Extending signalling pathways with protein-interaction networks. Application to apoptosis.

New protein candidates for "Extending signalling pathways with protein-interaction networks. Application to apoptosis."

The best combinations of scoring methods from the four networks analyzed and the two validation systems used during the analysis encompassed 273 new protein candidates in total. These proteins are our predictions of new members of the apoptosis pathways. Here, we present information about their known functions and the complete list of the protein candidates.

Known functions of proteins predicted to be involved in apoptosis by the scoring methods presented in the paper

273 new protein candidates obtained from the best combinations of ALD, iALD, FF, and SC. These candiates are unique proteins not present in any validation set that were yelded as predictions by the best combination of scoring methods from each analyzed apoptosis-related network. The link on the total number of new candidates leads to the description of the particular protein candidates.