Information on SUBCLASS 2.2.2 |
Subclass Accession number: 7736
Subclass: 2.2.2 Type: HA beta-beta hairpin DB: ArchDB-EC Image coordinates: Consensus coordinates: |
Number of loops: 127 Average sequence ID (%) : 17.1 +/- 16.2 Average RMSD (Å) : 0.291 +/- 0.095 Consensus geometry
|
Consensus Sequence: | XXXpGX |
(φψ)-conformation: | bbaaeb |
Pattern: | x | x | x | [acdgnstv] | x | [adegknqrst] | [gk] | x | x | x |
Conservation: | -0.349 | -0.218 | -0.448 | -0.193 | -0.211 | -0.227 | 2.830 | -0.432 | -0.280 | -0.471 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1ako_*_91 | 1ako | - | 95 | 104 | EIPSLLGNVT | EEEETTEEEE | bbxbaaebbx |
1ao0_A_213 | 1ao0 | A | 215 | 224 | LIINDEGMKS | EEEETTEEEE | bbbbaaebbb |
1ayl_*_271 | 1ayl | - | 271 | 280 | HGWDDDGVFN | EEE-SS-EEE | bbbbaaexbx |
1b37_A_237 | 1b37 | A | 240 | 249 | IKYSPGGVTV | EEE-SS-EEE | bbbbaaebbb |
1b8a_A_34 | 1b8a | A | 38 | 47 | WIRDRDGIVQ | EEEETTEEEE | bbbbaaebbx |
1bbz_A_36 | 1bbz | A | 38 | 47 | EAQTKNGQGW | EEEETTEEEE | xbbbaaebex |
1c4t_A_272 | 1c4t | A | 272 | 279 | .VSTPRGLV. | .EEETTEEE. | .bxbaaexb. |
1dgf_A_131 | 1dgf | A | 135 | 144 | KFYTEDGNWD | EEEETTEEEE | bbxxaaexbb |
1dp4_A_355 | 1dp4 | A | 356 | 365 | SFQGVTGYLK | EEEETTEEEE | bbbbaaexbb |
1dx4_A_6 | 1dx4 | A | 6 | 15 | VVQTSSGPVR | EEEETTEEEE | bbxxaaewbb |
1e1o_A_82 | 1e1o | A | 86 | 95 | TLQDVGGRIQ | EEEETTEEEE | bbbbaaebbx |
1e2t_A_142 | 1e2t | A | 142 | 150 | .QQTPHGEYR | .EEETTEEEE | .xbbaaebbb |
1ea5_A_7 | 1ea5 | A | 7 | 16 | LVNTKSGKVM | EEEETTEEEE | bbxbaaexbb |
1ec7_A_26 | 1ec7 | A | 26 | 31 | ..MNLSGA.. | ..EETTEE.. | ..xbaaeb.. |
1ee0_A_263 | 1ee0 | A | 263 | 268 | ..LREGGL.. | ..EETTEE.. | ..xbaaex.. |
1em6_A_205 | 1em6 | A | 206 | 215 | VEHTNTGTKW | EEEETTEEEE | xbxxaaexbx |
1em9_A_2 | 1em9 | A | 2 | 11 | VVIKTEGPAW | EEE-SSSEEE | bbxbaaewbx |
1evu_A_155 | 1evu | A | 162 | 171 | AVWTPYGVLR | EEEETTEEEE | bbxbaaebbb |
1f0n_A_86 | 1f0n | A | 86 | 93 | .ACGKAGCQ. | .EEETTEEE. | .xxbaaebb. |
1f1j_A_149 | 1f1j | A | 149 | 158 | VIYGKDGVTP | EEE-SSSEEE | bbxxaaebbx |
1f89_A_155 | 1f89 | A | 156 | 165 | TIDTKYGKFG | EEEETTEEEE | bxxbaaebbx |
1fui_A_323 | 1fui | A | 323 | 328 | ..FDWNGV.. | ..EETTEE.. | ..bbaaex.. |
1fur_A_5 | 1fur | A | 6 | 15 | SEKDSMGAID | EEEETTEEEE | bbbbaaexbx |
1gg4_A_260 | 1gg4 | A | 263 | 272 | TLQTPTGSVD | EEEETTEEEE | xxbbaaebbx |
1gkr_A_2 | 1gkr | A | 10 | 19 | RLVSSDGITE | EEEETTEEEE | bxbbaaebbx |
1gof_*_372 | 1gof | - | 372 | 377 | ..QSNRGV.. | ..EETTEE.. | ..bbaaex.. |
1gpu_A_189 | 1gpu | A | 189 | 194 | ..ITIDGA.. | ..EETTEE.. | ..bbaaex.. |
1gqz_A_237 | 1gqz | A | 239 | 248 | QVDLPGGSLM | EEEETTEEEE | xbbxaaebbb |
1gqz_A_94 | 1gqz | A | 96 | 105 | SVSTQKGNMV | EEE-SS-EEE | xbxbaaexbb |
1gwe_A_116 | 1gwe | A | 120 | 129 | RFYTEEGNYD | EEEETTEEEE | bbxxaaexbb |
1gz8_A_4 | 1gz8 | A | 10 | 19 | IGEGTYGVVY | EEE-SSSEEE | aebxaaexbb |
1he7_A_357 | 1he7 | A | 362 | 371 | LAANPFGQAS | EEEETTEEEE | bbbbaaebbb |
1hwx_A_269 | 1hwx | A | 272 | 280 | AVGESDGSI. | EEEETTEEE. | bbbbaaebb. |
1hzy_A_36 | 1hzy | A | 36 | 45 | RINTVRGPIT | EEEETTEEEE | bbxbaaexbx |
1j2p_A_37 | 1j2p | A | 39 | 48 | GIKCKEGVIL | EEEETTEEEE | bbbbaaebbb |
1j2q_H_3 | 1j2q | H | 5 | 14 | GLVCKDGVVM | EEEETTEEEE | bbxxaaebbb |
1j2q_H_97 | 1j2q | H | 102 | 111 | GGIDSEGKSI | EEEETTEEEE | bebbaaebbb |
1j9b_A_96 | 1j9b | A | 96 | 105 | IVVTPLGTRL | EEEETTEEEE | xbbbaaebbx |
1jbw_A_238 | 1jbw | A | 241 | 250 | TYEDQDGRIS | EEEETTEEEE | bbbbaaebbx |
1jcl_A_37 | 1jcl | A | 37 | 42 | ..KTPVGN.. | ..EETTEE.. | ..xbaaex.. |
1jg1_A_196 | 1jg1 | A | 201 | 210 | VRKTKDGIKI | EEEETTEEEE | bbxxaaexbb |
1ji1_A_99 | 1ji1 | A | 101 | 109 | AWYNGNGPS. | EEEETTEEE. | bbbbaaewb. |
1ji2_A_93 | 1ji2 | A | 94 | 102 | VYFGETGFS. | EEEETTEEE. | bxbbaaebb. |
1jv1_A_490 | 1jv1 | A | 490 | 499 | LIIDENGVHE | EEEETTEEEE | bbbbaaexbb |
1jxh_A_188 | 1jxh | A | 188 | 197 | WLFTREGEQR | EEE-SS-EEE | bbbbaaebbx |
1k0e_A_241 | 1k0e | A | 244 | 253 | FLRLEQGAIL | EEE-SS-EEE | bbbbaaebbb |
1k2y_X_409 | 1k2y | X | 410 | 419 | RVDYPKGWGL | EEEETTEEEE | bbbxaaebbb |
1k38_A_212 | 1k38 | A | 218 | 227 | WVEWPTGSVF | EEEETTEEEE | bbxbaaebbx |
1k4g_A_113 | 1k4g | A | 115 | 124 | TKQSEEGVTF | EEE-SS-EEE | xbxbaaebbb |
1k4g_A_25 | 1k4g | A | 29 | 38 | TIEMKRGVIR | EEEETTEEEE | bbxbaaebbx |
1k82_A_57 | 1k82 | A | 59 | 68 | LLELPEGWII | EEE-SS-EEE | bbxbaaebxb |
1ka8_A_76 | 1ka8 | A | 76 | 85 | KRHTKQGIQT | EEEETTEEEE | bbxbaaexbb |
1khb_A_550 | 1khb | A | 550 | 559 | TKLTPIGYIP | EEEETTEEEE | bbxbaaexbx |
1kht_A_94 | 1kht | A | 94 | 103 | TVSTPKGYLP | EEEETTEEEE | bbxbaaexbx |
1kjq_A_202 | 1kjq | A | 208 | 217 | TVSAVDGVHF | EEEETTEEEE | bbbbaaebbb |
1kt8_A_37 | 1kt8 | A | 41 | 48 | VEWNDKGW.. | EEEETTEE.. | bbbbaaex.. |
1kuu_A_6 | 1kuu | A | 9 | 18 | VGRNSNGSFV | EEE-SS-EEE | bebbaaebbb |
1l0w_A_35 | 1l0w | A | 38 | 47 | DLRDREGLVQ | EEEETTEEEE | xxbbaaebbx |
1l3s_A_334 | 1l3s | A | 336 | 345 | AVVNEHGRFF | EEEETTEEEE | bbbbaaebbb |
1l5r_A_205 | 1l5r | A | 206 | 215 | VEHTNTGTKW | EEE-SS-EEE | xbxbaaexbb |
1l8a_A_262 | 1l8a | A | 262 | 267 | ..QRLDGP.. | ..EETTEE.. | ..bbaaex.. |
1lbv_A_125 | 1lbv | A | 126 | 135 | YYADSSGAYR | EEEETTEEEE | bbbbaaebbb |
1lgt_A_30 | 1lgt | A | 32 | 41 | AGTTDNGDLF | EEEETTEEEE | aebbaaexbb |
1lk5_A_215 | 1lk5 | A | 217 | 226 | IVGTREGVKK | EEEETTEEEE | bbxbaaexbb |
1llf_A_502 | 1llf | A | 503 | 512 | MMINALGLYT | EEEETTEEEE | xbbbaaebbb |
1lop_A_2 | 1lop | A | 3 | 12 | TFHTNHGDIV | EEEETTEEEE | bxxbaaexbb |
1lpp_*_502 | 1lpp | - | 503 | 512 | MMINALGLYT | EEE-SS-EEE | xbbbaaebbb |
1lqp_A_29 | 1lqp | A | 31 | 40 | EARWDQGAYL | EEEETTEEEE | abbbaaebbb |
1ltz_A_187 | 1ltz | A | 187 | 196 | LINTPAGMRI | EEEETTEEEE | bbxbaaexbb |
1lvm_A_54 | 1lvm | A | 56 | 65 | LVQSLHGVFK | EEEETTEEEE | xbxbaaebbb |
1m0s_A_206 | 1m0s | A | 208 | 217 | IVGTPEGAKV | EEEETTEEEE | bbxbaaexbx |
1m3k_A_202 | 1m3k | A | 203 | 212 | IVKGRKGDIT | EE--TT--EE | xxxbaaexbx |
1m4i_A_138 | 1m4i | A | 139 | 148 | SVLAPTGPVR | EEEETTEEEE | bbxxaaewbx |
1m5y_A_255 | 1m5y | A | 258 | 267 | PIRSGVGFHI | EEEETTEEEE | pxxbaaebbb |
1m7s_A_133 | 1m7s | A | 137 | 146 | KFYTADGNWD | EEEETTEEEE | xxxxaaexbb |
1mbm_A_91 | 1mbm | A | 94 | 103 | SWCTATGDEE | EEEETTEEEE | bxxxaaexbx |
1mo9_A_289 | 1mo9 | A | 293 | 302 | VAMTPNGEMR | EEEETTEEEE | bbxbaaexbb |
1mpp_*_238 | 1mpp | - | 238 | 246 | .TESQQGYTV | .EEETTEEEE | .xxbaaebbb |
1n5m_A_9 | 1n5m | A | 9 | 18 | LVRVRGGQLR | EEEETTEEEE | bbbbaaexbb |
1n62_B_169 | 1n62 | B | 169 | 174 | ..TGAHGA.. | ..EETTEE.. | ..bxaaex.. |
1n62_C_135 | 1n62 | C | 137 | 146 | ELTGPEGARI | EEEETTEEEE | xbbbaaexbb |
1nme_A_126 | 1nme | A | 126 | 135 | IIFGTNGPVD | EEEETTEEEE | bbxxaaexbx |
1nnj_A_92 | 1nnj | A | 95 | 104 | TMKFADGQLI | EEE-SS-EEE | bbxbaaebbb |
1ntg_A_150 | 1ntg | A | 151 | 158 | NFMTKLGS.. | EEEETTEE.. | xxbbaaex.. |
1nuw_A_1171 | 1nuw | A | 1174 | 1183 | VLAMVNGVNC | EEEETTEEEE | bbbbaaebbb |
1o0s_A_357 | 1o0s | A | 358 | 365 | YLMDIDGL.. | EEEETTEE.. | bbbbaaex.. |
1o17_A_230 | 1o17 | A | 234 | 243 | KIVSKRGIEE | EEEETTEEEE | bbbbaaebbx |
1o8b_A_205 | 1o8b | A | 207 | 216 | LIGTPDGVKT | EEEETTEEEE | bbxbaaexxb |
1oal_A_15 | 1oal | A | 21 | 30 | LSQNKYGVVF | EEEETTEEEE | bbxbaaexbb |
1odm_A_231 | 1odm | A | 232 | 241 | QVETAAGYQD | EEEETTEEEE | bbxbaaexbx |
1olt_A_307 | 1olt | A | 307 | 314 | .HRNFQGYT. | .EE-SS-EE. | .bbbaaexb. |
1one_A_17 | 1one | A | 22 | 31 | ELTTEKGVFR | EEEETTEEEE | bbbbaaebbb |
1p1j_A_94 | 1p1j | A | 94 | 101 | .FQTKEGVK. | .EEETTEEE. | .bxbaaexb. |
1pin_A_150 | 1pin | A | 150 | 158 | .VFTDSGIHI | .EE-SS-EEE | .bxbaaebbb |
1prx_A_15 | 1prx | A | 15 | 24 | EANTTVGRIR | EEEETTEEEE | bbxbaaexbb |
1ps9_A_595 | 1ps9 | A | 597 | 606 | QKIDDDGLHV | EEEETTEEEE | abbbaaebxb |
1q8y_A_230 | 1q8y | A | 233 | 242 | NHKGPNGVHV | EEEETTEEEE | xbxbaaexbx |
1qe3_A_5 | 1qe3 | A | 5 | 14 | IVTTQYGKVK | EEEETTEEEE | xbxxaaexbb |
1qht_A_535 | 1qht | A | 537 | 546 | LYADTDGLHA | EEEETTEEEE | abbbaaebbb |
1qi7_A_50 | 1qi7 | A | 54 | 63 | NFQSSRGTVS | EEEETTEEEE | bbbbaaebbb |
1qjv_A_272 | 1qjv | A | 272 | 281 | TTTFSDGRYA | EEEETTEEEE | pbxbaaebbp |
1qnt_A_19 | 1qnt | A | 21 | 30 | LSGCEQGLHE | EEEETTEEEE | bbbbaaexab |
1qrp_E_292 | 1qrp | E | 292 | 297 | ..PTESGE.. | ..EETTEE.. | ..xbaaex.. |
1rlr_*_642 | 1rlr | - | 644 | 653 | IKASKDGILR | EEEETTEEEE | xbxbaaexxb |
1ryp_2_3 | 1ryp | 2 | 5 | 14 | SMKYDNGVII | EEEETTEEEE | bbbbaaebbb |
1ryp_B_34 | 1ryp | B | 36 | 45 | GIKATNGVVI | EEEETTEEEE | bbbbaaebbb |
1ryp_C_35 | 1ryp | C | 37 | 46 | GIMASDGIVL | EEEETTEEEE | bbxbaaebbb |
1ryp_E_37 | 1ryp | E | 39 | 48 | GIATKEGVVL | EEE-SS-EEE | bbbbaaebbb |
1ryp_F_130 | 1ryp | F | 135 | 144 | IGYDKSGAHL | EEEETTEEEE | bbbbaaexbb |
1ryp_I_96 | 1ryp | I | 101 | 110 | AGVDPTGSHL | EEEETTEEEE | bebbaaebbb |
1ryp_K_178 | 1ryp | K | 181 | 190 | KIVDKDGIRQ | EEEETTEEEE | bbbbaaebbx |
1ryp_L_3 | 1ryp | L | 5 | 14 | AFRFQGGIIV | EEEETTEEEE | bbxbaaebbb |
1sfe_*_15 | 1sfe | - | 18 | 27 | LADCELGRCL | EEEETTEEEE | bbxbaaexbb |
1sfe_*_24 | 1sfe | - | 28 | 37 | VAESERGICA | EEE-SSSEEE | bbbxaaepab |
1svp_A_187 | 1svp | A | 188 | 197 | FYNWHHGAVQ | EEEETTEEEE | bbbbaaexbb |
1tca_*_309 | 1tca | - | 309 | 314 | ..RTCSGI.. | ..EETTEE.. | ..bbaaex.. |
1tgo_A_157 | 1tgo | A | 161 | 170 | SYADEEGARV | EEEETTEEEE | bbbbaaebbb |
1tmo_*_10 | 1tmo | - | 11 | 20 | TTGSHFGAFK | EEEETTEEEE | bbbbaaexbb |
1trb_*_206 | 1trb | - | 210 | 219 | VTGDQMGVTG | EEE-SSSEEE | bbbbaaexab |
1ubk_L_469 | 1ubk | L | 474 | 483 | FVNAPRGGLS | EEEETTEEEE | bbxxaaexbb |
1uxy_*_327 | 1uxy | - | 327 | 334 | RFIGASGE.. | EEEETTEE.. | xxbxaaex.. |
1vsr_A_145 | 1vsr | A | 145 | 154 | AQIDTQGIHL | EEEETTEEEE | bbbbaaebbx |
1wwc_A_374 | 1wwc | A | 379 | 388 | IAKNPLGTAN | EEEETTEEEE | bbbbaaebbb |
2bc2_A_39 | 2bc2 | A | 45 | 54 | VLNTSKGLVL | EEEETTEEEE | bbxbaaexbb |
2bce_*_6 | 2bce | - | 6 | 14 | .VYTEGGFVE | .EEETTEEEE | .bxbaaexbb |
2hrv_A_109 | 2hrv | A | 109 | 118 | KLLCKHGVIG | EEEETTEEEE | xbbbaaexab |
2not_A_75 | 2not | A | 75 | 84 | YYCGENGPYC | EEEETTEEEE | bbxxaaewbx |
2pva_A_153 | 2pva | A | 156 | 165 | IEPDKTGITI | EEEETTEEEE | bbwxaaexbb |
5mdh_A_198 | 5mdh | A | 198 | 207 | KVKLQAKEVG | EEE-SS-EEE | bbxxaaexbx |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1gpu_A_189 | 1gpu | A | AC1CA BINDING SITE FOR CHAIN A | I - 189 |
1gz8_A_4 | 1gz8 | A | MBPMBP BINDING SITE FOR CHAIN A | I - 10 |
1gz8_A_4 | 1gz8 | A | MBPMBP BINDING SITE FOR CHAIN A | G - 11 |
1gz8_A_4 | 1gz8 | A | MBPMBP BINDING SITE FOR CHAIN A | E - 12 |
1olt_A_307 | 1olt | A | AC3SAM BINDING SITE FOR CHAIN A | F - 310 |
1pin_A_150 | 1pin | A | ACTTHE ACTIVE SITE OF THE PPIASE DOMAIN IS MARKED BY THE BOUND ALA-PRO DIPEPTIDE (CHAIN B). | H - 157 |
Clusters included in this Subclass |
CLUSTER: HA.1.2 |
CLUSTER: HA.2.2 |
CLUSTER: HA.3.4 |
CLUSTER: HA.3.67 |
CLUSTER: HA.4.23 |
CLUSTER: HA.4.77 |
CLUSTER: HA.5.17 |
CLUSTER: HA.5.70 |