Extending signalling pathways with protein-interaction networks. Application to apoptosis.

Extending signalling pathways with protein-interaction networks. Application to apoptosis.
Joan Planas-Iglesias, Emre Guney, Javier Garcia-Garcia, Kevin A. Robertson, Sobia Raza, Tom C. Freeman, Peter Ghazal and Baldo Oliva.
OMICS. 2012 May;16(5):245-56. Epub 2012 Mar 2. (PMID: 22385281)

Acronyms index for "Extending signalling pathways with protein-interaction networks. Application to apoptosis."

Acronym	Meaning	Reference or explanation
ALD	Apoptosis Linking Degree	Analogous measure to Cancer Linking Degree for apoptosis-related networks. Used as a scoring system in this work, denotes the number of connexions with a known apoptotsis protein a given node has.
FF	Functional Flow	Scoring method described by Nabieva et al that propagates a phenotype-repaled annotation on nodes in a network to its neighboring nodes.
iALD	iterative Apoptosis Linking Degree	Scoring system that iterativelly transfers part of ALD score to neighboring nodes in the network (work in preparation).
JEV	Joint eValue	Harmonic mean of the eValues of the alignments between two proteins and their known interacting interologs.
KW	ProMiner	Validation method based on the use of KeyWord search in BIANA.
PM	ProMiner	Text-mining validation method based on the use of ProMiner.
PPI	Protein-Protein Interaction
SC	STRING Combined score	Conficence score provided by STRING that summarizeds the relevance of different sources of evidence for a PPI prediction.