5   A     ACTACETATE ION N - 44
1dy5_A_431dy5   A     ACTACETATE ION T - 45
1dy5_A_431dy5   A     ACTACETATE ION F - 46
1dy5_A_431dy5   A     IPAISOPROPYL ALCOHOL H - 48
1dy5_A_431dy5   A     IPAISOPROPYL ALCOHOL E - 49
1dy5_A_431dy5   A     IPAISOPROPYL ALCOHOL S - 50
1dy5_A_431dy5   A     IPAISOPROPYL ALCOHOL Q - 55
1dy5_A_431dy5   A     IPAISOPROPYL ALCOHOL A - 56
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE R - 185
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE D - 189
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE V - 192
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE S - 193
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE S - 194
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE H - 196
1fmj_A_1791fmj   A     A3PADENOSINE-3'-5'-DIPHOSPHATE H - 197
1fmj_A_1791fmj   A     RTLRETINOL H - 197
1gky_*_501gky   *     5GPGUANOSINE-5'-MONOPHOSPHATE Y - 50
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE R - 169
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE Q - 170
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE E - 171
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE I - 172
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE G - 173
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE Q - 174
1i5z_A_1641i5z   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL I - 175
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE I - 175
1i5z_A_1641i5z   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL V - 176
1i5z_A_1641i5z   A     CMPADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE V - 176
1j99_A_1151j99   A     AND3-BETA-HYDROXY-5-ANDROSTEN-17-ONE F - 133
1j99_A_1151j99   A     AND3-BETA-HYDROXY-5-ANDROSTEN-17-ONE W - 134
1jce_A_1961jce   A     MSESELENOMETHIONINE R - 201
1jce_A_1961jce   A     MSESELENOMETHIONINE A - 203
1jce_A_1961jce   A     MSESELENOMETHIONINE K - 207
1k0i_A_971k0i   A     PHBP-HYDROXYBENZOIC ACID V - 99
1k0i_A_971k0i   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 102
1kgd_A_7841kgd   A     FMTFORMIC ACID Y - 784
1l4u_A_971l4u   A     ADPADENOSINE-5'-DIPHOSPHATE L - 100
1l4u_A_971l4u   A     PTPLATINUM (II) ION A - 104
1l4u_A_971l4u   A     ADPADENOSINE-5'-DIPHOSPHATE E - 106
1l4u_A_971l4u   A     ADPADENOSINE-5'-DIPHOSPHATE R - 110
1l6x_A_3001l6x   A     NAGN-ACETYL-D-GLUCOSAMINE R - 301
1l6x_A_3001l6x   A     MANALPHA-D-MANNOSE R - 301
1l6x_A_3001l6x   A     NAGN-ACETYL-D-GLUCOSAMINE V - 303
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE D - 708
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE Y - 711
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE S - 712
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE W - 713
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE Q - 715
1nst_A_6981nst   A     A3PADENOSINE-3'-5'-DIPHOSPHATE H - 716
1nx4_A_171nx4   A     MSESELENOMETHIONINE Y - 18
1o97_D_3011o97   D     FADFLAVIN-ADENINE DINUCLEOTIDE A - 305
1o97_D_3011o97   D     FADFLAVIN-ADENINE DINUCLEOTIDE D - 306
1o97_D_3011o97   D     FADFLAVIN-ADENINE DINUCLEOTIDE I - 307
1o97_D_3011o97   D     FADFLAVIN-ADENINE DINUCLEOTIDE F - 308
1oe0_A_1491oe0   A     TTPTHYMIDINE-5'-TRIPHOSPHATE L - 153
1oe0_A_1491oe0   A     TTPTHYMIDINE-5'-TRIPHOSPHATE R - 167
1oe0_A_1491oe0   A     MGMAGNESIUM ION R - 167
1ojr_A_321ojr   A     ZNZINC ION N - 32
1ojr_A_321ojr   A     PO4PHOSPHATE ION N - 32
1ojr_A_321ojr   A     2HADIHYDROXYACETONE N - 32
1p5z_B_1741p5z   B     ADPADENOSINE-5'-DIPHOSPHATE R - 188
1p5z_B_1741p5z   B     ADPADENOSINE-5'-DIPHOSPHATE I - 189
1p5z_B_1741p5z   B     ADPADENOSINE-5'-DIPHOSPHATE L - 191
1p5z_B_1741p5z   B     MO3MAGNESIUM ION, 3 WATERS COORDINATED R - 192
1p5z_B_1741p5z   B     ADPADENOSINE-5'-DIPHOSPHATE R - 192
1pn0_A_1131pn0   A     IPHPHENOL V - 113
1pn0_A_1131pn0   A     IPHPHENOL V - 114
1pn0_A_1131pn0   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 117
1pn0_A_1131pn0   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 121
1qf9_A_1101qf9   A     ADPADENOSINE-5'-DIPHOSPHATE R - 127
1qf9_A_1101qf9   A     ALFTETRAFLUOROALUMINATE ION L - 128
1qf9_A_1101qf9   A     ADPADENOSINE-5'-DIPHOSPHATE L - 128
1qf9_A_1101qf9   A     ADPADENOSINE-5'-DIPHOSPHATE K - 130
1qf9_A_1101qf9   A     ALFTETRAFLUOROALUMINATE ION R - 131
1qf9_A_1101qf9   A     MGMAGNESIUM ION R - 131
1qf9_A_1101qf9   A     ADPADENOSINE-5'-DIPHOSPHATE R - 131
1qf9_A_1101qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE R - 131
1qmg_A_3021qmg   A     DMV2,3-DIHYDROXY-VALERIANIC ACID E - 311
1qmg_A_3021qmg   A     MNMANGANESE (II) ION E - 311
1qmg_A_3021qmg   A     DMV2,3-DIHYDROXY-VALERIANIC ACID D - 315
1qmg_A_3021qmg   A     APX2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHORIBOSE D - 315
1qmg_A_3021qmg   A     MNMANGANESE (II) ION D - 315
1qmg_A_3021qmg   A     MNMANGANESE (II) ION I - 316
1qmg_A_3021qmg   A     DMV2,3-DIHYDROXY-VALERIANIC ACID G - 318
1qmg_A_3021qmg   A     DMV2,3-DIHYDROXY-VALERIANIC ACID E - 319
1qmg_A_3021qmg   A     MNMANGANESE (II) ION E - 319
1uj2_A_1511uj2   A     ADPADENOSINE-5'-DIPHOSPHATE R - 165
1uj2_A_1511uj2   A     C5PCYTIDINE-5'-MONOPHOSPHATE R - 166
1uj2_A_1511uj2   A     ADPADENOSINE-5'-DIPHOSPHATE R - 166
1uj2_A_1511uj2   A     ADPADENOSINE-5'-DIPHOSPHATE L - 168
1uj2_A_1511uj2   A     MGMAGNESIUM ION R - 169
1uj2_A_1511uj2   A     C5PCYTIDINE-5'-MONOPHOSPHATE R - 169
1uj2_A_1511uj2   A     ADPADENOSINE-5'-DIPHOSPHATE R - 169
1uj2_A_1511uj2   A     C5PCYTIDINE-5'-MONOPHOSPHATE D - 170
1uj2_A_1511uj2   A     ADPADENOSINE-5'-DIPHOSPHATE E - 173
1vht_A_1261vht   A     BA3BIS(ADENOSINE)-5'-TRIPHOSPHATE V - 130
1vht_A_1261vht   A     BA3BIS(ADENOSINE)-5'-TRIPHOSPHATE R - 140
1vht_A_1261vht   A     BA3BIS(ADENOSINE)-5'-TRIPHOSPHATE T - 141
1vht_A_1261vht   A     BA3BIS(ADENOSINE)-5'-TRIPHOSPHATE R - 144
1vht_A_1261vht   A     BA3BIS(ADENOSINE)-5'-TRIPHOSPHATE D - 145
1zin_*_1091zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE R - 123
1zin_*_1091zin   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE L - 124
3gcb_*_2973gcb   *     GOLGLYCEROL R - 314
4tmk_A_1354tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE R - 149
4tmk_A_1354tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE A - 150
4tmk_A_1354tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE A - 152
4tmk_A_1354tmk   A     T5AP1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE R - 153
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1oe0_A_1491oe0   A AC1TTP BINDING SITE FOR CHAIN AR - 167
1ojr_A_321ojr   A POAPO4 A1276 BINDING SITEN - 32

Clusters included in this Subclass
CLUSTER: EH.1.5
CLUSTER: EH.2.6
CLUSTER: EH.3.3