Information on SUBCLASS 6.1.1 |
Subclass Accession number: 5851
Subclass: 6.1.1 Type: HE alpha-beta DB: ArchDB95 Image coordinates: Consensus coordinates: |
Number of loops: 72 Average sequence ID (%) : 17.1 +/- 17.1 Average RMSD (Å) : 0.665 +/- 0.199 Consensus geometry
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Consensus Sequence: | XhchXXpphX |
(φψ)-conformation: | aalbpaaabb |
Pattern: | x | [afgilmvy] | x | x | x | [acfklmtv] | [adegknqrs] | [acfikltv] | [dehknpqrst] | x | [adegknqrst] | [cdehknqrstw] | [cilmtv] | x | x |
Conservation: | -1.303 | 0.260 | -0.282 | -0.503 | -0.906 | -0.618 | 1.334 | 1.196 | -0.245 | -0.466 | 0.382 | 0.566 | 1.962 | -1.378 | -1.000 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a5z_*_166 | 1a5z | - | 175 | 188 | LIAQHCGFSPRSVH. | HHHHHHT--GGGEE. | aaaaaavbxaaabb. |
1aj2_*_157 | 1aj2 | - | 170 | 184 | ARCEQAGIAKEKLLL | HHHHHHT--GGGEEE | aaaaaavbxaaaxbb |
1auo_A_81 | 1auo | A | 96 | 110 | EAQKRTGIDASRIFL | HHHHHTT--GGGEEE | aaaaaavxxaaabbb |
1b8p_A_160 | 1b8p | A | 169 | 182 | QIAAKTGKPVSSIE. | HHHHHHT--GGGEE. | aaaaaavbxaaaxb. |
1bu6_O_49 | 1bu6 | O | 62 | 76 | EVLTKADISSDQIAA | HHHHHHT--GGGEEE | aaaaaavbxaaaxab |
1dpt_A_70 | 1dpt | A | 83 | 97 | FLTKELALGQDRILI | HHHHHHT--GGGEEE | aaaaaalbxaaabbb |
1eg5_A_48 | 1eg5 | A | 52 | 66 | KVAKVLGVSPSEIFF | HHHHHHTS-GGGEEE | aaaaaavbxaaabbb |
1elu_A_54 | 1elu | A | 70 | 84 | ALAETFNVDPNTITI | HHHHHTTS-GGGEEE | aaaaaalbxaaabbx |
1euv_B_46 | 1euv | B | 51 | 65 | AFAKRQGKEMDSLRF | HHHHHTT--GGGEEE | aaaaaavbxaaabbb |
1eye_A_149 | 1eye | A | 162 | 176 | ADAVAAGVDPARLVL | HHHHHTT--GGGEEE | aaaaaagxxaaaxbx |
1ez4_A_164 | 1ez4 | A | 173 | 186 | ALGKQFNVDPRSVD. | HHHHHHT--GGGEE. | aaaaaalbpaaabx. |
1f08_A_243 | 1f08 | A | 249 | 263 | LMANMLNVREECLML | HHHHHHT--GGGEEE | aaaaaalbxaaabbb |
1f6y_A_133 | 1f6y | A | 145 | 159 | AAADEFGLPMEDLYI | HHHHHHT--GGGEEE | aaaaaavxpaaabbx |
1feh_A_335 | 1feh | A | 335 | 349 | YYPSISGLDPKNVFT | HHHHTT---GGGEEE | aaaaaavxxaaaxbb |
1ffv_B_239 | 1ffv | B | 245 | 259 | VVSMLSGIPESKVRI | HHHHHH---GGGEEE | aaaaaavxpaaabbb |
1ffv_B_526 | 1ffv | B | 533 | 547 | IIATELGIPSEVIQV | HHHHHHT--GGGEEE | aaaaaavbpaaaxxb |
1ffv_B_566 | 1ffv | B | 588 | 602 | IAAHMLEVNENDLDW | HHHHHTTS-GGGEEE | aaaaaalbxaaabbx |
1fg7_A_61 | 1fg7 | A | 66 | 80 | NYAQYAGVKPEQVLV | HHHHHHTS-GGGEEE | aaaaaavbxaaabbb |
1fiq_C_1042 | 1fiq | C | 1049 | 1062 | VASKALKIPISKIY. | HHHHHTTS-GGGEE. | aaaaaalbwaaabb. |
1fiq_C_769 | 1fiq | C | 775 | 789 | FVAKMLGVPVNRILV | HHHHHHT--GGGEEE | aaaaaavbxaaaxbb |
1fj2_A_81 | 1fj2 | A | 96 | 110 | DQEVKNGIPSNRIIL | HHHHHTT--GGGEEE | aaaaaagbxaaabbb |
1g99_A_181 | 1g99 | A | 190 | 204 | RAALMLGKPAEETKI | HHHHHHTS-GGG-EE | aaaaaavbxaaabbb |
1gd0_A_69 | 1gd0 | A | 82 | 96 | LLAERLRISPDRVYI | HHHHHH---GGGEEE | aaaaaavbxaaabbb |
1gv0_A_144 | 1gv0 | A | 154 | 168 | FIAMELGVSMQDVTA | HHHHHHT--GGGEEE | aaaaaavbxaaaxbb |
1gv1_A_144 | 1gv1 | A | 154 | 167 | FIAMELGVSMQDIN. | HHHHHH---GGGEE. | aaaaaavbxaaabb. |
1gzd_A_249 | 1gzd | A | 250 | 264 | TKVKEFGIDPQNMFE | HHHHHTT--GGGEEE | aaaaaavxxaaabbx |
1h6d_A_119 | 1h6d | A | 124 | 137 | IVAAEYGVDPRKIY. | HHHHHTT--GGGEE. | aaaaaalxpaaabb. |
1hfo_A_69 | 1hfo | A | 82 | 96 | HLNTKLGIPKNRMYI | HHHHHH---GGGEEE | aaaaaavxxaaabbb |
1hye_A_149 | 1hye | A | 158 | 171 | AIAKFFGVHIDEVR. | HHHHHHT--GGGEE. | aaaaaavbxaaabb. |
1iat_A_249 | 1iat | A | 250 | 264 | TKVKEFGIDPQNMFE | HHHHHHT--GGGEEE | aaaaaagxpaaabbx |
1itx_A_314 | 1itx | A | 319 | 333 | QGHLDAGVPAAKLVL | HHHHHHT--GGGEEE | aaaaaagxxaaabbx |
1iv3_A_109 | 1iv3 | A | 115 | 129 | SLSRLMRLPQDRIGL | HHHHHHT--GGGEEE | aaaaaalbxaaabbb |
1iz9_A_157 | 1iz9 | A | 166 | 179 | QLAKKTGTGVDRIR. | HHHHHHT--GGGEE. | aaaaaavbpaaaxb. |
1j97_A_143 | 1j97 | A | 150 | 164 | KIAKIEGINLEDTVA | HHHHHHT--GGGEEE | aaaaaavbxaaabbb |
1jj2_W_25 | 1jj2 | W | 36 | 50 | HLAKHFSVDEDAVRL | HHHHHTT--GGGEEE | aaaaaalbxaaaxbb |
1jlr_A_171 | 1jlr | A | 178 | 192 | EVLLRLGVKEERIIF | HHHHHTT--GGGEEE | aaaaaagxxaaaxbx |
1k1e_A_84 | 1k1e | A | 90 | 104 | DLMKQAGVTAEQTAY | HHHHHHT--GGGEEE | aaaaaavbxaaabbb |
1kas_*_277 | 1kas | - | 285 | 299 | NALRDAGIEASQIGY | HHHHHHT--GGGEEE | aaaaaavbxaaaxab |
1l1q_A_131 | 1l1q | A | 138 | 152 | ELCETAGVKPENIYI | HHHHHTT--GGGEEE | aaaaaagxxaaabbb |
1lc5_A_62 | 1lc5 | A | 67 | 81 | ALARHHQVPASWILA | HHHHHHTS-GGGEEE | aaaaaalbxaaabbx |
1ldn_A_164 | 1ldn | A | 173 | 187 | LLGEYFSVAPQNVHA | HHHHHHTS-GGGEEE | aaaaaalbpaaaxbb |
1lld_A_151 | 1lld | A | 160 | 173 | LIAQQTGVNVKNVH. | HHHHHHT--GGGEE. | aaaaaavbxaaabb. |
1lm8_B_24 | 1lm8 | B | 30 | 44 | IVEGILKRPPDEQRL | HHHHHH---GGGEEE | aaaaaalbwaaabbb |
1mfi_A_69 | 1mfi | A | 82 | 96 | LLSDRLHISPDRVYI | HHHHHH---GGGEEE | aaaaaavxxaaabbb |
1n62_B_242 | 1n62 | B | 248 | 262 | VVSLISGLPEHKIHV | HHHHHH---GGGEEE | aaaaaavxxaaabbx |
1n62_B_532 | 1n62 | B | 539 | 553 | IIATELGIPADDIMI | HHHHHHT--GGGEEE | aaaaaavbwaaabbb |
1n62_B_576 | 1n62 | B | 594 | 608 | IAAHMLEVHEGDLEW | HHHHHHTS-GGGEEE | aaaaaalbxaaabbx |
1ndd_A_23 | 1ndd | A | 29 | 43 | RVEEKEGIPPQQQRL | HHHHHH---GGGEEE | aaaaaavxxaaaxbb |
1nnl_A_113 | 1nnl | A | 118 | 132 | HVASKLNIPATNVFA | HHHHHTT--GGGEEE | aaaaaalxxaaabbb |
1nrw_A_214 | 1nrw | A | 220 | 234 | RLAKQLNIPLEETAA | HHHHHTT--GGGEEE | aaaaaavbxaaabbb |
1o08_A_1149 | 1o08 | A | 1153 | 1167 | AAAHAVGVAPSESIG | HHHHHTT--GGGEEE | aaaaaavbxaaabbb |
1o22_A_135 | 1o22 | A | 135 | 149 | YFFESKGWNPGEYTF | HHHHHHT--GGGEEE | aaaaaavbxaaabbb |
1o6z_A_165 | 1o6z | A | 175 | 188 | VLSEEFDAPVQNVE. | HHHHHHT--GGGEE. | aaaaaalbxaaabb. |
1ono_A_226 | 1ono | A | 234 | 248 | EARWLFNASASQMEV | HHHHHHT--GGGEEE | aaaaaalbxaaabbb |
1p1c_A_193 | 1p1c | A | 194 | 208 | PALLEAGFQRENICT | HHHHHHT--GGGEEE | aaaaaagxbaaabbb |
1p3w_A_42 | 1p3w | A | 57 | 71 | QIADLVGADPREIVF | HHHHHHT--GGGEEE | aaaaaavbxaaaxbx |
1pze_A_165 | 1pze | A | 175 | 188 | YVADALSVSPRDVQ. | HHHHHHTS-GGGEE. | aaaaaalbxwaabb. |
1qlm_A_147 | 1qlm | A | 152 | 166 | HVADECGVDPENLYL | HHHHHHTS-GGGEEE | aaaaaavbxaaabbb |
1qq5_A_150 | 1qq5 | A | 155 | 169 | LVEEVLGVTPAEVLF | HHHHHH---GGGEEE | aaaaaavbxaaabbx |
1qzm_A_506 | 1qzm | A | 509 | 523 | KQIERNALKKGELTV | HHHHHTT--TTTEEE | aaaaaavbxaaabbb |
1rkq_A_198 | 1rkq | A | 204 | 218 | SLADVLGIKPEEIMA | HHHHHHT--GGGEEE | aaaaaavbxaaabbb |
1ryb_A_70 | 1ryb | A | 76 | 90 | PLAAYYQVPLRHILL | HHHHHTT--GGGEEE | aaaaaalxxaaaxxb |
1szw_A_55 | 1szw | A | 61 | 75 | ALAKFLKIHAREVSF | HHHHHTT--GGGEEE | aaaaaalbpaaabbb |
1t2d_A_151 | 1t2d | A | 161 | 174 | YISQKLNVCPRDVN. | HHHHHHTS-GGGEE. | aaaaaalbpaaaxb. |
1ur5_A_145 | 1ur5 | A | 155 | 169 | FIAMEAGVSVEDVQA | HHHHHHT--GGGEEE | aaaaaavbxaaabbb |
1vh8_A_115 | 1vh8 | A | 116 | 130 | KIAEDLQCDIEQVNV | HHHHHTTS-GGGEEE | aaaaaalbxaaabbb |
1vj5_A_163 | 1vj5 | A | 168 | 182 | FLLDTLKASPSEVVF | HHHHHHT--GGGEEE | aaaaaalbxaaabbb |
2rsl_A_13 | 2rsl | A | 21 | 35 | RALKDAGVKANRIFT | HHHHHTT--GGGEEE | aaaaaagxpaaaxbb |
4mdh_A_156 | 4mdh | A | 165 | 178 | QIALKLGVTSDDVK. | HHHHHHT--GGGEE. | aaaaaavxbaaabb. |
6ldh_*_164 | 6ldh | - | 173 | 186 | LMGERLGVHSCSCH. | HHHHHHTS-TTTEE. | aaaaaagbxaaaxb. |
7mdh_A_199 | 7mdh | A | 208 | 221 | QLALKAGVFYDKVS. | HHHHHTTS-GGGEE. | aaaaaalbxaaabb. |
9ldt_A_166 | 9ldt | A | 175 | 188 | LMGERLGVHPLSCH. | HHHHHHTS-GGGEE. | aaaaaavbpaaabb. |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1gv0_A_144 | 1gv0 | A | NAANAD BINDING SITE FOR CHAIN A | L - 146 |
1o6z_A_165 | 1o6z | A | AC2CL BINDING SITE FOR CHAIN A | R - 166 |
1ur5_A_145 | 1ur5 | A | AC8CD BINDING SITE FOR CHAIN C | E - 159 |
1ur5_A_145 | 1ur5 | A | AC5CD BINDING SITE FOR CHAIN A | E - 165 |
Clusters included in this Subclass |
CLUSTER: HE.5.6 |
CLUSTER: HE.6.0 |
CLUSTER: HE.7.1 |
CLUSTER: HE.7.110 |
CLUSTER: HE.8.1 |