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Information on SUBCLASS 1.2.1
Subclass Accession number: 8137
Subclass: 1.2.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 127

Average sequence ID (%) : 13.9 +/- 15.6
Average RMSD (Å) : 0.454 +/- 0.175

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 135-180 rho (°): 45-90
Consensus Sequence: XXchX
(φψ)-conformation: aalbb
Pattern: xx[adegkqrst][adeknqrst]x[degknqrs][acfgilmvwy]x[acfgilmpvy]x
Conservation:-0.489-0.1140.6910.488-0.6972.404-0.419-0.937-0.087-0.841
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4m_A_1261a4m   A140149GEQAFGIKVRHHHHH--EEEaaaaavbxbb
1a4s_A_2431a4s   A252261MSAKTVKHVTHHHTTT-EEEaaaaalxxbb
1a79_A_1421a79   A150159VAHSVRKKLLHHHHTT-EEEaaaaalbxbb
1a7t_A_571a7t   A6776VTDSLHAKVTHHHHH--EEEaaaaalbbxa
1ado_A_1601ado   A176185ICQQNGIVPIHHHHTT-EEEaaaaavbxxx
1ak2_*_291ak2   -3645LAKNFCVCHLHHHHHT-EEEaaaaalbxxb
1ako_*_441ako   -4655EVAKLGYNVFHHHHTT-EEEaaaaavbxbb
1aky_*_171aky   -2433LQERFHAAHLHHHHH--EEEaaaaalxxxb
1alq_*_331alq   -3645LEKKYNAHIGHHHHHT-EEEaaaaalbbbb
1b1y_A_3571b1y   A367376AGWREGLNVSHHHHTT--EEaaaaavxxbb
1bhe_*_1361bhe   -140148DAKVKKLKQ.HHHHHT-EE.aaaaavbbx.
1bj4_A_2111bj4   A217226IADENGAYLMHHHHTT-EEEaaaaalbxbb
1bs0_A_1871bs0   A193202VTQQHNGWLMHHHHTT-EEEaaaaavxbbb
1bsg_*_281bsg   -3645LERASGARLGHHHHHTSEEEaaaaavbxbb
1bu6_O_4161bu6   O422431QSDILGTRVEHHHHHTSEEEaaaaavbxbx
1bue_A_301bue   A3645LETDFNGRIGHHHHHTSEEEaaaaavbbbb
1byb_*_3261byb   -331340MLSRHHAILNHHHHTT-EEEaaaaalxxxx
1byb_*_701byb   -7887LVQECGLTLQHHHHTT-EEEaaaaavbxbb
1c3c_A_1921c3c   A198206ALSYLGLKP.HHHHTT-EE.aaaaavbbx.
1ceo_*_2551ceo   -268277FREKKKCKLYHHHHH--EEEaaaaalxbbb
1cf2_O_901cf2   O97106MYKEKGIKAIHHHHTT-EEEaaaaavbxbb
1cjx_A_2851cjx   A287296QLQARGILLDHHHHHT-EEEaaaaavxbbb
1clx_A_601clx   A6877WAAQNGQTVHHHHHTT-EEEaaaaavbxbb
1d3c_A_1151d3c   A124133AAHAKNIKVIHHHHTT-EEEaaaaavbxbb
1d3v_A_701d3v   A8695ETQKNGTISVHHHHTT-EEEaaaaavbxxb
1d7u_A_2251d7u   A232241KCEARGMLLIHHHHHT-EEEaaaaavxxbb
1d8w_A_1241d8w   A129138WAKANQLGLDHHHHTT-EEEaaaaavbxbb
1dfo_A_1831dfo   A189198IADSIGAYLFHHHHTT-EEEaaaaavxxbb
1doz_A_2721doz   A276285VTDDIGASYYHHHHHT-EEEaaaaavxxbb
1dp4_A_1631dp4   A175184VRERLNITVNHHHHH--EEEaaaaavxxbx
1dqw_A_741dqw   A8089LSAKYNFLLFHHHHHT-EEEaaaaavbxbb
1duv_G_1101duv   G116125LAEYASVPVWHHHHHSS-EEaaaaavbpbb
1eg7_A_13531eg7   A13691378NIGKFGVPAVHHHTTT--EEaaaaavbxbb
1eix_A_471eix   A6069ELQQRGFDIFHHHHTT--EEaaaaavxxbb
1eny_*_1591eny   -178187EAGKYGVRSNHHHTTT-EEEaaaaavxxbb
1eon_A_371eon   A5564IAEKHGYIVEHHHHTT-EEEaaaaavxxbb
1erz_A_2111erz   A222231GSYQNGAWSAHHHHHT-EEEaaaaalbxbb
1euz_A_2221euz   A231240AKEQLGMTVVHHHHH--EEEaaaaavxxxa
1ex7_A_821ex7   A8796QVSKSGKTCIHHHHHTSEEEaaaaavbxxb
1ezv_A_791ezv   A8493VAAKEGLALSHHHHTT-EEEaaaaavbbbb
1f06_A_951f06   A105114AATAAGNVALHHHHHT-EEEaaaaavbbbx
1f2j_A_1701f2j   A186195LSQLCGLVPIHHHHTT-EEEaaaaavbxxx
1fa2_A_3281fa2   A333342MLARHHATLNHHHHTT-EEEaaaaalbxxb
1fa2_A_711fa2   A7988LVKKCGLKIQHHHHTT-EEEaaaaavbxbb
1fba_A_1601fba   A176185ICQSQRIVPIHHHHTT-EEEaaaaavbxxx
1fdj_A_11601fdj   A11761185ICQQNGLVPIHHHHTT-EEEaaaaavbxxx
1ff9_A_1091ff9   A111120AAKDAGITVMHHHHTT-EEEaaaaavbbbx
1fg7_A_1141fg7   A116125SAETIGVECRHHHHHT-EEEaaaaagbpbb
1fui_A_1941fui   A197206FESWLGMKVQHHHHH--EEEaaaaavbbbb
1fxp_A_10601fxp   A10701079VKEEFGLKITHHHHH--EEEaaaaavbxbb
1fy2_A_461fy2   A5665VLAPLGVNVTHHGGGT-EEEaaaaavbbxb
1g6a_A_271g6a   A3645IEVSLSARIGHHHHTT-EEEaaaaalbxbb
1g8t_A_791g8t   A7988ANAALKVDRGHHHHH-EEEEaaaaalbbxx
1gc0_A_1691gc0   A175184IARKHGATVVHHGGGT-EEEaaaaalxxxb
1ghp_A_321ghp   A3645LEKKYNAHIGHHHHTT-EEEaaaaalbbbb
1gpj_A_2011gpj   A207215LARDLGGEA.HHHHHT-EE.aaaaavbbx.
1gs5_A_1611gs5   A168177LAATLGADLIHHHHHT-EEEaaaaavxxbb
1gve_A_1791gve   A182191CLRHFGLRFYHHHHHT-EEEaaaaavbxbb
1gyn_A_1501gyn   A163172RMSKIGMTLEHHHTTT-EEEaaaaavxbbb
1gyn_A_801gyn   A96105MAEHYGVPVIHHHHHT-EEEaaaaavbwbb
1h05_A_291h05   A3948EAAELGLKAVHHHHTT-EEEaaaaavbbxb
1h2w_A_4861h2w   A491500FVRHMGGVLAHHHHH--EEEaaaaalxbbb
1h7b_A_4161h7b   A430439WTERTGFAFSHHHHH--EEEaaaaavxxxb
1hkv_A_1391hkv   A148157IAGEAGIVQDHHHHHT--EEaaaaavbbxx
1hqt_A_1941hqt   A199208HCQARGLEVTHHHHHT-EEEaaaaavbxbb
1hzo_A_281hzo   A3645LEKYSQGRLGHHHHHTSEEEaaaaavbbbb
1hzy_A_1101hzy   A116125VSRAADVHIVHHHHHT-EEEaaaaavbxbx
1i24_A_2391i24   A245254VQAAVGHPLTHHHHHT--EEaaaaavxxxx
1i2s_A_321i2s   A3645LEEQFDAKLGHHHHHT-EEEaaaaalbbbb
1ibj_A_2361ibj   A242251MAHAQGALVLHHHTTT-EEEaaaaavbxbb
1itw_A_2291itw   A242251DAKKQGVLLSHHHHHT-EEEaaaaavbxxb
1ivn_A_811ivn   A94103DVKAANAEPLHHHHTT-EEEaaaaalbxwb
1iys_A_291iys   A3645LEKSSGGRLGHHHHHTSEEEaaaaavbbbb
1j11_A_3131j11   A319328AFKSAKLDVTHHHHHT-EEEaaaaavbxbb
1j5s_A_2621j5s   A279288MNQETNWVTQHHHHHT-EEEaaaaalxxbx
1jf9_A_1831jf9   A189198LAHQHGAKVLHHHHTT-EEEaaaaavxxbb
1jq5_A_961jq5   A105114VADELDAYIVHHHHHT-EEEaaaaalxxbb
1jqo_A_6101jqo   A627636VAKRYGVKLTHHHTTT-EEEaaaaalbxxb
1jva_A_5161jva   A525534YAEKLNLCAEHHHHTT-EEEaaaaalbbxx
1k6w_A_1901k6w   A203212LAQKYDRLIDHHHHHT-EEEaaaaalbxbb
1k87_A_2651k87   A274283KLEEKGFRYSHHHTTT-EEEaaaaagxbbb
1kht_A_1451kht   A162171YGVLTGATVKHHHHH--EEEaaaaavxxbb
1knw_A_1711knw   A177186VIQRHHLQLVHHHHTT-EEEaaaaalxbxa
1kor_A_111kor   A2029LKETYRAEVIHHHHHT-EEEaaaaalbxbx
1kpi_A_851kpi   A9099AVAEYDVNVIHHHHH--EEEaaaaalbxbb
1kqp_A_1281kqp   A146154IGGQEGLLV.HHHHHT-EE.aaaaavbxx.
1kvk_A_3131kvk   A321330VTAAHGLHSKHHHHTT-EEEaaaaavbbbb
1l7e_A_471l7e   A4958ALTAAGATIAHHHHHT-EEEaaaaagbxbb
1l9x_A_341l9x   A3948YLESAGARVVHHHHTT-EEEaaaaavbbbb
1lfw_A_2321lfw   A242251FLADKELDGSHHHHHT-EEEaaaaavbbeb
1lg2_A_3371lg2   A346355YLKQKGLGGAHHHHTT-SEEaaaaavxaeb
1lh0_A_11661lh0   A11701179VERDYGCKVIHHHHH--EEEaaaaalbbxx
1ll7_A_3571ll7   A366375YITKNGMGGGHHHHTT--EEaaaaalxaeb
1ltz_A_801ltz   A8796LMAATGWKIVHHHHHS-EEEaaaaavxbxb
1lvg_A_851lvg   A9099AVQAMNRICVHHHHTT-EEEaaaaalbxxb
1lya_B_2411lya   B247256LQKAIGAVPLHHHHHT-EEEaaaaavxbxa
1m56_A_4281m56   A440447IGKMSGRQ..HHHHHSEE..aaaaavbx..
1m7x_A_3151m7x   A324333AAHAAGLNVIHHHHTT-EEEaaaaavbxbb
1m7y_A_1751m7y   A184193EAEKRNLRVKHHHHTT--EEaaaaavbxxa
1m8p_A_2041m8p   A213222AARSRQANVLHHHHTT-EEEaaaaalbxbb
1mx3_A_2111mx3   A211219VERALGLQR.HHHHHT-EE.aaaaavbxb.
1n5m_A_1361n5m   A138147LAQVEGAVLVHHHHH--EEEaaaaavxbbb
1n7k_A_1161n7k   A129138LAKSYGAVVKHHHHTT-EEEaaaaavxxbb
1nj1_A_4391nj1   A445454VEEKVRVDILHHHHHT-EEEaaaaalbbxa
1nks_A_1471nks   A164173SAVLAGSTVKHHHHHT-EEEaaaaavbxbb
1now_A_3801now   A394403IIATINKGSIHHHHTT-EEEaaaaalbxbb
1nxu_A_1211nxu   A126135QAAEKGYIGIHHHHTT-EEEaaaaavxxbb
1o4s_A_1811o4s   A190199LAKKRNFYIIHHHHHT-EEEaaaaalbxbb
1o60_A_761o60   A8493LKDTFGVKIIHHHHH--EEEaaaaavxxbb
1o6i_A_3821o6i   A391400YIKQQQLGGVHHHHTT--EEaaaaalxaeb
1o94_A_801o94   A92101EVHKYGALAGHHHTTT-EEEaaaaavxxbb
1obr_*_2271obr   -240249MAQTNGYTPQHHHHH--EEEaaaaavxbxb
1od8_A_2181od8   A224233NFAALGVDVAHHHTTT-EEEaaaaavbxbb
1od8_A_621od8   A7079WAVQNGKQVRHHHHTT-EEEaaaaavbxbx
1pfk_A_1391pfk   A156165TSSSHQRISVHHHHHT-EEEaaaaalbbbb
1pox_A_1461pox   A156165RAYAHQGVAVHHHHHTSEEEaaaaalbbbb
1pq3_A_891pq3   A105114RAVSDGYSCVHHHHTT-EEEaaaaavxxxb
1q6o_A_921q6o   A101110VAKEFNGDVQHHHHTT-EEEaaaaalbbbb
1qf9_A_191qf9   A2635IVRDFGWVHLHHHHH--EEEaaaaavxxxb
1qlm_A_191qlm   A1927.AELLNVEVQ.HHHHT-EEE.aaaalbbbb
1qmh_A_501qmh   A5968ATEICGATVEHHHHHT-EEEaaaaalxbbb
1qo2_A_1771qo2   A183192IAIEAEVKVLHHHHHT-EEEaaaaalbxbb
1qw9_A_1091qw9   A115124WAKMVGAEVNHHHHHT-EEEaaaaavbxbx
1qwg_A_541qwg   A6372YYKDWGIKVYHHHTTT-EEEaaaaavbxbb
1r6x_A_2021r6x   A211220AAREANAKVLHHHHTT-EEEaaaaalbbbb
1rlv_A_2721rlv   A281290LAQNVRKRMVHHHHTT-EEEaaaaalbbxb
1spb_P_231spb   P2938VISEKGGKVQHHHHTT-EEEaaaaavxbpa
1tmo_*_2321tmo   -233242TQAYLGCEQLHHHHHT-EEEaaaaavbxbb
1ueh_A_971ueh   A99108SLHRHNVRLRHHHHTT-EEEaaaaavxxxb
1xgs_A_1291xgs   A138146EIRKRGFKP.HHHTTT-EE.aaaaavbbx.
1xgs_A_301xgs   A4048MIMELGGKP.HHHHTT-EE.aaaaagbbx.
1xyz_A_5181xyz   A521530YAEARGIKIGHHHHTT-EEEaaaaavbbbb
1zfj_A_3221zfj   A332341VAREYGKTIIHHHHTT-EEEaaaaavbbbb
2aaa_*_2162aaa   -219228YNKASGVYCVHHHHHTSEEEaaaaavbpbb
2acy_*_222acy   -2938EGKKLGLVGWHHHHTT-EEEaaaaavxbeb
2apr_*_2282apr   -234242VARAYGASD.HHHHHT-EE.aaaaavxbx.
2cev_A_682cev   A8493QVVQRGRFPLHHHHTT-EEEaaaaavbxwb
3pfk_*_1393pfk   -156165TATSHERTYVHHHHTT-EEEaaaaalbbbb
4pga_A_2974pga   A297304.DDKNDWVV..HHHHT-EE..aaaalxbb.
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a4m_A_1261a4m   A     PRH6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE C - 153
1a4m_A_1261a4m   A     PRH6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE M - 155
1ado_A_1601ado   A     13P1,3-DIHYDROXYACETONEPHOSPHATE E - 187
1ado_A_1601ado   A     13P1,3-DIHYDROXYACETONEPHOSPHATE E - 189
1aky_*_171aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE K - 17
1aky_*_171aky   *     IMDIMIDAZOLE K - 17
1aky_*_171aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE G - 18
1aky_*_171aky   *     IMDIMIDAZOLE G - 18
1aky_*_171aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE T - 19
1aky_*_171aky   *     IMDIMIDAZOLE T - 19
1aky_*_171aky   *     AP5BIS(ADENOSINE)-5'-PENTAPHOSPHATE Q - 20
1aky_*_171aky   *     IMDIMIDAZOLE A - 21
1aky_*_171aky   *     IMDIMIDAZOLE H - 32
1aky_*_171aky   *     IMDIMIDAZOLE A - 34
1bj4_A_2111bj4   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 228
1byb_*_701byb   *     GLCGLUCOSE I - 89
1byb_*_701byb   *     GLCGLUCOSE S - 91
1byb_*_3261byb   *     GLCGLUCOSE F - 341
1cf2_O_901cf2   O     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 90
1cf2_O_901cf2   O     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 94
1d7u_A_2251d7u   A     LCSL-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE D - 243
1d8w_A_1241d8w   A     MSESELENOMETHIONINE W - 129
1d8w_A_1241d8w   A     MSESELENOMETHIONINE N - 133
1d8w_A_1241d8w   A     MSESELENOMETHIONINE L - 135
1d8w_A_1241d8w   A     MSESELENOMETHIONINE D - 138
1d8w_A_1241d8w   A     MSESELENOMETHIONINE F - 139
1d8w_A_1241d8w   A     MSESELENOMETHIONINE N - 140
1dfo_A_1831dfo   A     PLGN-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] D - 200
1doz_A_2721doz   A     MO6MAGNESIUM ION, 6 WATERS COORDINATED E - 272
1eix_A_471eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID F - 69
1eix_A_471eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID D - 71
1eix_A_471eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID K - 73
1eny_*_1591eny   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 161
1eny_*_1591eny   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 165
1eny_*_1591eny   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 189
1eny_*_1591eny   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 190
1eny_*_1591eny   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE A - 191
1ex7_A_821ex7   A     5GPGUANOSINE-5'-MONOPHOSPHATE D - 98
1fa2_A_711fa2   A     DTT2,3-DIHYDROXY-1,4-DITHIOBUTANE I - 90
1fa2_A_711fa2   A     DTT2,3-DIHYDROXY-1,4-DITHIOBUTANE S - 92
1fdj_A_11601fdj   A     2FP1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM) E - 1187
1fdj_A_11601fdj   A     2FP1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM) E - 1189
1fg7_A_1141fg7   A     MSESELENOMETHIONINE S - 114
1fg7_A_1141fg7   A     MSESELENOMETHIONINE V - 115
1fg7_A_1141fg7   A     MSESELENOMETHIONINE S - 116
1fg7_A_1141fg7   A     MSESELENOMETHIONINE A - 117
1fxp_A_10601fxp   A     PO4PHOSPHATE ION D - 1081
1g8t_A_791g8t   A     SULSULFATE ANION D - 86
1g8t_A_791g8t   A     SULSULFATE ANION R - 87
1g8t_A_791g8t   A     MO5MAGNESIUM ION, 5 WATERS COORDINATED R - 87
1g8t_A_791g8t   A     SULSULFATE ANION G - 88
1g8t_A_791g8t   A     MO5MAGNESIUM ION, 5 WATERS COORDINATED G - 88
1g8t_A_791g8t   A     SULSULFATE ANION H - 89
1g8t_A_791g8t   A     MO5MAGNESIUM ION, 5 WATERS COORDINATED H - 89
1gc0_A_1691gc0   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) D - 186
1gs5_A_1611gs5   A     NLGN-ACETYL-L-GLUTAMATE A - 161
1gs5_A_1611gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 161
1gs5_A_1611gs5   A     MGMAGNESIUM ION A - 161
1gs5_A_1611gs5   A     NLGN-ACETYL-L-GLUTAMATE D - 162
1gs5_A_1611gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 162
1gs5_A_1611gs5   A     MGMAGNESIUM ION D - 162
1gs5_A_1611gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER L - 179
1gs5_A_1611gs5   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 180
1gve_A_1791gve   A     GOLGLYCEROL F - 180
1gve_A_1791gve   A     GOLGLYCEROL L - 183
1gve_A_1791gve   A     GOLGLYCEROL R - 184
1gve_A_1791gve   A     GOLGLYCEROL H - 185
1gve_A_1791gve   A     GOLGLYCEROL F - 186
1gve_A_1791gve   A     GOLGLYCEROL G - 187
1gve_A_1791gve   A     GOLGLYCEROL L - 188
1gve_A_1791gve   A     GOLGLYCEROL R - 189
1gve_A_1791gve   A     GOLGLYCEROL F - 190
1gve_A_1791gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 192
1gve_A_1791gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 193
1gve_A_1791gve   A     CITCITRIC ACID F - 193
1gyn_A_801gyn   A     CDCADMIUM ION I - 87
1gyn_A_801gyn   A     CDCADMIUM ION H - 91
1gyn_A_1501gyn   A     CDCADMIUM ION E - 174
1hkv_A_1391hkv   A     PLPPYRIDOXAL-5'-PHOSPHATE R - 161
1hqt_A_1941hqt   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 209
1hqt_A_1941hqt   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Y - 210
1hzy_A_1101hzy   A     EGLETHYLENE GLYCOL E - 115
1hzy_A_1101hzy   A     EGLETHYLENE GLYCOL V - 116
1hzy_A_1101hzy   A     EGLETHYLENE GLYCOL A - 119
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE A - 239
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE L - 240
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE R - 242
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE F - 243
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Q - 246
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE T - 254
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE V - 255
1i24_A_2391i24   A     UPGURIDINE-5'-DIPHOSPHATE-GLUCOSE Y - 256
1ibj_A_2361ibj   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 253
1jf9_A_1831jf9   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 200
1jq5_A_961jq5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 96
1jq5_A_961jq5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 97
1jq5_A_961jq5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 98
1jq5_A_961jq5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 100
1jq5_A_961jq5   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 103
1k6w_A_1901k6w   A     FEFE (III) ION H - 214
1k87_A_2651k87   A     GOLGLYCEROL I - 265
1k87_A_2651k87   A     GOLGLYCEROL A - 266
1k87_A_2651k87   A     GOLGLYCEROL E - 267
1k87_A_2651k87   A     LACLACTIC ACID D - 285
1knw_A_1711knw   A     PLPPYRIDOXAL-5'-PHOSPHATE H - 189
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER L - 11
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 12
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 13
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 14
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER I - 16
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER F - 31
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER T - 32
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER A - 33
1kor_A_111kor   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER D - 34
1kpi_A_851kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE S - 85
1kpi_A_851kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE T - 86
1kpi_A_851kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 101
1kpi_A_851kpi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE T - 102
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE F - 129
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE G - 132
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE N - 133
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE A - 136
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE R - 137
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE R - 139
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE Q - 143
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE Y - 144
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE G - 147
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE G - 148
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE G - 151
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE L - 152
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE L - 153
1kqp_A_1281kqp   A     ADJNICOTINAMIDE-ADENINE-DINUCLEOTIDE-ADENYLATE INTERMEDIATE V - 154
1lg2_A_3371lg2   A     EDO1,2-ETHANEDIOL M - 356
1lg2_A_3371lg2   A     EDO1,2-ETHANEDIOL W - 358
1ltz_A_801ltz   A     HBL7,8-DIHYDRO-L-BIOPTERIN V - 98
1lvg_A_851lvg   A     ADPADENOSINE-5'-DIPHOSPHATE D - 101
1lvg_A_851lvg   A     5GPGUANOSINE-5'-MONOPHOSPHATE D - 101
1m56_A_4281m56   A     HEAHEME-A A - 428
1m56_A_4281m56   A     CACALCIUM ION V - 429
1m56_A_4281m56   A     HEAHEME-A V - 429
1m56_A_4281m56   A     HEAHEME-A I - 432
1m56_A_4281m56   A     HEAHEME-A F - 433
1m56_A_4281m56   A     HEAHEME-A I - 436
1m7y_A_1751m7y   A     PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID T - 198
1nj1_A_4391nj1   A     ZNZINC ION C - 441
1nj1_A_4391nj1   A     ZNZINC ION G - 442
1nj1_A_4391nj1   A     MGMAGNESIUM ION E - 446
1nj1_A_4391nj1   A     MGMAGNESIUM ION V - 451
1nj1_A_4391nj1   A     MGMAGNESIUM ION D - 452
1nj1_A_4391nj1   A     MGMAGNESIUM ION I - 453
1now_A_3801now   A     IFG(2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM W - 405
1nxu_A_1211nxu   A     MSESELENOMETHIONINE G - 121
1nxu_A_1211nxu   A     MSESELENOMETHIONINE S - 122
1nxu_A_1211nxu   A     MSESELENOMETHIONINE Y - 123
1nxu_A_1211nxu   A     MSESELENOMETHIONINE G - 124
1nxu_A_1211nxu   A     MSESELENOMETHIONINE W - 125
1nxu_A_1211nxu   A     MSESELENOMETHIONINE Q - 126
1nxu_A_1211nxu   A     MSESELENOMETHIONINE A - 127
1nxu_A_1211nxu   A     MSESELENOMETHIONINE I - 133
1nxu_A_1211nxu   A     MSESELENOMETHIONINE G - 134
1nxu_A_1211nxu   A     MSESELENOMETHIONINE I - 135
1nxu_A_1211nxu   A     MSESELENOMETHIONINE C - 136
1o4s_A_1811o4s   A     PLPPYRIDOXAL-5'-PHOSPHATE D - 201
1o60_A_761o60   A     MSESELENOMETHIONINE E - 76
1o60_A_761o60   A     MSESELENOMETHIONINE G - 77
1o60_A_761o60   A     MSESELENOMETHIONINE L - 78
1o60_A_761o60   A     MSESELENOMETHIONINE K - 79
1o60_A_761o60   A     MSESELENOMETHIONINE I - 80
1o60_A_761o60   A     MSESELENOMETHIONINE E - 83
1o60_A_761o60   A     MSESELENOMETHIONINE L - 84
1o60_A_761o60   A     MSESELENOMETHIONINE T - 87
1o60_A_761o60   A     MSESELENOMETHIONINE F - 88
1o6i_A_3821o6i   A     GOLGLYCEROL K - 390
1o6i_A_3821o6i   A     GOLGLYCEROL Y - 391
1o6i_A_3821o6i   A     GOLGLYCEROL Q - 394
1o6i_A_3821o6i   A     GOLGLYCEROL Q - 395
1o6i_A_3821o6i   A     GOLGLYCEROL G - 398
1o6i_A_3821o6i   A     DPRD-PROLINE M - 401
1o6i_A_3821o6i   A     GOLGLYCEROL W - 403
1o6i_A_3821o6i   A     DPRD-PROLINE W - 403
1o6i_A_3821o6i   A     ARGARGININE W - 403
1o94_A_801o94   A     FMNFLAVIN MONONUCLEOTIDE E - 103
1od8_A_621od8   A     XDLXYLOSE-DERIVED ISOFAGOMINE LACTAM H - 81
1od8_A_621od8   A     XYPBETA-D-XYLOPYRANOSE H - 81
1od8_A_621od8   A     XDLXYLOSE-DERIVED ISOFAGOMINE LACTAM T - 82
1od8_A_2181od8   A     IMDIMIDAZOLE D - 231
1od8_A_2181od8   A     XDLXYLOSE-DERIVED ISOFAGOMINE LACTAM E - 236
1od8_A_2181od8   A     XYPBETA-D-XYLOPYRANOSE E - 236
1od8_A_2181od8   A     IMDIMIDAZOLE E - 236
1pfk_A_1391pfk   A     ADPADENOSINE-5'-DIPHOSPHATE R - 154
1pfk_A_1391pfk   A     MGMAGNESIUM ION R - 154
1pfk_A_1391pfk   A     ADPADENOSINE-5'-DIPHOSPHATE S - 158
1pq3_A_891pq3   A     SULSULFATE ANION R - 90
1q6o_A_921q6o   A     MGMAGNESIUM ION E - 112
1q6o_A_921q6o   A     LG6L-GULURONIC ACID 6-PHOSPHATE E - 112
1qf9_A_191qf9   A     ALFTETRAFLUOROALUMINATE ION K - 19
1qf9_A_191qf9   A     MGMAGNESIUM ION K - 19
1qf9_A_191qf9   A     ADPADENOSINE-5'-DIPHOSPHATE K - 19
1qf9_A_191qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE K - 19
1qf9_A_191qf9   A     ALFTETRAFLUOROALUMINATE ION G - 20
1qf9_A_191qf9   A     MGMAGNESIUM ION G - 20
1qf9_A_191qf9   A     ADPADENOSINE-5'-DIPHOSPHATE G - 20
1qf9_A_191qf9   A     ADPADENOSINE-5'-DIPHOSPHATE T - 21
1qf9_A_191qf9   A     ADPADENOSINE-5'-DIPHOSPHATE Q - 22
1qf9_A_191qf9   A     ALFTETRAFLUOROALUMINATE ION S - 36
1qf9_A_191qf9   A     MGMAGNESIUM ION S - 36
1qf9_A_191qf9   A     C5PCYTIDINE-5'-MONOPHOSPHATE S - 36
1qmh_A_501qmh   A     CITCITRIC ACID Q - 51
1qmh_A_501qmh   A     CITCITRIC ACID H - 52
3pfk_*_1393pfk   *     PO4PHOSPHATE ION R - 154
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1b1y_A_3571b1y   A M7MUTATED SITES TO INCREASE THERMOSTABILITYS - 376
1gs5_A_1611gs5   A NLGNLG BINDING SITE FOR CHAIN AA - 161
1gve_A_1791gve   A BC1GOL BINDING SITE FOR CHAIN AF - 180
1gve_A_1791gve   A BC1GOL BINDING SITE FOR CHAIN AR - 184
1gve_A_1791gve   A BC3GOL BINDING SITE FOR CHAIN BH - 185
1gve_A_1791gve   A BC1GOL BINDING SITE FOR CHAIN AL - 188
1gve_A_1791gve   A AC1NAP BINDING SITE FOR CHAIN AF - 193
1h05_A_291h05   A SO3SO4 BINDING SITE FOR CHAIN AR - 50
1hkv_A_1391hkv   A PLAPLP BINDING SITE FOR CHAIN AR - 161
1o6i_A_3821o6i   A PRADPR BINDING SITE FOR CHAIN AW - 403
1od8_A_621od8   A AC9XDL BINDING SITE FOR CHAIN AH - 81
1od8_A_2181od8   A AC9XDL BINDING SITE FOR CHAIN AE - 236
1qmh_A_501qmh   A RB1CITRATE BINDING SITE THAT IS INTERPRETED AS A PUTATIVE RNA BINDING SITEQ - 51

Clusters included in this Subclass
CLUSTER: HE.2.3
CLUSTER: HE.3.4
CLUSTER: HE.4.250
CLUSTER: HE.4.6
CLUSTER: HE.5.37